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The map label for this gene is nanA [H]

Identifier: 225859446

GI number: 225859446

Start: 1604204

End: 1607047

Strand: Reverse

Name: nanA [H]

Synonym: SP70585_1731

Alternate gene names: 225859446

Gene position: 1607047-1604204 (Counterclockwise)

Preceding gene: 225859447

Following gene: 225859445

Centisome position: 73.56

GC content: 41.91

Gene sequence:

>2844_bases
ATGATTGTAGGAGCAGTGGTATTTGGAACGTCTCCTGTTTTAGCTCAAGAAGGGGCAAGTGAGCAACCTCTGGCAAATGA
AACTCAACTTTCGGGGGAGAGCTCAACCCTAACTGATACAGAAAAGAGCCAGCCTTCTTCAGAGACTGAACTTTCTGGCA
ATAAGCAAGAACAAGAAAGGAAAGATAAGCAAGAAGAAAAAATTCCAAGAGATTACTATGCACGAGATTTGGAAAATGTC
GAAACAGTGATAGAAAAAGAAGATGTTGAAACCAATGCTTCAAATGGTCAGAGAGTTGATTTATCAAGTGAACTAGATAA
ACTAAAGAAACTTGAAAACGCAACAGTTCACATGGAGTTTAAGCCAGATGCATCAGCTCCACGCTTTTACAATCTCTTCT
CTGTATCCAGTGACACCAAGGAAAATGAGTACTTTACTATGTCGGTCCTTGATAATACAGCTCTTATTGAAGGGCGTGGC
GCTAACGGAGAGCAGTTCTATGATAAGTATACAGATGCTCCTTTGAAAGTTCGCCCAGGACAATGGAATTCCGTGACCTT
TACTGTCGAACAACCGACAGCGGAGTTACCTCATGGACGAGTTCGTCTCTATGTGAACGGTGTCTTATCTCGAACAAGTC
TCAAATCTGGTAACTTTATCAAAGATATGCCAGATGTTAATCAAGCTCAACTTGGAGCAACCAAACGGGGCAATAAGACA
GTTTGGGGAAGCAATCTACAAGTTCGAAACCTAACCGTCTATGATCGTGCCTTAAGCCCAGAAGAAGTTCAGACGAGAAG
CCAACTATTTGAAAGAGGTGATTTGGAGAAGAAACTTCCAGAAGGTGCGAAAATCTCAGAGAAAGAAGACGTCTTTGAAG
GGGGAATGAACAACAAACCAAATAAAGATGGAATTAAGAGTTATCGTATTCCAGCTCTTCTCAAGACAGATAAAGGAACT
CTGATTGCAGGTGCAGATGAACGCCGTCTTCATTCTAGTGACTGGGGTGATATCGGTATGGTCATCAGACGTAGTGAAGA
TAATGGTAAAACTTGGGGTGACCGAGTAACCATTACCAACTTACGTGACAATCCAAAAGCTTCTGACCCATCGATCGGTT
CACCAGTGAATATCGATATGGTGTTGGTTCAAGATCCTGAAACCAAACGAATCTTTTCTATCTATGACATGTTCCCAGAA
GGGAAGGGAATCTTTGGAATGTCTTCACAAAAAGAAGAAGCCTACAAAAAAATCGATGGAAAAACCTATCAAATCCTCTA
TCGTGAAGGAGAAAAGGGAGCTTATACCATTCGAGAAAATGGTACTGTCTATACACCAGATGGTAAGGCGACAGACTATC
GCGTTGTTGTAGATCCTGTTAAACCAGCCTATAGCGACAAGGGTGATCTATACAAGGGTGACCAATTACTAGGCAATATC
TACTTCACAACAAACAAAACTTCTCCATTTAGAATTGCCAAGGATAGCTATCTATGGATGTCCTACAGTGATGACGACGG
GAAGACATGGTCAGCGCCTCAAGATATTACTCCGATGGTCAAAGCCGATTGGATGAAATTCTTGGGTGTAGGTCCTGGAA
CAGGAATTGTACTTCGGAATGGGCCTCACAAGGGACGGATTTTGATACCGGTTTATACGACTAATAATGTATCTCACTTA
AATGGCTCGCAATCTTCTCGTGTCATCTATTCAGATGATCATGGAAAAACTTGGCATGCTGGAGAAGCGGTCAACGATAA
CCGTCAGGTAGACGGTCAAAAGATCCACTCTTCTACGATGAACAATAGACGTGCGCAAAATACAGAATCAACGGTGGTAC
AACTAAACAATGGAGATGTTAAACTCTTTATGCGTGGTTTGACTGGAGATCTTCAGGTTGCTACAAGTAAAGACGGAGGA
GTGACTTGGGAGAAGGATATCAAACGTTATCCACAGGTTAAAGATGTCTATGTTCAAATGTCTGCTATCCATACGATGCA
TAATGGAAAAGAATACATCATCCTCAGCAATGCAGGTGGACCGAAACGTGAAAATGGGATGGTCCACTTGGCTCGTGTCG
AAGAAAATGGTGAGTTGACTTGGCTCAAACACAATCCAATTCAAAAAGGAGAGTTTGCCTATAATTCGCTCCAAGAATTA
GGAAATGGGGAGTATGGCATCTTGTATGAACATACTGAAAAAGGACAAAATGCCTATACCCTATCATTTAGAAAATTTAA
TTGGGAATTTTTGAGCAAAAATCTGATTTCTCCTACCGAAGCGAAAGTGAAGCGAACTAGAGAGATGGGCAAAGGAGAGA
TGGGCAAAGGAGTTATTGGCTTGGAGTTCGACTCAGAAGTATTGGTCAACAAGGCTCCAACCCTTCAATTGGCAAATGGT
AAAACAGCGACTTTCCTAACCCAGTATGATAGCAAGACCTTGTTGTTTGCAGTAGATAAGGAAGATATCGGACAGGAAAT
TATTGGTATAGCTAAAGGAAGCATCGAAAGTATGCATAATCTTCCTGTAAATCTAGCAGGTGCCAGAGTTCCTGGCGGAG
TAAATGGTAGCAAAGCAGCGGTGCATGAAGTTCCAGAATTTACAGGGGGAGTTAATGGTACAGAGCCAGCTGTTCATGAA
ATCGCAGAGTATAAGGGATCTGATTCGCTTGTAACTCTTACTACAAAAGAAGATTATACTTACAAAGCTCCTCTTGCTCA
GCAGGCACTTCCTGAAACAGGAAACAAGGAGAGTGACCTCCTAGCTTCACTAGGACTAACAGCTTTCTTCCTTGGTCTGT
TTACGCTAGGGAAAAAAGAGAGAACAATAAGAGAAGAATTCTAA

Upstream 100 bases:

>100_bases
AAATCGGGATATAGATATAGAGAGGATCAGTATGAATCGGAGTGTTCAAGAACGTAAGTGTCGTTATAGCATTAGGAAAC
TATCGGTAGGAGCGGTTTCT

Downstream 100 bases:

>100_bases
ACATTTGATTTTGTAAAAATAGAAGGAGATAGCAGGTTTTCAAGCCTGCTATCTTTTTTTGATGACATTCAGGCTGATAC
GAAATCATAAGAGGTCTGAA

Product: neuraminidase

Products: NA

Alternate protein names: Neuraminidase A [H]

Number of amino acids: Translated: 947; Mature: 947

Protein sequence:

>947_residues
MIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLENV
ETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSSDTKENEYFTMSVLDNTALIEGRG
ANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAELPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKT
VWGSNLQVRNLTVYDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIPALLKTDKGT
LIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPE
GKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNI
YFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHL
NGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGG
VTWEKDIKRYPQVKDVYVQMSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQEL
GNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMGKGVIGLEFDSEVLVNKAPTLQLANG
KTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHE
IAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF

Sequences:

>Translated_947_residues
MIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLENV
ETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSSDTKENEYFTMSVLDNTALIEGRG
ANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAELPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKT
VWGSNLQVRNLTVYDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIPALLKTDKGT
LIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPE
GKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNI
YFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHL
NGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGG
VTWEKDIKRYPQVKDVYVQMSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQEL
GNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMGKGVIGLEFDSEVLVNKAPTLQLANG
KTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHE
IAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF
>Mature_947_residues
MIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLENV
ETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSSDTKENEYFTMSVLDNTALIEGRG
ANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAELPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKT
VWGSNLQVRNLTVYDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIPALLKTDKGT
LIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPE
GKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNI
YFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHL
NGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGG
VTWEKDIKRYPQVKDVYVQMSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQEL
GNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMGKGVIGLEFDSEVLVNKAPTLQLANG
KTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHE
IAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF

Specific function: Unknown

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 BNR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR004124
- InterPro:   IPR005877
- InterPro:   IPR001791
- InterPro:   IPR019931
- InterPro:   IPR011040
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02012 BNR; PF02973 Sialidase; PF04650 YSIRK_signal [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 105155; Mature: 105155

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQER
CEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
KDKQEEKIPRDYYARDLENVETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEF
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEEE
KPDASAPRFYNLFSVSSDTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPG
CCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHCCCCEEECCC
QWNSVTFTVEQPTAELPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKT
CCCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEE
VWGSNLQVRNLTVYDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKP
EECCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCC
NKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITN
CCCCCHHCCCCEEEECCCCCEEECCCHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEE
LRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDG
CCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCEECCCCCHHHHHHHHCC
KTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNI
CEEEEEEEECCCCEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCCCCEECCEEEEEE
YFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRN
EEEECCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
GPHKGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTM
CCCCCEEEEEEEECCCEEECCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHH
NNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQM
CCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCEEEHHHHHHCCCHHHHHEEH
SAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQEL
HHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHH
GNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMGKGVIG
CCCCEEEEEEECCCCCCEEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEE
LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHN
EEECCCEEECCCCEEEECCCCEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCHHHHHC
LPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTKEDYT
CCEEEECCCCCCCCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCE
YKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF
EECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MIVGAVVFGTSPVLAQEGASEQPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQER
CEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
KDKQEEKIPRDYYARDLENVETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEF
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEEE
KPDASAPRFYNLFSVSSDTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPG
CCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHCCCCEEECCC
QWNSVTFTVEQPTAELPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKT
CCCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEE
VWGSNLQVRNLTVYDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKP
EECCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCC
NKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITN
CCCCCHHCCCCEEEECCCCCEEECCCHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEE
LRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDG
CCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCEECCCCCHHHHHHHHCC
KTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNI
CEEEEEEEECCCCEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCCCCEECCEEEEEE
YFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRN
EEEECCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
GPHKGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTM
CCCCCEEEEEEEECCCEEECCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHH
NNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQM
CCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCEEEHHHHHHCCCHHHHHEEH
SAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQEL
HHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHH
GNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMGKGVIG
CCCCEEEEEEECCCCCCEEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEE
LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHN
EEECCCEEECCCCEEEECCCCEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCHHHHHC
LPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTKEDYT
CCEEEECCCCCCCCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCE
YKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF
EECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8063384; 8759848 [H]