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The map label for this gene is murB

Identifier: 225859156

GI number: 225859156

Start: 1326936

End: 1327841

Strand: Reverse

Name: murB

Synonym: SP70585_1428

Alternate gene names: 225859156

Gene position: 1327841-1326936 (Counterclockwise)

Preceding gene: 225859157

Following gene: 225859155

Centisome position: 60.78

GC content: 45.03

Gene sequence:

>906_bases
ATGTCTGTAAGAGAAAAAATGCTTGAAATCTTAGAAGGAATTGATATCCGTTTTCAGGAACCCTTGCATAGCTATAGTTA
TACAAAAGTAGGTGGAGAGGCTGATTATTTGGTCTTTCCACGAAATCGTTTTGAGTTGGCTCGCGTTGTGAAATTTGCCA
ACCAAGAAAATATCCCTTGGATGGTTCTTGGCAATGCAAGCAATATCATCGTTCGTGATGGTGGGATTCGTGGATTTGTC
ATCTTGTGTGACAAGCTCAATAACGTTTCTGTTGATGGCTATACCATTGAAGCAGAAGCTGGGGCTAACTTGATTGAAAC
AACTCGCATTGCCCTCCGTCATAGTTTGACTGGCTTTGAGTTTGCTTGTGGTATTCCAGGAAGCGTTGGCGGTGCTGTCT
TTATGAATGCGGGTGCCTATGGTGGCGAGATTGCTCACATATTGCAGTCTTGTAAGGTCTTGACCAAGGATGGAGAAATC
GAAACCCTGTCTGCTAAAGACTTGGCTTTTGGTTACCGCCATTCAGCTATTCAGGAGTCTGGTGCAGTTGTCTTGTCAGT
TAAATTTGCCCTAGCCCCAGGAACCCATCAGGTTATCAAGCAGGAAATGGACCGCTTGACGCACCTACGTGAACTCAAGC
AACCTTTGGAATACCCATCTTGTGGCTCGGTCTTTAAGCGTCCAGTCGGGCATTTTGCAGGTCAGTTAATTTCAGAAGCT
GGCTTGAAAGGCTATCGTATCGGTGGCGTAGAAGTGTCAGAAAAGCATGCAGGATTTATGATCAATGTCGCAGATGGAAC
GGCCAAAGACTACGAGGACTTGATCCAATCGGTTATCGAAAAAGTCAAGGAACACTCAGGTATTACGCTTGAAAGAGAAG
TCCGGATCTTGGGTGAAAGCAAGTAG

Upstream 100 bases:

>100_bases
CCTCTTTTTCTTATGCAAAATCCAAACAAGGTATTTTTATGGTCGTCAAATGTCTCTAAAAATGGTATAATGGAATGAAT
TTTGTAAAAGGAAGAGTGAC

Downstream 100 bases:

>100_bases
GAAGCTGTATTTGAAAAGCTGCTGCTATGTCATGGAAAGGGGGGTGAAAGCCTATCGGTAGCGAAGATGTATGCAGGTGG
TTTTACTCCCTGCAAGAGGT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFV
ILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEA
GLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESK

Sequences:

>Translated_301_residues
MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFV
ILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEA
GLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESK
>Mature_300_residues
SVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVI
LCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEIE
TLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEAG
LKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=332, Percent_Identity=25.9036144578313, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32956; Mature: 32825

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPW
CCHHHHHHHHHCCCCCEECCCHHCCCCEECCCCCCEEEECCCHHHHHHHHHHCCCCCCCE
MVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFE
EEECCCCEEEEECCCCEEEEEEEECCCCEEECCEEEECCCCCCHHHHHHHHHHHCCCCCE
FACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEIETLSAKDLAFGYRHSAIQES
EECCCCCCCCCEEEEECCCCCHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHHHHCC
GAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEA
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGES
CCCCEEECCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
K
C
>Mature Secondary Structure 
SVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPW
CHHHHHHHHHCCCCCEECCCHHCCCCEECCCCCCEEEECCCHHHHHHHHHHCCCCCCCE
MVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFE
EEECCCCEEEEECCCCEEEEEEEECCCCEEECCEEEECCCCCCHHHHHHHHHHHCCCCCE
FACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEIETLSAKDLAFGYRHSAIQES
EECCCCCCCCCEEEEECCCCCHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHHHHCC
GAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEA
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGES
CCCCEEECCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA