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The map label for this gene is aroE

Identifier: 225859143

GI number: 225859143

Start: 1311641

End: 1312495

Strand: Reverse

Name: aroE

Synonym: SP70585_1415

Alternate gene names: 225859143

Gene position: 1312495-1311641 (Counterclockwise)

Preceding gene: 225859144

Following gene: 225859142

Centisome position: 60.08

GC content: 43.27

Gene sequence:

>855_bases
ATGAAGCTTGATGGCTATACACGTTTAGCTGCAGTTGTTGCCAATCCTATTAAGCATTCTATTTCTCCCTTCATCCACAA
TAGAGCCTTTGAGGCGACAGCTACCAACGGTGCTTATGTGGCTTGGGAGATTGAAGCGAGTGACTTGGTAGAAACAGTGG
CCAATATTCGTCGCTACCAGATGTTTGGCATCAATCTGTCCATGCCCTATAAGGAGCAGGTGATTCCTTATTTGGATAAG
CTGAGCGATGAAGCGCGCTTGATTGGTGCGGTTAATACGGTTGTCAATGAGAATGGCAATTTAATTGGATATAATACAGA
TGGCAAGGGATTTTTTAAGTGCTTGCCTTCTTTTACAATTTCAGGTAAAAAGATGATCCTGCTGGGTGCAGGTGGTGCGG
CTAAATCAATCTTGGCACAGGCTATTTTGGATGGCGTCAGTCAGATTTCGGTCTTTGTTCGTTCCGTTTCTATGGAAAAA
ACAAGACCTTACCTAGACAAGTTACAGGAGCAGACAGGCTTTAAAGTGGATTTGTGTGCTTTAGAATATGTTTCTGAACT
GCAAGCAAGGATTGCCGAGTCGGATTTGCTAGTTAATGCCACCAGTGTGGGCATGGATGGCCAATTCTCTCCTGTTCCTG
AAAACATAGTCTTACCAGAAACTCTCTTAGTTGCAGATATCATATACCAACCCTTTGAAACACCGTTTTTGAAATGGGCT
AGAAGTCAGGGCAATCCAGCAGTCAATGGTCTGGGAATGTTGCTCTATCAAGCTGCAGAAGCTTTTCAACTATGGACAGG
CAAGGAAATGCCGACAGAAGAGATTTGGCAGTCTTTAACAGAAAAATACCAATAA

Upstream 100 bases:

>100_bases
GATGTGACTGGTTCGAGTTGGTCTTTTGCCAGTCTGGATGAGGTTAGTGCCCCTGGGCAGATTTCTCTAGCTAGCATGAA
AAAAATCAGGGAGATTTTGG

Downstream 100 bases:

>100_bases
AGAAAGGGAGACTCTCCTATGAAAATCAGAATCGATATTCCTCATCATCCTTATGATATTCAGATTGAAAAAGGTTGTAT
GGCCCAGGCTGGTCAGTGGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVLPETLLVADIIYQPFETPFLKWA
RSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ

Sequences:

>Translated_284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVLPETLLVADIIYQPFETPFLKWA
RSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
>Mature_284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVLPETLLVADIIYQPFETPFLKWA
RSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=277, Percent_Identity=36.4620938628159, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789675, Length=276, Percent_Identity=35.5072463768116, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=284, Percent_Identity=26.7605633802817, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31342; Mature: 31342

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECHHHHHHHHHHHHHHE
MFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTI
EEECEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCEE
SGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHH
LEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVLPETLLVADIIYQPFETPFLKWA
HHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECHHHHHHHHHHHHHHE
MFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTI
EEECEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCEE
SGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHH
LEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVLPETLLVADIIYQPFETPFLKWA
HHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA