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The map label for this gene is aroB

Identifier: 225859142

GI number: 225859142

Start: 1310555

End: 1311622

Strand: Reverse

Name: aroB

Synonym: SP70585_1414

Alternate gene names: 225859142

Gene position: 1311622-1310555 (Counterclockwise)

Preceding gene: 225859143

Following gene: 225859141

Centisome position: 60.04

GC content: 44.76

Gene sequence:

>1068_bases
ATGAAAATCAGAATCGATATTCCTCATCATCCTTATGATATTCAGATTGAAAAAGGTTGTATGGCCCAGGCTGGTCAGTG
GTTGCGAGAACTCTGGCAACCGCAAAAGGTAGTCATTGTGACAGATAACCATGTAGCCTCTCTCTATGCAGAGAAGGTCA
AGCTCAGCCTAGAAGATGCTGGTTTTCAGGTAGCTGTTTTTGATTTCTTAGAAGGTGAAGAAAGAAAGAATTTAACTACT
GTTCAGAAAGTCTATGAATTTCTAGTCAAGCAAGGTCTGACTCGTAGCGATGGAATCGTTGCTCTTGGTGGTGGCGTTGT
TGGGGACCTGGCTGGCTTTGTAGCCTCTACCTATATGCGGGGTATTCACTTTGTTCAGATTCCGACTAGTTTGACAGCTC
AGGTTGATTCTTCTATCGGTGGAAAGACAGGCGTTAACACACCATTTGCTAAAAATATGGTGGGGACCTTTGCCCAACCA
GATGGGGTTCTGATTGATCCACTTGTTCTTGAAACCCTCGGAAAAAGAGAGTTGATTGAAGGGATGGGTGAAGTTATCAA
GTATGGCTTGATTGAGGATCCAGAACTGTGGGCTCTCTTGACGGGACTGAATGGTTCTGTTGAGAGTATTTTGGAACATG
CAGAGACCTTGATTGAACATTCTTGTCAGGTGAAGCGCAAGATGGTGGTTGAAGATGAGTTGGACAATGGTATTCGTCTT
TACCTCAATTTTGGCCACACTATTGGCCATGCCATCGAAGCGACTGCCGGTTATGGCAAGGTCATGCATGGAGAGGCTGT
TGCCATGGGAATGGTACAGATTTCCAAGGTTGCTGAGGAAAAAGGCCTCATGCCAGCTGGCATTACCCAATCTATCACAG
AGATGTGTCAGAAATTCGGCTTGCCTGTTGACTATGAAAATTGGGAAGTTGACAAGCTTTATCAGGCTCTTACTCATGAC
AAGAAAGCGCGTGGTAACACCTTGAAATTGGTCTTGGTGCCAGAGCTTGGTTCAGCGATCATTCACCCAGTTTCTCTGGA
AGAGATGAAAGACTACTTGGTAAAATAA

Upstream 100 bases:

>100_bases
TGCAGAAGCTTTTCAACTATGGACAGGCAAGGAAATGCCGACAGAAGAGATTTGGCAGTCTTTAACAGAAAAATACCAAT
AAAGAAAGGGAGACTCTCCT

Downstream 100 bases:

>100_bases
GGAGAGTGTATGAGATATTTAACTGCAGGAGAATCACACGGCCCCCGTCTAACAGCTATTATTGAGGGAATTCCAGCTGG
ACTTCCATTGACAGCTGAGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK

Sequences:

>Translated_355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK
>Mature_355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=360, Percent_Identity=38.6111111111111, Blast_Score=227, Evalue=9e-61,
Organism=Saccharomyces cerevisiae, GI6320332, Length=345, Percent_Identity=35.0724637681159, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39029; Mature: 39029

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEECCC
GFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMR
CCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIE
CEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECHHHHHHCCHHHHHH
GMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
HHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFG
EEECCCHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
LPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEECCC
GFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMR
CCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIE
CEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECHHHHHHCCHHHHHH
GMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
HHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKVAEEKGLMPAGITQSITEMCQKFG
EEECCCHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
LPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSAIIHPVSLEEMKDYLVK
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA