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The map label for this gene is hpcD [H]

Identifier: 225686905

GI number: 225686905

Start: 1140421

End: 1140813

Strand: Reverse

Name: hpcD [H]

Synonym: BMEA_B1157

Alternate gene names: 225686905

Gene position: 1140813-1140421 (Counterclockwise)

Preceding gene: 225686907

Following gene: 225686904

Centisome position: 96.23

GC content: 58.78

Gene sequence:

>393_bases
ATGCCGCATTTTACAATGGAGTATTCCTCCAATCTCGATGGCACGGTTGATTTCGACGGCCTGTGCCGCGCCGTGCACGA
GACGATTTTGGATACGGGGCTTTTCGAGTTGGGCGCGGTGCGTGTGCGCGCCTTTCGCGCCGAGGCTTATGCCGTTGCCG
ACCTGTTGCCGCAGAATGGTTTCATCGACATGAGCTTTCGCATTGGCGTGGGGCGCAGCGATGAGGAAAAGCGCAAGACC
GGCGAAGCAATCTTTGCCACCGTTACCGAATTTCTGGCCCCGCTGTTCGCCACGCCGCATTTCGCGCTGACGCTGGAGAT
CCGCGAGATCGATCCGCAACTTAGCTGGAAGAAAAACGCCATTCATCCCCGCCTGCGCCAGAAGCAGGCCTGA

Upstream 100 bases:

>100_bases
GATATTATTAACATGTTAAATATAATCGCGACAAATCGCAACAAGGATGAACAGCCTGACGACTGGAGCGGTTTCGGGGC
CGGGTTTCGAGGGAGGAAAA

Downstream 100 bases:

>100_bases
TCCACACGCGCACTACAGCGCGTCGCAGCCGGTTGTTTTCACAGCGCGGCCCACATCACGGAGTAAAGCATGTCCAAGCT
CGACGACAATGTCGCCAAAG

Product: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MPHFTMEYSSNLDGTVDFDGLCRAVHETILDTGLFELGAVRVRAFRAEAYAVADLLPQNGFIDMSFRIGVGRSDEEKRKT
GEAIFATVTEFLAPLFATPHFALTLEIREIDPQLSWKKNAIHPRLRQKQA

Sequences:

>Translated_130_residues
MPHFTMEYSSNLDGTVDFDGLCRAVHETILDTGLFELGAVRVRAFRAEAYAVADLLPQNGFIDMSFRIGVGRSDEEKRKT
GEAIFATVTEFLAPLFATPHFALTLEIREIDPQLSWKKNAIHPRLRQKQA
>Mature_129_residues
PHFTMEYSSNLDGTVDFDGLCRAVHETILDTGLFELGAVRVRAFRAEAYAVADLLPQNGFIDMSFRIGVGRSDEEKRKTG
EAIFATVTEFLAPLFATPHFALTLEIREIDPQLSWKKNAIHPRLRQKQA

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 14654; Mature: 14523

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHFTMEYSSNLDGTVDFDGLCRAVHETILDTGLFELGAVRVRAFRAEAYAVADLLPQNG
CCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
FIDMSFRIGVGRSDEEKRKTGEAIFATVTEFLAPLFATPHFALTLEIREIDPQLSWKKNA
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCC
IHPRLRQKQA
CCCHHHCCCC
>Mature Secondary Structure 
PHFTMEYSSNLDGTVDFDGLCRAVHETILDTGLFELGAVRVRAFRAEAYAVADLLPQNG
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
FIDMSFRIGVGRSDEEKRKTGEAIFATVTEFLAPLFATPHFALTLEIREIDPQLSWKKNA
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCC
IHPRLRQKQA
CCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]