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The map label for this gene is fliC

Identifier: 225686892

GI number: 225686892

Start: 1114318

End: 1115166

Strand: Reverse

Name: fliC

Synonym: BMEA_B1141

Alternate gene names: 225686892

Gene position: 1115166-1114318 (Counterclockwise)

Preceding gene: 225686893

Following gene: 225686891

Centisome position: 94.07

GC content: 54.65

Gene sequence:

>849_bases
ATGGCTAGCATTCTTACAAACTCGTCGGCTCTGACCGCTCTCCAGACGCTTGCTTCGACCAACAAGTCGCTGGAATCGAC
CCAGAACCGTATCTCGACCGGTCTTCGTATTTCTGAAGCTTCGGATAATGCTTCGTACTGGTCCATCGCAACGTCGATGA
AGTCCGACAACAAGGCCAATTCGGCTGTTCAGGACGCTCTCGGCCTCGGCGCCGGCAAGGTCGATACCGCTTATTCCGCG
ATCAACAAGATCCGTGAATCGGTTGACGACATCAAGACCAAGCTTGTTTCGGCTATGGGTGCGAGCACAGAAGACAAGGG
CAAGATCGAAACCGAAATCAAGTCGATCGTCGCTAATATCAACTCGGCTCTCAGCAATGCCAACTACGCGGGTTCCAACC
TGCTGAATGGCCCGACGACCGATCTCAATGTTGTAGCTTCGTACAATCGTTCCGGTAACGCCGTCGCGGTTGACAAGATC
ACTGTCAAGGCTACTGACACTGATGCGAAGACCATGGTTAAAGATATCGTAGATGCGGGTTTCTTCACTTCGGCCTCGGA
CGATACTGCTATTGGTACGGCTCTGAATACGGTTGAAACCGCTCTTGCTTCTCTCGCAACCGGCGCTGCGACGCTCGGTG
CGGCCAAGTCGCAGATCGACAGCCAGAAGAGTTTCCTGTCGGGTCTTCAGGACTCCATCGAAAAGGGCGTCGGTACGCTC
GTCGATGCCGACATGAACAAGGAATCGGCACGTCTGTCGGCTCTCCAGGTTCAGCAGCAGCTTGGCGTTCAGGCTCTGTC
GATCGCCAACTCGTCGAACCAGTCGATCCTGTCGCTGTTCCGCGGCTAA

Upstream 100 bases:

>100_bases
CCCGTGTGTTCGCGGCGACAGGCATGATGCCGCTCCACCATGCCGGTAATCTGAAATCCGGCCTGTCCCTCAGATTGTTT
TTCCCAAGGGGCAAAAAACT

Downstream 100 bases:

>100_bases
TAAACCGGACCGTTTCAGGCAAACAGGGGGGGGGAGTATCCAGCCCGGCCAGATCGGTTTGGATACTTCAGGCGGGGAGG
ACGGGCGCGGAATGAATTCC

Product: Flagellin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKANSAVQDALGLGAGKVDTAYSA
INKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANINSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKI
TVKATDTDAKTMVKDIVDAGFFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTL
VDADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG

Sequences:

>Translated_282_residues
MASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKANSAVQDALGLGAGKVDTAYSA
INKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANINSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKI
TVKATDTDAKTMVKDIVDAGFFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTL
VDADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG
>Mature_281_residues
ASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKANSAVQDALGLGAGKVDTAYSAI
NKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANINSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKIT
VKATDTDAKTMVKDIVDAGFFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTLV
DADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG

Specific function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. The flagellum is required to cause a persistent disease in a murine model of infection

COG id: COG1344

COG function: function code N; Flagellin and related hook-associated proteins

Gene ontology:

Cell location: Secreted. Bacterial flagellum

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial flagellin family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FLIC_BRUME (Q8YDM5)

Other databases:

- EMBL:   AE008918
- PIR:   AD3528
- RefSeq:   NP_541127.1
- ProteinModelPortal:   Q8YDM5
- GeneID:   1197921
- GenomeReviews:   AE008918_GR
- KEGG:   bme:BMEII0150
- NMPDR:   fig|224914.1.peg.2209
- HOGENOM:   HBG758847
- OMA:   TIDVNID
- ProtClustDB:   CLSK898717
- BioCyc:   BMEL224914:BMEII0150-MONOMER
- InterPro:   IPR001492
- InterPro:   IPR001029
- PRINTS:   PR00207

Pfam domain/function: PF00700 Flagellin_C; PF00669 Flagellin_N

EC number: NA

Molecular weight: Translated: 29070; Mature: 28938

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHCCCCHHH
SAVQDALGLGAGKVDTAYSAINKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKITVKATDTDAKTMVKDIVDAG
HHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHC
FFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
VDADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG
ECCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
ASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHCCCCHHH
SAVQDALGLGAGKVDTAYSAINKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKITVKATDTDAKTMVKDIVDAG
HHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHC
FFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
VDADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG
ECCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688