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The map label for this gene is pcaR [H]

Identifier: 225686854

GI number: 225686854

Start: 1072261

End: 1073067

Strand: Reverse

Name: pcaR [H]

Synonym: BMEA_B1094

Alternate gene names: 225686854

Gene position: 1073067-1072261 (Counterclockwise)

Preceding gene: 225686860

Following gene: 225686853

Centisome position: 90.51

GC content: 58.86

Gene sequence:

>807_bases
ATGAAACCGACGACGCAGGACCTGGAAAAAGATTCCGCGCAGGTTTCGAGCGCGCTCGTGCGCGGGTTGGAGATATTGCG
CAGCTTCACACCGCACGATCTGTCGCTGGGCAATCAGGAACTGATTGATCGGACGGGTCTCCCGAAAGCAACGGTTTCAC
GCATGACGGCCACATTGGTCAATCTGGGTTATCTCGACTATGATGAAATGCTGGGGCGTTATCGTATCGGTCCAGCGACG
ATTGCGCTCGGCTATTCCGGGCTGAGCGCCAATGTCGTTGTTCACATAGCGATGCCGCTGATGCGCAAGCTTGCGGAAAA
AACCGGCGTCGCGGTGGCTATGGGCCTTCGGGAACAGCAGGAGATGGTTTACATCGCCAATGCGCGCTCCGAAAATCCTG
TTTCCCTGCGCCTGAATGTCGGTTCGCGGCTCCCCATTTGGAAGACCGCCATGGGGCTTTCATATTATGCCGGTATGGAA
GAGAGCCAGCGTGAGGCGCTGCTGGAGCGCATGCTGCAATGCGAACCGGAACATGCGGAACGAATTTTGCGGCTGACCAA
CCATGCGCTCGATGATTACGCGCGGGATGGCTTCGTTGTCTCCTGCGGCGACTGGTACAGCTATATCAATGCGGTCGGGG
TTCCGTTCCGCCCGACCGACGGGACACAACTCGTCGCCATTACCTGCGGCGGCATTACCGACATTGCCCCGCGCGGTGTC
TGTTACGGCGAGATCGGGCCCGCCCTGAAGGAACTGGCCGCCGAATTGCAGGAGCGGCTCCTAGGCAATTCCAGAGAGGC
GCCTTGA

Upstream 100 bases:

>100_bases
AATGGAATTAAATTTCACTTTTGTCACCTCCCCCCCCCCCCCCTTTTTTCTGCCTTTAGCACTCGCACTGAGAACGTCAG
GAGAAACCGTGAAAAAGAGA

Downstream 100 bases:

>100_bases
GAGCATATTTTCCGTGAAATTCTGAAGGCTGCGAAAGCCCAATTGTTGCAGGACACCCTATGGCCACTGAAATTCTATAT
CCAAAAGTCAGTCTGGAAAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKPTTQDLEKDSAQVSSALVRGLEILRSFTPHDLSLGNQELIDRTGLPKATVSRMTATLVNLGYLDYDEMLGRYRIGPAT
IALGYSGLSANVVVHIAMPLMRKLAEKTGVAVAMGLREQQEMVYIANARSENPVSLRLNVGSRLPIWKTAMGLSYYAGME
ESQREALLERMLQCEPEHAERILRLTNHALDDYARDGFVVSCGDWYSYINAVGVPFRPTDGTQLVAITCGGITDIAPRGV
CYGEIGPALKELAAELQERLLGNSREAP

Sequences:

>Translated_268_residues
MKPTTQDLEKDSAQVSSALVRGLEILRSFTPHDLSLGNQELIDRTGLPKATVSRMTATLVNLGYLDYDEMLGRYRIGPAT
IALGYSGLSANVVVHIAMPLMRKLAEKTGVAVAMGLREQQEMVYIANARSENPVSLRLNVGSRLPIWKTAMGLSYYAGME
ESQREALLERMLQCEPEHAERILRLTNHALDDYARDGFVVSCGDWYSYINAVGVPFRPTDGTQLVAITCGGITDIAPRGV
CYGEIGPALKELAAELQERLLGNSREAP
>Mature_268_residues
MKPTTQDLEKDSAQVSSALVRGLEILRSFTPHDLSLGNQELIDRTGLPKATVSRMTATLVNLGYLDYDEMLGRYRIGPAT
IALGYSGLSANVVVHIAMPLMRKLAEKTGVAVAMGLREQQEMVYIANARSENPVSLRLNVGSRLPIWKTAMGLSYYAGME
ESQREALLERMLQCEPEHAERILRLTNHALDDYARDGFVVSCGDWYSYINAVGVPFRPTDGTQLVAITCGGITDIAPRGV
CYGEIGPALKELAAELQERLLGNSREAP

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=161, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789999, Length=153, Percent_Identity=31.3725490196078, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29387; Mature: 29387

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTTQDLEKDSAQVSSALVRGLEILRSFTPHDLSLGNQELIDRTGLPKATVSRMTATLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
NLGYLDYDEMLGRYRIGPATIALGYSGLSANVVVHIAMPLMRKLAEKTGVAVAMGLREQQ
HCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
EMVYIANARSENPVSLRLNVGSRLPIWKTAMGLSYYAGMEESQREALLERMLQCEPEHAE
CEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
RILRLTNHALDDYARDGFVVSCGDWYSYINAVGVPFRPTDGTQLVAITCGGITDIAPRGV
HHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCC
CYGEIGPALKELAAELQERLLGNSREAP
EEHHCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKPTTQDLEKDSAQVSSALVRGLEILRSFTPHDLSLGNQELIDRTGLPKATVSRMTATLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
NLGYLDYDEMLGRYRIGPATIALGYSGLSANVVVHIAMPLMRKLAEKTGVAVAMGLREQQ
HCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
EMVYIANARSENPVSLRLNVGSRLPIWKTAMGLSYYAGMEESQREALLERMLQCEPEHAE
CEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
RILRLTNHALDDYARDGFVVSCGDWYSYINAVGVPFRPTDGTQLVAITCGGITDIAPRGV
HHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCC
CYGEIGPALKELAAELQERLLGNSREAP
EEHHCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]