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The map label for this gene is argB

Identifier: 225686780

GI number: 225686780

Start: 991685

End: 992575

Strand: Direct

Name: argB

Synonym: BMEA_B1011

Alternate gene names: 225686780

Gene position: 991685-992575 (Clockwise)

Preceding gene: 225686779

Following gene: 225686781

Centisome position: 83.65

GC content: 58.36

Gene sequence:

>891_bases
ATGACGACACTTGAAAACCCCGAAATGCAAGCGCAACTCCTGTCCGCGGCCCTGCCCTATATGCAGCGCTACGAGAACAA
GCACGTCGTTGTGAAATATGGCGGCCACGCCATGGGCAACCCGGAGCTGGGCAAGGCTTTTGCGCGTGATGTCGCGCTTC
TCAAACAGTCGGGCGTCAACCCCATCGTCGTGCATGGAGGGGGGCCGCAGATACAGGCCATGCTGACCAAGCTCGGCATC
GAATCGCGTTTTGAAGGCGGTCTGCGCGTTACCGACGAGAAGACCGTCGAAGTGGTGGAAATGGTTCTGGCCGGCTCCAT
CAACAAGGAAATCGTCGCCCTTATCAATGCGGAAGGCGAATGGGCCATCGGGCTTTGCGGCAAGGATGGCAACATGGTCT
TTGCGCAAAAGGCGCATAAGACCGTCATCGACCCGGATTCCAATATCGAGAAGGTGCTGGATCTAGGCTTTGTCGGAGAA
CCGGCGGAAGTGGACCGTACGCTGCTCGATCTTCTGGCGCGCTCCGAGATGATCCCGGTTATCGCGCCGGTCGCACCGGG
CCGCGACGGCCATACCTACAACATCAATGCCGACACTTTTGCAGGCGCGATTGCCGGTGCTCTGGCTGCAACGCGCCTGT
TGTTCCTGACCAATGTTCCGGGCGTGCTGGACAAGGATAAAAAGCTCATCAAGGAGCTTTCCGTTGCCGATGCACAGGCC
CTTATCAGGGATGGCACCATTTCCGGTGGCATGATTCCGAAGGTGGAAACCTGCATCGATGCAATCCGCCGTGGCGTGGA
AGGCGTTGTCATTCTGAATGGCAAGACCCCGCATTCCGTGCTGCTGGAGCTTTTCACCGAGCATGGTGCCGGCACGCTCA
TCGTGCCGTAA

Upstream 100 bases:

>100_bases
ACATCGCATTATCCTCACGCAAAACCGCTTGGCGTTTTTGCTGGAAATGCTCAAAAAAAGCCCGCCTGTTCTTGCCCTGT
CGCCTGCCATGGAGCCCGCG

Downstream 100 bases:

>100_bases
TAAAAGAAGCACGCTTATCGTGCCTTAATAAAAAAGTACGCTCATCGTGCTGTAGAGCGCGGAAGGATAGACCATGACCG
ATATTCCGGATAGAGCCGCT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGI
ESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGE
PAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQA
LIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP

Sequences:

>Translated_296_residues
MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGI
ESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGE
PAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQA
LIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
>Mature_295_residues
TTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGIE
SRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEP
AEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQAL
IRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=289, Percent_Identity=26.643598615917, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693208, Length=236, Percent_Identity=28.3898305084746, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=277, Percent_Identity=26.3537906137184, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_BRUA1 (B2SC12)

Other databases:

- EMBL:   CP000888
- RefSeq:   YP_001932845.1
- ProteinModelPortal:   B2SC12
- SMR:   B2SC12
- GeneID:   6325896
- GenomeReviews:   CP000888_GR
- KEGG:   bmc:BAbS19_II09140
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31498; Mature: 31367

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVN
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
PIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGE
EEEEECCCHHHHHHHHHHCCHHHCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCC
WAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPV
EEEEEECCCCCEEEEECCCCEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEE
IAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQA
EECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
HHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
TTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVN
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
PIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGE
EEEEECCCHHHHHHHHHHCCHHHCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCC
WAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPV
EEEEEECCCCCEEEEECCCCEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEE
IAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTNVPGVLDKDKKLIKELSVADAQA
EECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
HHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA