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The map label for this gene is alr [H]

Identifier: 225686682

GI number: 225686682

Start: 886917

End: 888107

Strand: Direct

Name: alr [H]

Synonym: BMEA_B0905

Alternate gene names: 225686682

Gene position: 886917-888107 (Clockwise)

Preceding gene: 225686680

Following gene: 225686683

Centisome position: 74.81

GC content: 58.61

Gene sequence:

>1191_bases
ATGTCTTTACCTTTTTCTCAGGATGAGCGCGATCTCGCGGCTGGCGGCATATTGACCATTGATCTCGCAGCCCTGCGCCA
CAATTATTCAGCCATCGCAACCCGCATTGCCCCAACCCGTACGGCCGCTGTGGTAAAGGCAGACGCCTATGGCCTGGGCG
CAAGCCGGGTCGCACCGGCTTTCTACGAGGCCGGTTGCCGCGATTTCTTCGTTGCACATCTTGGCGAAGCAGTGGCGCTG
AAGCCCTTTTTGAAACCCGACGCAACACTTTATGTCCTGAACGGCCTTCAGCCCGGAACGGAAGCAGCCTGTGCCCGCGA
AGGCATCCTGCCTGTTCTCAATTCGCTGGAACAGGTTGAAAACTGGGCAGCACTCGCCACCCGGCTGGGCAAAAAACTGC
CCGCCCTGCTCCAGTTCGATACCGGCATGTCTCGTCTTGGCCTGTCAGCCAAGGAATTTGACCGCCTTCTTGAGAACGTC
ACGCTCCTGAGCAGGATCGACATCAAATTCGCCATCAGCCATCTGGCAAACGGCGACGAGCCGGGAAATGCGGTAAATGC
CCGTCAGCTTGCCAAGATGACGGCCTTGCTCGCTCGCCTGCCGAAACTGCCGGCTGCCTTGGCCAATTCCGGCGGCACCT
TCCTCGGCAAGACCTATTATTTCGATCTCGCCCGCCCCGGCATCGCGCTATATGGCATCGATCCGGAGAGGCAGCATGAC
TTTTCGGATAAGGTGGCGCACGAGAATAAGAAACCCAAGCATTCGATCCTTCCCGTCCTCACCCTTTCGGCGCGTGTCAT
TCAGGTGCGCGACGTCGACAAGGGAGCGACAGTTGGCTATGGCGGCACCTATGTCGCCAACGGCCCGATGCGGATTGCGA
CGATTGCGGTCGGCTATGCTGACGGCTTGTTCCGTTCCTTGAGTAACAAGGGCGCAGCCTTTTTCGGCGATACGCGCCTG
CCCATCATCGGGCGCGTATCGATGGATTCGATCACGCTCGACGTCACCTCATTGCCGGAGGGAACGCTGAAACTCGGCAG
CCTTGTGGAAATGATCGGCCCGCATCAGCGCCTCGAAGACGTGGCGCGGGACTGCGACACTATCCCCTATGAAATTCTGA
CTGCGCTTGGCAACCGTTATGCGCGCGTTTACGTTTACGTGAATGGCGGTGGCACCAGCACAACAGCATAA

Upstream 100 bases:

>100_bases
TGCGCTGTGCTTTTGGGAAAGAGCGCGGGCGCTGATCAAACTTTCGTAAGTATTTACACGAGTTTCGCGAAGCCCGGAAA
GCGTTGGGTGTATGGTTGAG

Downstream 100 bases:

>100_bases
CCACGAGAGGCGTATATGCAGATCACTATTCTCGGTAGCGGCGTCATCGGCGTTACGACGGCCTACTATCTCGCCAAGCT
CGGCCATGAAGTAACGGTCA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVAL
KPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENV
TLLSRIDIKFAISHLANGDEPGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHD
FSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRL
PIIGRVSMDSITLDVTSLPEGTLKLGSLVEMIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA

Sequences:

>Translated_396_residues
MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVAL
KPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENV
TLLSRIDIKFAISHLANGDEPGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHD
FSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRL
PIIGRVSMDSITLDVTSLPEGTLKLGSLVEMIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
>Mature_395_residues
SLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVALK
PFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVT
LLSRIDIKFAISHLANGDEPGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHDF
SDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRLP
IIGRVSMDSITLDVTSLPEGTLKLGSLVEMIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=381, Percent_Identity=30.4461942257218, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=29.2682926829268, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42386; Mature: 42255

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPA
CCCCCCCCCCHHHCCCEEEEEHHHHHCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
FYEAGCRDFFVAHLGEAVALKPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVE
HHHHCHHHHHHHHCCCHHEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHH
NWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVTLLSRIDIKFAISHLANGDE
HHHHHHHHHHHHCCHHHEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHD
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEECCCCEEEEECCCHHCCC
FSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYA
CHHHHHHCCCCCCHHHCHHEECCEEEEEEEECCCCCEECCCCEEEECCCEEEEEEEEHHH
DGLFRSLSNKGAAFFGDTRLPIIGRVSMDSITLDVTSLPEGTLKLGSLVEMIGPHQRLED
HHHHHHHCCCCCEEECCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHH
VARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
HHHHCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPA
CCCCCCCCCHHHCCCEEEEEHHHHHCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
FYEAGCRDFFVAHLGEAVALKPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVE
HHHHCHHHHHHHHCCCHHEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHH
NWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVTLLSRIDIKFAISHLANGDE
HHHHHHHHHHHHCCHHHEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHD
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEECCCCEEEEECCCHHCCC
FSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYA
CHHHHHHCCCCCCHHHCHHEECCEEEEEEEECCCCCEECCCCEEEECCCEEEEEEEEHHH
DGLFRSLSNKGAAFFGDTRLPIIGRVSMDSITLDVTSLPEGTLKLGSLVEMIGPHQRLED
HHHHHHHCCCCCEEECCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHH
VARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
HHHHCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA