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The map label for this gene is lon [H]

Identifier: 225686654

GI number: 225686654

Start: 854867

End: 855571

Strand: Reverse

Name: lon [H]

Synonym: BMEA_B0872

Alternate gene names: 225686654

Gene position: 855571-854867 (Counterclockwise)

Preceding gene: 225686655

Following gene: 225686653

Centisome position: 72.17

GC content: 57.45

Gene sequence:

>705_bases
ATGCAAGTGGGCAATGCCCGGTATAGAACGGCTGCCGATATTCCGGATGTAGTGCCGGTATTCCCTCTCAAGGGGGCGCT
TCTGCTGCCTGGCGGCCAGCTTCCGCTCAATATTTTCGAGCCGCGTTATCTGTCGATGGTGGAAAATGCGCTGGCTGGCA
AGCGAATCATTGGCATGATCCAGCCGAAGATTGATAGCGAAACCGATGATACGGACGAGCCTGTCGATGCGCTGGATGAA
AGCCTGCGCCCGGAACTCAGTCAGGTCGGCTGCCTTGGCCGTATCACGACTTTCGCGGAAATCGGCGATGGCCGCTTGCT
GATTACGCTTCAGGGCATATGCCGTTTCAGGGTTCAGGAAGAGCTTCATTGCCGCCAGCCCTATCGACAGTGCCGCATCA
TGCCGTTACTGGCCGATCTGGAGCAGGCGCAGGATGCGGGCGACATCGATCGTGAGGCGTTGCTGCGTGCTTTTCGCGAC
TATCTGGAAGCCCATAATCTGGAAGCCGATTGGGAAAGTATCGCGCGGGCGGGCAATGAAACGCTGGTCAATGCGTTTTC
TATCATGTCGCCTTTCGGCCCTGCGGAAAAACAGGCGCTGTTGGAGGCACCCGACCTGAAAACCCGCGCCGCCACGCTGA
TCGCCATTACCGAAATGGTGCTGGCCAAGGTGAAAGACGATGATTTTGGCTCGCGCCTGCAATAG

Upstream 100 bases:

>100_bases
TGCACGCCGCAAATTGTCGTCGCTCCTGTTTTCGTGATTTCCGAAAGAGGCCGACTGTCGTTGGGGATGGGTCTCGAACG
GTGATGCTGAGGAGGTTATG

Downstream 100 bases:

>100_bases
AGTATTTTCGAGCCAAAGGTGCGAAGCGCCTGCGCGGGGAAATCAGTCCACTGGACGGATTTCTGATCCCGCTTCGATGC
ATCGGATAATGCGTAAAGAC

Product: peptidase S16 lon domain-containing protein

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MQVGNARYRTAADIPDVVPVFPLKGALLLPGGQLPLNIFEPRYLSMVENALAGKRIIGMIQPKIDSETDDTDEPVDALDE
SLRPELSQVGCLGRITTFAEIGDGRLLITLQGICRFRVQEELHCRQPYRQCRIMPLLADLEQAQDAGDIDREALLRAFRD
YLEAHNLEADWESIARAGNETLVNAFSIMSPFGPAEKQALLEAPDLKTRAATLIAITEMVLAKVKDDDFGSRLQ

Sequences:

>Translated_234_residues
MQVGNARYRTAADIPDVVPVFPLKGALLLPGGQLPLNIFEPRYLSMVENALAGKRIIGMIQPKIDSETDDTDEPVDALDE
SLRPELSQVGCLGRITTFAEIGDGRLLITLQGICRFRVQEELHCRQPYRQCRIMPLLADLEQAQDAGDIDREALLRAFRD
YLEAHNLEADWESIARAGNETLVNAFSIMSPFGPAEKQALLEAPDLKTRAATLIAITEMVLAKVKDDDFGSRLQ
>Mature_234_residues
MQVGNARYRTAADIPDVVPVFPLKGALLLPGGQLPLNIFEPRYLSMVENALAGKRIIGMIQPKIDSETDDTDEPVDALDE
SLRPELSQVGCLGRITTFAEIGDGRLLITLQGICRFRVQEELHCRQPYRQCRIMPLLADLEQAQDAGDIDREALLRAFRD
YLEAHNLEADWESIARAGNETLVNAFSIMSPFGPAEKQALLEAPDLKTRAATLIAITEMVLAKVKDDDFGSRLQ

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 25946; Mature: 25946

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVGNARYRTAADIPDVVPVFPLKGALLLPGGQLPLNIFEPRYLSMVENALAGKRIIGMI
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QPKIDSETDDTDEPVDALDESLRPELSQVGCLGRITTFAEIGDGRLLITLQGICRFRVQE
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
ELHCRQPYRQCRIMPLLADLEQAQDAGDIDREALLRAFRDYLEAHNLEADWESIARAGNE
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCH
TLVNAFSIMSPFGPAEKQALLEAPDLKTRAATLIAITEMVLAKVKDDDFGSRLQ
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQVGNARYRTAADIPDVVPVFPLKGALLLPGGQLPLNIFEPRYLSMVENALAGKRIIGMI
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QPKIDSETDDTDEPVDALDESLRPELSQVGCLGRITTFAEIGDGRLLITLQGICRFRVQE
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
ELHCRQPYRQCRIMPLLADLEQAQDAGDIDREALLRAFRDYLEAHNLEADWESIARAGNE
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCH
TLVNAFSIMSPFGPAEKQALLEAPDLKTRAATLIAITEMVLAKVKDDDFGSRLQ
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA