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The map label for this gene is hsdS [H]

Identifier: 225686603

GI number: 225686603

Start: 803518

End: 804741

Strand: Direct

Name: hsdS [H]

Synonym: BMEA_B0820

Alternate gene names: 225686603

Gene position: 803518-804741 (Clockwise)

Preceding gene: 225686602

Following gene: 225686604

Centisome position: 67.78

GC content: 52.61

Gene sequence:

>1224_bases
ATGTCGGTTGAAGTGCCCAAAGGCTGGCGCGAGGTGCGCATCGGTCAAATTGCCCGCGAAATCTCGAATAGAAACCATGC
GAGCGCTGACATCCCCGTCCTAAGCATGACAAAGCACCGGGGTTTTGTCCGTTCCAATGAGTATTTCTCAAAGTCCGTTC
ATAGTGAGAACACCCGCCAATACAAGGTTGTGAAGCGTGGGCAATTTGCCTACGCCACGATCCACCTTGATGAAGGTTCT
ATTGACTACCTGAGAAACGAGGACGCGGGCTTGATTAGCCCGATGTATACGGTTTTCGAAACCAATTCCGAAGAGATCAA
CAATGAAATTGCGCTTCGGCAGTTCAAAAGATTTGCGCTGAGTGGTCGTTTCGACCCCTACAGCAATGGCGGGGTCAATC
GCAGAAAATCCATCCTATTCAGCGATCTGTCCGCCTTCAAATTCGGGCTGCCTCCGCTCACGGAACAGCGCGCGATTGCA
GAAGTCCTCGGCGCTGCCGAGGCCGCTATTGCGAAGACTGAGGCGCTAATCAAGGCGATTGAGCAAACCAAGAAAGCGCT
TCTCAAACAGTATTTTGTCGAACGACAGCAGTCTCTGCTTTGGTCCTGCGTAGCGAAGATGGGGCGCTGGCTGAGCGGAG
GAACGCCTGCAACTGCGGCTGAGGAGAACTGGAAAGGATCAATACCTTGGGTGTGTCCGAAAGATATAAAAGGTCCAAGT
ATTTCATCGACGGTAGACCACATTTCGGAAGACGCGGCAAAAGCGCTCGGGATGGTTGGTCCGGGAACGCTTCTCTTGGT
CGTTCGCGGCATGATCCTTGCGCGATCAGTCCCTTCAACGATCTGCACAGTTCGGTGTGCTTTCAATCAGGACGTGAAAG
CATTTGTTCCCAATGAAGGTGTTGCACCGGCGTTTCTAAAACTCTGGCTCGACATAAATGAGCACAAGCTTCTGGGAGAG
ATAGAGACTGCCACACATGGAACCAAGCGGTTTCCTTTGGAGCGCCTTAACGAATTTCCCGTCCCCGTCGTAACGCGCGA
CGAGCAAATCAGATTGGTCACATTAGCTGAAAGTAGCCAAGAGCGCTTGCGTTCAGAGAGAGACAACCTCTCTGCGCTTC
GTTCTGTACGGGATGCGTTAGCTCAGGAACTGCTCTCAGGGCGCATTCGCCTCCCTGAAAGCATTATTGCGCGGCATCGT
GACAAAGCTGGGCAAGCTGCATGA

Upstream 100 bases:

>100_bases
CCGATCGATGTGCAGGCCGAACTTGCCAAGCTGTGGGACGCTGAGACGGCCCGGGACGAAGCTGCGGCCCGCATGAACGC
CCTTCTCAAGGAGATGGGTT

Downstream 100 bases:

>100_bases
ACGAGACTAGTGAACAGCTTGAGCGCGAATGGGTAGAGGAGCCGGCGACGGACCTGCTGCGGGTGCTGTTCGACTATAAG
CCCCTGTCACCAGAGGACGT

Product: type I restriction enzyme specificity protein

Products: NA

Alternate protein names: S.EcoR124II; Type I restriction enzyme EcoR124II specificity protein; S protein [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSVEVPKGWREVRIGQIAREISNRNHASADIPVLSMTKHRGFVRSNEYFSKSVHSENTRQYKVVKRGQFAYATIHLDEGS
IDYLRNEDAGLISPMYTVFETNSEEINNEIALRQFKRFALSGRFDPYSNGGVNRRKSILFSDLSAFKFGLPPLTEQRAIA
EVLGAAEAAIAKTEALIKAIEQTKKALLKQYFVERQQSLLWSCVAKMGRWLSGGTPATAAEENWKGSIPWVCPKDIKGPS
ISSTVDHISEDAAKALGMVGPGTLLLVVRGMILARSVPSTICTVRCAFNQDVKAFVPNEGVAPAFLKLWLDINEHKLLGE
IETATHGTKRFPLERLNEFPVPVVTRDEQIRLVTLAESSQERLRSERDNLSALRSVRDALAQELLSGRIRLPESIIARHR
DKAGQAA

Sequences:

>Translated_407_residues
MSVEVPKGWREVRIGQIAREISNRNHASADIPVLSMTKHRGFVRSNEYFSKSVHSENTRQYKVVKRGQFAYATIHLDEGS
IDYLRNEDAGLISPMYTVFETNSEEINNEIALRQFKRFALSGRFDPYSNGGVNRRKSILFSDLSAFKFGLPPLTEQRAIA
EVLGAAEAAIAKTEALIKAIEQTKKALLKQYFVERQQSLLWSCVAKMGRWLSGGTPATAAEENWKGSIPWVCPKDIKGPS
ISSTVDHISEDAAKALGMVGPGTLLLVVRGMILARSVPSTICTVRCAFNQDVKAFVPNEGVAPAFLKLWLDINEHKLLGE
IETATHGTKRFPLERLNEFPVPVVTRDEQIRLVTLAESSQERLRSERDNLSALRSVRDALAQELLSGRIRLPESIIARHR
DKAGQAA
>Mature_406_residues
SVEVPKGWREVRIGQIAREISNRNHASADIPVLSMTKHRGFVRSNEYFSKSVHSENTRQYKVVKRGQFAYATIHLDEGSI
DYLRNEDAGLISPMYTVFETNSEEINNEIALRQFKRFALSGRFDPYSNGGVNRRKSILFSDLSAFKFGLPPLTEQRAIAE
VLGAAEAAIAKTEALIKAIEQTKKALLKQYFVERQQSLLWSCVAKMGRWLSGGTPATAAEENWKGSIPWVCPKDIKGPSI
SSTVDHISEDAAKALGMVGPGTLLLVVRGMILARSVPSTICTVRCAFNQDVKAFVPNEGVAPAFLKLWLDINEHKLLGEI
ETATHGTKRFPLERLNEFPVPVVTRDEQIRLVTLAESSQERLRSERDNLSALRSVRDALAQELLSGRIRLPESIIARHRD
KAGQAA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 45339; Mature: 45208

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEVPKGWREVRIGQIAREISNRNHASADIPVLSMTKHRGFVRSNEYFSKSVHSENTRQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHCCCCCCE
YKVVKRGQFAYATIHLDEGSIDYLRNEDAGLISPMYTVFETNSEEINNEIALRQFKRFAL
EHEEECCCEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SGRFDPYSNGGVNRRKSILFSDLSAFKFGLPPLTEQRAIAEVLGAAEAAIAKTEALIKAI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTKKALLKQYFVERQQSLLWSCVAKMGRWLSGGTPATAAEENWKGSIPWVCPKDIKGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ISSTVDHISEDAAKALGMVGPGTLLLVVRGMILARSVPSTICTVRCAFNQDVKAFVPNEG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCEEECCCCC
VAPAFLKLWLDINEHKLLGEIETATHGTKRFPLERLNEFPVPVVTRDEQIRLVTLAESSQ
CCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEECCCCEEEEEECCCHH
ERLRSERDNLSALRSVRDALAQELLSGRIRLPESIIARHRDKAGQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVEVPKGWREVRIGQIAREISNRNHASADIPVLSMTKHRGFVRSNEYFSKSVHSENTRQ
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHCCCCCCE
YKVVKRGQFAYATIHLDEGSIDYLRNEDAGLISPMYTVFETNSEEINNEIALRQFKRFAL
EHEEECCCEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SGRFDPYSNGGVNRRKSILFSDLSAFKFGLPPLTEQRAIAEVLGAAEAAIAKTEALIKAI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTKKALLKQYFVERQQSLLWSCVAKMGRWLSGGTPATAAEENWKGSIPWVCPKDIKGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ISSTVDHISEDAAKALGMVGPGTLLLVVRGMILARSVPSTICTVRCAFNQDVKAFVPNEG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCEEECCCCC
VAPAFLKLWLDINEHKLLGEIETATHGTKRFPLERLNEFPVPVVTRDEQIRLVTLAESSQ
CCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEECCCCEEEEEECCCHH
ERLRSERDNLSALRSVRDALAQELLSGRIRLPESIIARHRDKAGQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]