| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
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The map label for this gene is xseA [H]
Identifier: 225686532
GI number: 225686532
Start: 724080
End: 725615
Strand: Reverse
Name: xseA [H]
Synonym: BMEA_B0742
Alternate gene names: 225686532
Gene position: 725615-724080 (Counterclockwise)
Preceding gene: 225686538
Following gene: 225686529
Centisome position: 61.21
GC content: 64.26
Gene sequence:
>1536_bases ATGGCCTCCGATTCGAGTTTTCCCGGCGCATCGTCGAATGTGGCCGAGTATAGCGTGTCCGAGATTTCCGGCGCTTTGAA GCGCACGGTTGAGGACACGTTCGGCCATGTGCGTGTGCGCGGCGAGATTTCCGGCTATCGCGGCCCGCATTCTTCCGGCC ATGCCTATTTTGCGCTGAAGGATGACCGTGCCCGGCTTGAAGCCGTGATCTGGCGCGGCTCGATGAGCCGCCTTCGCTTC CGCCCCGAAGAGGGCATGGAGGTGATCGCCACCGGCAAGCTCACCACCTATCCCGGTTCATCCAAATATCAGATCGTCAT CGAGCAGATGGAACCCGCCGGCGCGGGCGCGCTGATGGCGCTTCTGGAGGAGCGCAAGCAGCGCCTGGCGGCAGAAGGCC TGTTCGATCCTGCCCTGAAACAGCTTCTGCCCTTCATGCCGCGCGTCATCGGCGTGGTGACATCTCCCACCGGCGCGGTC ATCCGCGATATCATCCATCGCATTTCCGATCGTTATCCGCTGCGCGTGATCGTCTGGCCGGTGCGCGTGCAGGGCGATAC CTGCGGGCCTGAAGTGGCAACGGCGGTGAACGGCTTCAACACCCTGCCGGATGACGGCCCCATTCCGCGCCCCGATGTGC TGATCGTGGCGCGCGGCGGCGGCAGTCTGGAAGATCTCTGGGGCTTTAACGATGAAATCGTCGTGCGGGCGGTCGCAGCT TCCCATATTCCCGTTATCTCGGCGGTCGGGCATGAAACCGACTGGACGCTGATAGATCTTGCCGCCGACATGCGCGCGCC GACTCCCACCGGTGCTGCGGAAATGGCGGTGCCGGTGAAGGCTGATCTTCAGGCCTCACTTGCCAGCCAGTCGGCGCGGC TTTCTTCCGCCATGTCGCGCTTTTTCGACCAGAAGCGACAGGCGCATCGTGCTGCCGCGCGCGCCATGCCCTCTGCCGAC CAGTTGCTGGCCCTGCCGCGCCGCCGGTTCGATGAAGCGGCCTCGCGGCTTACCCGCGCACTTTTCGTCAATACGCAGAA AAAGCGCGTCCATTTCGATGGTCATGCCCGGCAATTGTCGCCCCGGCTTTTACAGCGGCGGCTTGTGGAGCTGGAACGCG GTGTGACGATGCTGGGCCAGCGCCTGCCGCGCGCGCTGGAAGCCTTTCTGCGCGAGCGCCGGACGGCTTTCACCCATCGC GCCAACCGGCTTTCGCCGGAACCCATATTGCGCCGCACACGGCTGACGGGCTCGACCCTCGAACAGCTCGACCGCCGCCG CGATCAGGCCGTGCGGCTTCTGATCGAGCGTGTGAAGCGGCGCAGTCAAGAACTCGACCGGTTGATGCGCACGCTTTCTT ATGAAAGCGTGCTGGAACGCGGCTTTGCTGTTGTATTCGATGCGCAGGGCAAGCCCGTCAAGCAGGCGGCGGCTGTGTCG CCAGGCGATGCGCTGTCTATCCGGTTCCGCGACGGTGATGTCGGGGTTGTCGCGCGCGCGGGGCTCACAATCCCCGATCC GACCAAAGGCCAGTAA
Upstream 100 bases:
>100_bases TGCACACCAATGAATTGTTGCCCGGCTGGTGAACAGTGCGTAATTCGCCGCGCGGCTGCTTGACCGCCTGCGCCCACTGG TAGCCTATAACGGGATGAGC
Downstream 100 bases:
>100_bases GTCTCAAGCTGAAAAAAGGCGCGATCATCGCGCCCTTTTCCATTTTGTGACATCGGAACGCTTCTTCAATAGGCATATTC GAGGAAGATCGGATCCACCG
Product: exodeoxyribonuclease VII large subunit
Products: NA
Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]
Number of amino acids: Translated: 511; Mature: 510
Protein sequence:
>511_residues MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRF RPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAV IRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSAD QLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHR ANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS PGDALSIRFRDGDVGVVARAGLTIPDPTKGQ
Sequences:
>Translated_511_residues MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRF RPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAV IRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSAD QLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHR ANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS PGDALSIRFRDGDVGVVARAGLTIPDPTKGQ >Mature_510_residues ASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFR PEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVI RDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAAS HIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQ LLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRA NRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVSP GDALSIRFRDGDVGVVARAGLTIPDPTKGQ
Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]
COG id: COG1570
COG function: function code L; Exonuclease VII, large subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the xseA family [H]
Homologues:
Organism=Escherichia coli, GI1788856, Length=487, Percent_Identity=35.9342915811088, Blast_Score=259, Evalue=3e-70,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003753 - InterPro: IPR020579 - InterPro: IPR004365 [H]
Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]
EC number: =3.1.11.6 [H]
Molecular weight: Translated: 56347; Mature: 56216
Theoretical pI: Translated: 10.87; Mature: 10.87
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALK CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEC DDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMA CCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCEEECCCCCCEEEEEEECCCCCHHHHHH LLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWP HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEE VRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA EEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSR CCCCEEHCCCCCCCCEEEEEHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH FFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLS HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHCC PRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH EQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCC PGDALSIRFRDGDVGVVARAGLTIPDPTKGQ CCCEEEEEEECCCEEEEEECCCCCCCCCCCC >Mature Secondary Structure ASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALK CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEC DDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMA CCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCEEECCCCCCEEEEEEECCCCCHHHHHH LLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWP HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEE VRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA EEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSR CCCCEEHCCCCCCCCEEEEEHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH FFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLS HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHCC PRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH EQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCC PGDALSIRFRDGDVGVVARAGLTIPDPTKGQ CCCEEEEEEECCCEEEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA