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The map label for this gene is aaeA [H]

Identifier: 225686526

GI number: 225686526

Start: 717870

End: 718736

Strand: Reverse

Name: aaeA [H]

Synonym: BMEA_B0736

Alternate gene names: 225686526

Gene position: 718736-717870 (Counterclockwise)

Preceding gene: 225686527

Following gene: 225686525

Centisome position: 60.63

GC content: 58.13

Gene sequence:

>867_bases
ATGAAAAAGCTCCTTGCACATTCCGGCCGGGTTTTTCTCACCCTCGTCATGGTTGTTATGGCGGGGCTGCTCGGCTGGCA
TCTCTGGGATTATTACATGAATGCGCCGTGGACCCGTGACGGCAAAATCCGTGCCGATGTGGTGCGCATTGCGCCCGATG
TCTCGGGCCTTGTGAGCGAGGTTCTGGTGCATGACAACCAGACGGTCCATAAAGGCGATGTGATTTTCCGCATCGACCAG
GCGCGCTACAAGCTTGCTTTGCAGACTGCTGAGGCCAAGGCTGACAGCAGCAAGGCAGCACTGGACATGGCCAATCGTGA
TCTTGTCCGCTATCGCCAGCTCAACGATACGACCGTGACGCGCCAGAAACTGGAACAGGTAGAAACCGCAGCCCAGCAGG
CAGAGGCCGCCCACCGCCAGGCCGAACTCGACCGCGATCTGGCTGCGCTTAATATGGAGCGTTCGTCTATCAAGGCTCCG
GTCAATGGCGTTATCACCAATTTCTCGCTTCAGCCGGGCGATTATGTTTCGGCGGGTTCGGCCGTTACGGCGCTGGTCGA
TACGGATTCCTATTATGTCTCCGGTTATTTTGAGGAAAACAAGCTGGAGCGTATCCATATCGGTGATCCGGTGGTGGTCG
ATGTGATGGGCAGCAAGGTGCAGCTCAAGGGTAAGGTGGAAGGTATTGCGGGCGGCATCGAGGATCGCGAGCGCAGCGAT
TCCCAAAGCCTGCTCGCCAATGTCTCGCCGACGTTCAACTGGGTGCGCCTTGCGCAGCGCGTGCCGGTGCGTGTGAAACT
GGAAGATGTGCCGCAAGGCATCCATCTGGTGGCAGGCCGCACGGTGAGCGTTTCGGTGGTGGATTGA

Upstream 100 bases:

>100_bases
TGCATTTCTACCGTTTTGTGTGGCATCGCCCGCTTTTCGATGCCGCCATGTATTTCTGCATTCTCGGCGTTGCTGCCGTC
CTCTTGAATGGAATCCCCCT

Downstream 100 bases:

>100_bases
TGGCCCGGCCGCGCTACTGGCGGGCATGCTACCAGAATAGCTCCGGTTAAAACGGTATCGCCTCTCTTATCTTGGGGGCA
AGGGAATGGCTGCCGCGCTT

Product: p-hydroxybenzoic acid efflux pump subunit aaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKLEDVPQGIHLVAGRTVSVSVVD

Sequences:

>Translated_288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKLEDVPQGIHLVAGRTVSVSVVD
>Mature_288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKLEDVPQGIHLVAGRTVSVSVVD

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=279, Percent_Identity=40.1433691756272, Blast_Score=213, Evalue=9e-57,
Organism=Escherichia coli, GI1789637, Length=286, Percent_Identity=38.1118881118881, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1790519, Length=289, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789041, Length=301, Percent_Identity=25.5813953488372, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788711, Length=315, Percent_Identity=25.7142857142857, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790024, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082036, Length=215, Percent_Identity=26.5116279069767, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790012, Length=313, Percent_Identity=23.6421725239617, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 31777; Mature: 31777

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHH
VLVHDNQTVHKGDVIFRIDQARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVT
HHHCCCCEEECCCEEEEECCHHEEEEEEHHHCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
RQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAPVNGVITNFSLQPGDYVSAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCCCC
AVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
EEEEEEECCCEEEEEEEECCCCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCC
SQSLLANVSPTFNWVRLAQRVPVRVKLEDVPQGIHLVAGRTVSVSVVD
HHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEEEC
>Mature Secondary Structure
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHH
VLVHDNQTVHKGDVIFRIDQARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVT
HHHCCCCEEECCCEEEEECCHHEEEEEEHHHCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
RQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAPVNGVITNFSLQPGDYVSAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCCCC
AVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
EEEEEEECCCEEEEEEEECCCCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCC
SQSLLANVSPTFNWVRLAQRVPVRVKLEDVPQGIHLVAGRTVSVSVVD
HHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA