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The map label for this gene is putA [H]

Identifier: 225686494

GI number: 225686494

Start: 682626

End: 686309

Strand: Reverse

Name: putA [H]

Synonym: BMEA_B0697

Alternate gene names: 225686494

Gene position: 686309-682626 (Counterclockwise)

Preceding gene: 225686496

Following gene: 225686493

Centisome position: 57.89

GC content: 61.26

Gene sequence:

>3684_bases
ATGACCGATAATATTTCTGTTTCCAAAGTGGCCGTTTTCCAGAATTTTGCGCCGCCGATCCGCGAGCAAAGCGCACTGAG
GCAAGCGATCACTGCCGCTTATCGCCGCCCCGAAGCCGAATGCGTTTCAGCGCTGGCCGAGCAGGCAACCTTGCCGGAGG
AGACGCGCCAGCAAATCCGTTCCACCGCCCGCAAGCTGATCGAAGCGCTGCGTGCCAAGCATAAGGGCACCGGCATCGAA
GGTCTGGTGCATGAATATTCGCTGTCGAGCCAGGAAGGCGTGGCGCTGATGTGCCTTGCCGAAGCCTTGCTGCGCATTCC
CGATATGGCGACGCGCGATGCGCTGATCCGCGACAAGATATCGAATGGCGACTGGAAATCCCACATTGGCGGCGGGCGCT
CGCTTTTCGTCAATGCTGCGACATGGGGCCTGGTCGTTACCGGCAAGCTCACCAATACCGTCAATGATCGTGGCCTTTCC
GCCGCTCTTACCCGCCTCATCGCCCGCTGCGGCGAGCCGGTCATCCGTCGCGGCGTGGACATGGCCATGCGCATGATGGG
CGAGCAGTTCGTCACCGGCGAAACCATCGATGAGGCGTTGAAACGCGCCAAGGAGCTGGAAGAGCGCGGCTTCCGCTATT
CCTACGACATGCTGGGCGAGGCCGCGACCACCGCCGCCGATGCAGAGCGTTATTATAAGGATTATGAAACCGCGATCCAC
GCCATCGGTCGTGCTTCCGCAGGGCGCGGCATTTATGATGGTCCCGGCATTTCCATCAAGCTTTCGGCGCTTCACCCGCG
TTATACCCGCGCGCAAAGTGAGCGCGTCATGGGTGAACTTCTGCCGAAGGTGAAGGCACTCGCGGCCATCGCCAAGTCCT
ATAATATCGGCCTCAATATCGACGCGGAGGAGGCCGACCGTCTTGAACTGTCGCTCGACCTGTTGCAAAGCCTTTGCGAA
GACCCTGATCTGGCAGGCTGGGATGGCATCGGCTTCGTGGTGCAGGCCTATGGCAAGCGCTGCCCCCTCGTGCTTGATTT
CATCATCGATCTGGCTCGCCGCACCAAGCGCCGCGTCATGGTGCGTCTGGTGAAGGGCGCCTATTGGGATGCGGAGATCA
AGCGTGCGCAGGTGGATGGGCTGGAGGATTTTCCGGTCTATACCCGCAAGGTGCATACGGACGTTTCCTATATTGCCTGC
GCGCGCAAGCTTCTGGCCGCGACGGATGTGATCTTTCCGCAATTTGCGACCCATAACGCGCAGACACTCGCCACGATCTA
TCATCTGGCCGGGCCGGATTTCAAAACCGGTAAGTTTGAGTTCCAATGCCTGCACGGCATGGGTGAGCCGCTTTATGATG
AAGTCGTCGGCCCCGAAAAGCTCGGTCGCCCGGCCCGCATTTATGCACCGGTCGGCACGCATGAAACGCTGCTCGCCTAT
CTCGTCCGCCGCCTTCTTGAAAACGGCGCGAACTCCTCCTTCGTCAACCGTATTGGCGACAAAAACGTCTCGGTCGATGA
GCTGATCGCCGATCCGGTGGAAGTCGTCCGGTCGATGGCTGTCGTCGGTGCGCGTCATGACCAGATTGCGCTGCCGGAAA
ATCTCTATGGCGCGCGCCGCAATTCCGCAGGCTTTGATCTTTCCAATGAGGTGACGCTTGCGGAACTGAGCAAAACCTTG
AAGGAAACGGCAGGCCGTGCATGGACCGCCGAACCGCAGGTGGCGGGTGCAAAGGTGAAGGGCGTAAGCCGTCCGGTTCT
CAATCCCGGCGACCGGAATGATGTTGTCGGCACCGTAACGGAAATCGCAGAGGCCGATGTGGCAAAGGCGATGAAGGCAG
CGCAAACCGCGACCACAAGCTGGTCCGCGGTTGCGCCCGCAGAACGCGCCGCCTGTCTGGAGCGCGCAGCCGATATCATG
CAGCGCGACATGCCGGCTCTGCTCGGCCTCGTCATGCGCGAGGCAGGCAAGTCCATGCCGAACGCCATTGCCGAAGTGCG
TGAAGCCATCGATTTCCTGCGCTATTATGCCGAACAGACCCGCCGCACGCTTGGCGTCGGCCACAAGGCGCTTGGCCCTG
TCGTCTGCATCAGCCCGTGGAACTTCCCGCTGGCAATCTTCACCGGCCAGATTGCGGCTGCACTTGTTGCAGGCAATCCG
GTTCTGGCAAAGCCTGCCGAGGAAACCCCGCTGATCGCCGCTGAGGGCGTGCGCATTCTGCATGAGGGGGGCATTCCGGC
GGATGCGCTCCAGCTTCTGCCGGGTGATGGCCGCATTGGCGCCGCGCTGGTTGCAGCACCGGAAACTTGCGGCGTAATGT
TCACCGGCTCCACCGAGGTGGCGCGGCTCATCCAGGCGCAGCTTGCCTCGCGCCTGCTGCCGAACGGAAAGCCGGTCCCG
CTCATTGCCGAAACGGGCGGTCAGAACGCCATGATCGTGGATTCCTCGGCACTTGCCGAGCAGGTGGTGTTTGATGTCAT
CGCTTCGGCTTTCGATAGCGCCGGCCAGCGCTGTTCGGCGCTGCGTGTCCTCTGCTTGCAGGAAGATGTGGCCGACCGCA
TTCTCACCATGCTCAAGGGCGCCTTGCGTGAGCTTTCCATTGGCCGCACGGACCAGCTCAAGGTCGATATCGGCCCGGTT
ATCACCGATGAGGCGAAGAACACCATTGAAAAGCATATTCAGGCCATGCGCGATCTTGGCCGCAAGGTGGAACAGCTTCC
CCTTGGCCCGGAAACGCAGAACGGCACTTTTGTTGCGCCGACAATCATCGAGATTGAATCGCTGCGCGATCTCAAGCGCG
AAGTGTTCGGCCCGGTCCTGCATGTGGTTCGTTACAAGCGCGACGAAATGGAAAGCCTGATCGATGATATCAATTCGACC
GGCTATGGGCTTACTTTTGGTTTGCATACGCGCCTTGACGAGACGATTGCCAATGTTGCGGATCGCATCCGTGTCGGCAA
TATCTATATCAATCGCAACATTATCGGCGCAGTGGTGGGCGTGCAGCCTTTCGGCGGGCGTGGCCTTTCCGGCACCGGCC
CGAAGGCGGGCGGTCCGCTCTATCTTGGCCGTCTGGTCGAAACCGCGCCGATCCCGCCGCGTCACGCTTCGGTTCATACC
GATGCGGCGCTGAAGGACTTTGCCCGGTGGCTCGGCAATCGCGGCATGAACGATCTGGCGCAGGCGGCGCGCGATACCGG
CAGTGCTTCGGCGCTCGGTCTCGAACTCGAACTGCCGGGCCCGGTTGGCGAGCGCAATCTCTATGCTCTCCACCCGCGCG
GGCGCGTGCTTCTGGTCCCCCAGACCGAAATTGGCCTCTATCGCCAATTGACGGCGGTGCTGGCAACCGGCAACACTGCG
GTCATCGACGAGGCTTGCGGTTTGCGCGCCGTGTTGAAGGATCTGCCGGAAACAGTTGCCGCGCGCGCCATCTGGACGGG
CGACTGGCAGGCGGATGCGCCTTTTGCCGGAGCACTTATCGAAGGCGACAGCGCGCGCATCAAGGAGGTGAACTCCAGGA
TCGCCGCCCTGCCGGGACCGCTCGTACTCACACAGGCGGCATCGCCGGAAGATCTTGCAGCCAATCAGGATGCTTATTGC
CTCAACTGGCTGCTTGAGGAAGTCTCGACCTCCATCAACACCACGGCAGCAGGCGGCAACGCCAGCCTGATGGCGATCGG
CTGA

Upstream 100 bases:

>100_bases
GCAGAATGGAATTTATGCGGATGATAATGTGCAACTAAATTAAAGAAGGGCTATCCTTGAGTGACATCTGGGGCCTTTTC
CTTTTTGTGAGCAGTGCACC

Downstream 100 bases:

>100_bases
TTTCTTCGCATATGTGAGGCAGAAAAGGCGGCTTTCCGGCCGCCTTTTCTTTGCGCCACGCAAGGCTTGCATGGCTGTGC
AGAAAAATCGACAACAGAAC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1227; Mature: 1226

Protein sequence:

>1227_residues
MTDNISVSKVAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIRSTARKLIEALRAKHKGTGIE
GLVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKISNGDWKSHIGGGRSLFVNAATWGLVVTGKLTNTVNDRGLS
AALTRLIARCGEPVIRRGVDMAMRMMGEQFVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIH
AIGRASAGRGIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNIDAEEADRLELSLDLLQSLCE
DPDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVMVRLVKGAYWDAEIKRAQVDGLEDFPVYTRKVHTDVSYIAC
ARKLLAATDVIFPQFATHNAQTLATIYHLAGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAY
LVRRLLENGANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARRNSAGFDLSNEVTLAELSKTL
KETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVTEIAEADVAKAMKAAQTATTSWSAVAPAERAACLERAADIM
QRDMPALLGLVMREAGKSMPNAIAEVREAIDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNP
VLAKPAEETPLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEVARLIQAQLASRLLPNGKPVP
LIAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSALRVLCLQEDVADRILTMLKGALRELSIGRTDQLKVDIGPV
ITDEAKNTIEKHIQAMRDLGRKVEQLPLGPETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDEMESLIDDINST
GYGLTFGLHTRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVETAPIPPRHASVHT
DAALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPGPVGERNLYALHPRGRVLLVPQTEIGLYRQLTAVLATGNTA
VIDEACGLRAVLKDLPETVAARAIWTGDWQADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYC
LNWLLEEVSTSINTTAAGGNASLMAIG

Sequences:

>Translated_1227_residues
MTDNISVSKVAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIRSTARKLIEALRAKHKGTGIE
GLVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKISNGDWKSHIGGGRSLFVNAATWGLVVTGKLTNTVNDRGLS
AALTRLIARCGEPVIRRGVDMAMRMMGEQFVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIH
AIGRASAGRGIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNIDAEEADRLELSLDLLQSLCE
DPDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVMVRLVKGAYWDAEIKRAQVDGLEDFPVYTRKVHTDVSYIAC
ARKLLAATDVIFPQFATHNAQTLATIYHLAGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAY
LVRRLLENGANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARRNSAGFDLSNEVTLAELSKTL
KETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVTEIAEADVAKAMKAAQTATTSWSAVAPAERAACLERAADIM
QRDMPALLGLVMREAGKSMPNAIAEVREAIDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNP
VLAKPAEETPLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEVARLIQAQLASRLLPNGKPVP
LIAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSALRVLCLQEDVADRILTMLKGALRELSIGRTDQLKVDIGPV
ITDEAKNTIEKHIQAMRDLGRKVEQLPLGPETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDEMESLIDDINST
GYGLTFGLHTRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVETAPIPPRHASVHT
DAALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPGPVGERNLYALHPRGRVLLVPQTEIGLYRQLTAVLATGNTA
VIDEACGLRAVLKDLPETVAARAIWTGDWQADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYC
LNWLLEEVSTSINTTAAGGNASLMAIG
>Mature_1226_residues
TDNISVSKVAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIRSTARKLIEALRAKHKGTGIEG
LVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKISNGDWKSHIGGGRSLFVNAATWGLVVTGKLTNTVNDRGLSA
ALTRLIARCGEPVIRRGVDMAMRMMGEQFVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIHA
IGRASAGRGIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNIDAEEADRLELSLDLLQSLCED
PDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVMVRLVKGAYWDAEIKRAQVDGLEDFPVYTRKVHTDVSYIACA
RKLLAATDVIFPQFATHNAQTLATIYHLAGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAYL
VRRLLENGANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARRNSAGFDLSNEVTLAELSKTLK
ETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVTEIAEADVAKAMKAAQTATTSWSAVAPAERAACLERAADIMQ
RDMPALLGLVMREAGKSMPNAIAEVREAIDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNPV
LAKPAEETPLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEVARLIQAQLASRLLPNGKPVPL
IAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSALRVLCLQEDVADRILTMLKGALRELSIGRTDQLKVDIGPVI
TDEAKNTIEKHIQAMRDLGRKVEQLPLGPETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDEMESLIDDINSTG
YGLTFGLHTRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVETAPIPPRHASVHTD
AALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPGPVGERNLYALHPRGRVLLVPQTEIGLYRQLTAVLATGNTAV
IDEACGLRAVLKDLPETVAARAIWTGDWQADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYCL
NWLLEEVSTSINTTAAGGNASLMAIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=449, Percent_Identity=30.9576837416481, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI21361176, Length=458, Percent_Identity=31.0043668122271, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI25777736, Length=534, Percent_Identity=29.9625468164794, Blast_Score=171, Evalue=5e-42,
Organism=Homo sapiens, GI25777734, Length=534, Percent_Identity=29.9625468164794, Blast_Score=171, Evalue=5e-42,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=30.7522123893805, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238859541, Length=475, Percent_Identity=30.1052631578947, Blast_Score=167, Evalue=8e-41,
Organism=Homo sapiens, GI25777730, Length=454, Percent_Identity=30.6167400881057, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI25777732, Length=453, Percent_Identity=28.9183222958057, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI12007648, Length=445, Percent_Identity=28.314606741573, Blast_Score=160, Evalue=8e-39,
Organism=Homo sapiens, GI25777728, Length=407, Percent_Identity=30.4668304668305, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI4507229, Length=450, Percent_Identity=27.7777777777778, Blast_Score=144, Evalue=6e-34,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=28.3687943262411, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI238814322, Length=419, Percent_Identity=27.4463007159904, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI25777721, Length=463, Percent_Identity=26.9978401727862, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25777726, Length=451, Percent_Identity=28.3813747228381, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25952152, Length=439, Percent_Identity=27.3348519362187, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI115387104, Length=444, Percent_Identity=26.1261261261261, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI11095441, Length=428, Percent_Identity=26.4018691588785, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310128093, Length=449, Percent_Identity=26.0579064587973, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI310128103, Length=452, Percent_Identity=25.8849557522124, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI188035924, Length=452, Percent_Identity=25.8849557522124, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI310128091, Length=394, Percent_Identity=26.6497461928934, Blast_Score=105, Evalue=4e-22,
Organism=Homo sapiens, GI310128087, Length=302, Percent_Identity=26.8211920529801, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI206597441, Length=442, Percent_Identity=24.6606334841629, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI206597439, Length=442, Percent_Identity=24.6606334841629, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI22907049, Length=442, Percent_Identity=24.6606334841629, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI4502043, Length=347, Percent_Identity=25.6484149855908, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI238814371, Length=347, Percent_Identity=25.6484149855908, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI71773324, Length=347, Percent_Identity=25.6484149855908, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI301500698, Length=266, Percent_Identity=28.1954887218045, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI73695881, Length=350, Percent_Identity=24.5714285714286, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73695879, Length=350, Percent_Identity=24.5714285714286, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=25.2279635258359, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI4557303, Length=334, Percent_Identity=23.3532934131737, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI73466520, Length=334, Percent_Identity=23.3532934131737, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI310128095, Length=247, Percent_Identity=25.9109311740891, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI310128099, Length=217, Percent_Identity=26.2672811059908, Blast_Score=72, Evalue=4e-12,
Organism=Homo sapiens, GI310128101, Length=217, Percent_Identity=26.2672811059908, Blast_Score=72, Evalue=4e-12,
Organism=Homo sapiens, GI310128097, Length=184, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=5e-11,
Organism=Escherichia coli, GI1787250, Length=1250, Percent_Identity=58.24, Blast_Score=1383, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=444, Percent_Identity=31.981981981982, Blast_Score=176, Evalue=9e-45,
Organism=Escherichia coli, GI1788042, Length=451, Percent_Identity=31.2638580931264, Blast_Score=167, Evalue=5e-42,
Organism=Escherichia coli, GI87081896, Length=474, Percent_Identity=28.2700421940928, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI1787715, Length=453, Percent_Identity=29.3598233995585, Blast_Score=150, Evalue=5e-37,
Organism=Escherichia coli, GI1787684, Length=455, Percent_Identity=27.4725274725275, Blast_Score=143, Evalue=7e-35,
Organism=Escherichia coli, GI1787558, Length=428, Percent_Identity=29.2056074766355, Blast_Score=136, Evalue=9e-33,
Organism=Escherichia coli, GI1786504, Length=471, Percent_Identity=27.1762208067941, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87082295, Length=432, Percent_Identity=28.2407407407407, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI87081926, Length=425, Percent_Identity=24.9411764705882, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1787653, Length=260, Percent_Identity=23.4615384615385, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25144435, Length=461, Percent_Identity=31.4533622559653, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17534447, Length=480, Percent_Identity=30.4166666666667, Blast_Score=166, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=458, Percent_Identity=31.2227074235808, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=31.5533980582524, Blast_Score=153, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI115532534, Length=394, Percent_Identity=31.4720812182741, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534119, Length=481, Percent_Identity=28.8981288981289, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=480, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=437, Percent_Identity=27.6887871853547, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71986308, Length=425, Percent_Identity=26.3529411764706, Blast_Score=136, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25143874, Length=430, Percent_Identity=27.6744186046512, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143876, Length=430, Percent_Identity=27.6744186046512, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=433, Percent_Identity=26.5588914549654, Blast_Score=122, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=420, Percent_Identity=27.8571428571429, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71995606, Length=439, Percent_Identity=25.7403189066059, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71995613, Length=396, Percent_Identity=24.7474747474747, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71990744, Length=303, Percent_Identity=29.042904290429, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=435, Percent_Identity=24.5977011494253, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146391, Length=339, Percent_Identity=22.7138643067847, Blast_Score=76, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25146394, Length=339, Percent_Identity=22.7138643067847, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566756, Length=339, Percent_Identity=22.7138643067847, Blast_Score=76, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=452, Percent_Identity=31.6371681415929, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=477, Percent_Identity=31.2368972746331, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=449, Percent_Identity=30.2895322939866, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=464, Percent_Identity=31.6810344827586, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=469, Percent_Identity=28.3582089552239, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=507, Percent_Identity=28.4023668639053, Blast_Score=144, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6323822, Length=505, Percent_Identity=27.3267326732673, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=504, Percent_Identity=25.3968253968254, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=24.8466257668712, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362580, Length=450, Percent_Identity=31.3333333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472918, Length=450, Percent_Identity=31.3333333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472926, Length=450, Percent_Identity=31.3333333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI62472936, Length=450, Percent_Identity=31.3333333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21356737, Length=450, Percent_Identity=31.3333333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24650465, Length=457, Percent_Identity=29.3216630196937, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24668425, Length=525, Percent_Identity=29.5238095238095, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668417, Length=525, Percent_Identity=29.5238095238095, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668413, Length=525, Percent_Identity=29.5238095238095, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129399, Length=444, Percent_Identity=29.2792792792793, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24585660, Length=456, Percent_Identity=26.7543859649123, Blast_Score=146, Evalue=8e-35,
Organism=Drosophila melanogaster, GI28574525, Length=439, Percent_Identity=26.6514806378132, Blast_Score=134, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28571806, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571802, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571800, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571798, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571796, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571794, Length=451, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24666674, Length=429, Percent_Identity=28.2051282051282, Blast_Score=123, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24638878, Length=418, Percent_Identity=25.1196172248804, Blast_Score=104, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24638876, Length=418, Percent_Identity=25.1196172248804, Blast_Score=104, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281360299, Length=350, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360297, Length=350, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360295, Length=350, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24586250, Length=350, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360301, Length=350, Percent_Identity=25.7142857142857, Blast_Score=85, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45552499, Length=345, Percent_Identity=25.5072463768116, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360303, Length=350, Percent_Identity=25.1428571428571, Blast_Score=83, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 132146; Mature: 132015

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNISVSKVAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIR
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
STARKLIEALRAKHKGTGIEGLVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKI
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
SNGDWKSHIGGGRSLFVNAATWGLVVTGKLTNTVNDRGLSAALTRLIARCGEPVIRRGVD
CCCCCHHHCCCCCEEEEEEEEEEEEEEECHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
MAMRMMGEQFVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGRASAGRGIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNI
HHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
DAEEADRLELSLDLLQSLCEDPDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VRLVKGAYWDAEIKRAQVDGLEDFPVYTRKVHTDVSYIACARKLLAATDVIFPQFATHNA
HHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHCCCH
QTLATIYHLAGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAY
HHHHHHHHHCCCCCCCCCEEEEEHHCCCCCHHHHCCCHHHCCCCEEEEECCCCHHHHHHH
LVRRLLENGANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARR
HHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
NSAGFDLSNEVTLAELSKTLKETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVT
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHH
EIAEADVAKAMKAAQTATTSWSAVAPAERAACLERAADIMQRDMPALLGLVMREAGKSMP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NAIAEVREAIDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCC
VLAKPAEETPLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEV
CCCCCCCCCCCCHHCCCEEEECCCCCHHHHHHCCCCCCCCEEEEECCCCCCEEEECCHHH
ARLIQAQLASRLLPNGKPVPLIAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVLCLQEDVADRILTMLKGALRELSIGRTDQLKVDIGPVITDEAKNTIEKHIQAMRDLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
RKVEQLPLGPETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDEMESLIDDINST
HHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYGLTFGLHTRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPL
CCEEEEEHHHHHHHHHHHHHHHEEECEEEECCCCEEHEEECCCCCCCCCCCCCCCCCCCH
YLGRLVETAPIPPRHASVHTDAALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCC
PVGERNLYALHPRGRVLLVPQTEIGLYRQLTAVLATGNTAVIDEACGLRAVLKDLPETVA
CCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHH
ARAIWTGDWQADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYC
HHEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCHHH
LNWLLEEVSTSINTTAAGGNASLMAIG
HHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TDNISVSKVAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIR
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
STARKLIEALRAKHKGTGIEGLVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKI
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
SNGDWKSHIGGGRSLFVNAATWGLVVTGKLTNTVNDRGLSAALTRLIARCGEPVIRRGVD
CCCCCHHHCCCCCEEEEEEEEEEEEEEECHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
MAMRMMGEQFVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGRASAGRGIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNI
HHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
DAEEADRLELSLDLLQSLCEDPDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VRLVKGAYWDAEIKRAQVDGLEDFPVYTRKVHTDVSYIACARKLLAATDVIFPQFATHNA
HHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHCCCH
QTLATIYHLAGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAY
HHHHHHHHHCCCCCCCCCEEEEEHHCCCCCHHHHCCCHHHCCCCEEEEECCCCHHHHHHH
LVRRLLENGANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARR
HHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
NSAGFDLSNEVTLAELSKTLKETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVT
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHH
EIAEADVAKAMKAAQTATTSWSAVAPAERAACLERAADIMQRDMPALLGLVMREAGKSMP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NAIAEVREAIDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCC
VLAKPAEETPLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEV
CCCCCCCCCCCCHHCCCEEEECCCCCHHHHHHCCCCCCCCEEEEECCCCCCEEEECCHHH
ARLIQAQLASRLLPNGKPVPLIAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVLCLQEDVADRILTMLKGALRELSIGRTDQLKVDIGPVITDEAKNTIEKHIQAMRDLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
RKVEQLPLGPETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDEMESLIDDINST
HHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYGLTFGLHTRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPL
CCEEEEEHHHHHHHHHHHHHHHEEECEEEECCCCEEHEEECCCCCCCCCCCCCCCCCCCH
YLGRLVETAPIPPRHASVHTDAALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEECCC
PVGERNLYALHPRGRVLLVPQTEIGLYRQLTAVLATGNTAVIDEACGLRAVLKDLPETVA
CCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHH
ARAIWTGDWQADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYC
HHEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCHHH
LNWLLEEVSTSINTTAAGGNASLMAIG
HHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004223; 10715000 [H]