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The map label for this gene is idhA [H]

Identifier: 225686484

GI number: 225686484

Start: 669521

End: 670525

Strand: Reverse

Name: idhA [H]

Synonym: BMEA_B0686

Alternate gene names: 225686484

Gene position: 670525-669521 (Counterclockwise)

Preceding gene: 225686490

Following gene: 225686483

Centisome position: 56.56

GC content: 59.1

Gene sequence:

>1005_bases
ATGGTAACACGACTGGCACTGCTCGGCGCAGGCCGTATCGGCAAGGTTCATGCGGGCGCAATCGCTTCGGACAGACGCGC
CAGGCTGCTGGCGGTTGCCGATGCAAATGAGGACGCTGCGGAAGCTATTGCGGATGCTTCCGGCGCACAAGTCCGCAGCA
TTGACGAGATTGAGCGGGCAAGCGATGTGGATGCCGTGCTGATCTGCACGCCGACCAACACCCATGCCGACCTGATCGAG
CGTTTTGCCCGTGCGGGCAAGGCTGTGTTCTGTGAAAAGCCCATCGATCTCGATATTGCGCGTGTGCACGCCTGCCTTGC
CGTCATCAGGGAAACGGGCGCGAAGGTGATGCTCGGTTTCAACCGGCGTTTTGACCCGCATTTCGTTGCCGTGCGCAAGG
CCATTGATGACGGGCGCATCGGCAAGGTGGAAATGGTGACGATCACCAGCCGCGATCCGGGCGCGCCGCCTGCGGACTAT
ATCAAGGTTTCAGGCGGCATCTTCCGCGATATGACCATCCATGATTTCGACATGGCGCGTTTTCTTCTGGGTGAGGAGAT
TGAAAGCGTTGCGGCTTCCGCTTCGGTGCTTGTCGATCCGAAGATTGGCGAGCTTGGCGATTATGACAGTGCAAGCGTTA
TCCTGACCACAGCTTCGGGACGCCAATGCGTGATTTCCAATTCGCGCCGCGCTTCCTATGGTTATGACCAGCGCATTGAG
GTGCATGGTTCGCTCGGCGCTGTTTCGGCTGAAAACCAGCGGCCCGTTTCCATAGAGATCGCTTCAAAGGATGGTTATAA
CCGCCCGCCGCTGCATGATTTTTTCATGACGCGCTATACGGCGGCCTATGCGGCGGAAATCGGCGCTTTCATCGATGCGC
TGGACAGCGGCAAAGCGCCGATGCCTTCGGCTGAAGACGGCTTGAAGGCGCTGGCTCTGGCGGAAGCGGCATTGCGCTCC
GTCAAGGAAGGCCGAACCGTCAAGGTCGCGGAAATTCTGCCCTGA

Upstream 100 bases:

>100_bases
TGCATCGTATTCCATCCCCAATAAGCGGGAAACGGGCGAAAGGGAATATGGATGAATTTATCGGTCAATCGAGGATGACC
GCTTCCGGGAGGATAAGGCA

Downstream 100 bases:

>100_bases
CCGTTCGGTTTCATTGCCTTGTATATGCAGGCTCGTCCCCATGCCTTTGCAAACATCACCACTTGCAAAGCGGGGGATTC
AACTGCGATATGCGGATATG

Product: Rhizopine catabolism protein mocA

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVTRLALLGAGRIGKVHAGAIASDRRARLLAVADANEDAAEAIADASGAQVRSIDEIERASDVDAVLICTPTNTHADLIE
RFARAGKAVFCEKPIDLDIARVHACLAVIRETGAKVMLGFNRRFDPHFVAVRKAIDDGRIGKVEMVTITSRDPGAPPADY
IKVSGGIFRDMTIHDFDMARFLLGEEIESVAASASVLVDPKIGELGDYDSASVILTTASGRQCVISNSRRASYGYDQRIE
VHGSLGAVSAENQRPVSIEIASKDGYNRPPLHDFFMTRYTAAYAAEIGAFIDALDSGKAPMPSAEDGLKALALAEAALRS
VKEGRTVKVAEILP

Sequences:

>Translated_334_residues
MVTRLALLGAGRIGKVHAGAIASDRRARLLAVADANEDAAEAIADASGAQVRSIDEIERASDVDAVLICTPTNTHADLIE
RFARAGKAVFCEKPIDLDIARVHACLAVIRETGAKVMLGFNRRFDPHFVAVRKAIDDGRIGKVEMVTITSRDPGAPPADY
IKVSGGIFRDMTIHDFDMARFLLGEEIESVAASASVLVDPKIGELGDYDSASVILTTASGRQCVISNSRRASYGYDQRIE
VHGSLGAVSAENQRPVSIEIASKDGYNRPPLHDFFMTRYTAAYAAEIGAFIDALDSGKAPMPSAEDGLKALALAEAALRS
VKEGRTVKVAEILP
>Mature_334_residues
MVTRLALLGAGRIGKVHAGAIASDRRARLLAVADANEDAAEAIADASGAQVRSIDEIERASDVDAVLICTPTNTHADLIE
RFARAGKAVFCEKPIDLDIARVHACLAVIRETGAKVMLGFNRRFDPHFVAVRKAIDDGRIGKVEMVTITSRDPGAPPADY
IKVSGGIFRDMTIHDFDMARFLLGEEIESVAASASVLVDPKIGELGDYDSASVILTTASGRQCVISNSRRASYGYDQRIE
VHGSLGAVSAENQRPVSIEIASKDGYNRPPLHDFFMTRYTAAYAAEIGAFIDALDSGKAPMPSAEDGLKALALAEAALRS
VKEGRTVKVAEILP

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789848, Length=139, Percent_Identity=29.4964028776978, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581117, Length=242, Percent_Identity=25.2066115702479, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 35649; Mature: 35649

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRLALLGAGRIGKVHAGAIASDRRARLLAVADANEDAAEAIADASGAQVRSIDEIERA
CCEEEEEECCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHH
SDVDAVLICTPTNTHADLIERFARAGKAVFCEKPIDLDIARVHACLAVIRETGAKVMLGF
CCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEC
NRRFDPHFVAVRKAIDDGRIGKVEMVTITSRDPGAPPADYIKVSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHEEEECCCEEECCEECHHHHHH
FLLGEEIESVAASASVLVDPKIGELGDYDSASVILTTASGRQCVISNSRRASYGYDQRIE
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEEE
VHGSLGAVSAENQRPVSIEIASKDGYNRPPLHDFFMTRYTAAYAAEIGAFIDALDSGKAP
EECCCCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MPSAEDGLKALALAEAALRSVKEGRTVKVAEILP
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MVTRLALLGAGRIGKVHAGAIASDRRARLLAVADANEDAAEAIADASGAQVRSIDEIERA
CCEEEEEECCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHH
SDVDAVLICTPTNTHADLIERFARAGKAVFCEKPIDLDIARVHACLAVIRETGAKVMLGF
CCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEC
NRRFDPHFVAVRKAIDDGRIGKVEMVTITSRDPGAPPADYIKVSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHEEEECCCEEECCEECHHHHHH
FLLGEEIESVAASASVLVDPKIGELGDYDSASVILTTASGRQCVISNSRRASYGYDQRIE
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEEE
VHGSLGAVSAENQRPVSIEIASKDGYNRPPLHDFFMTRYTAAYAAEIGAFIDALDSGKAP
EECCCCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MPSAEDGLKALALAEAALRSVKEGRTVKVAEILP
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]