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The map label for this gene is pcaB [H]

Identifier: 225686426

GI number: 225686426

Start: 606565

End: 607629

Strand: Direct

Name: pcaB [H]

Synonym: BMEA_B0620

Alternate gene names: 225686426

Gene position: 606565-607629 (Clockwise)

Preceding gene: 225686425

Following gene: 225686427

Centisome position: 51.16

GC content: 59.72

Gene sequence:

>1065_bases
ATGAGCATATCGGTTTTCGAGCACCCGTTCCTGACCGGCCTTTTTGGCGATGACGAGGAAATCAGCAGCCTTTTCACCGC
CTATGCCGACATCGCCGCCATGCTGAAATTCGAGGCGGCGCTTGCGGGCGCGCAGGCCGATCTGGGCATTATCCCAGCCC
ATGCGGCTGAAAGGATCATGAGTGCCACGGAAACGATGGAGCCTGATCTGGCGCAACTGGAGCACGGCACGGCACGCGAT
GGCGTGGTGGTTCCCGCCCTTGTGCGCAATCTGCGAAAAACTGTCGGTGAAGACGTCGCCGCCCATGTCCATTTCGGCGC
GACCAGTCAGGATGTGATCGACACCAGCCTCATGCTGCGGCTTGCCCGCGTGCGCGATATTCTTGTAGCCCGCATCGAAC
AGCTTTCGGAGCGGTTCAACTGGCTGGAAACCACTTTCGGCCAGAATGATTTGACCGCCTATACGCGGATGCAGCCGGCT
ATTTCCACAACCGTTGCGGACCGGGTTGAAAGCTGGCGCGCACCTTTCAGTGATTATGCGCAGCGCCTTGCCGCGCTGCA
ATTTCCGCTCCAGTTTGGCGGAGCAGCCGGAACACTTGAAAAATTCGTAGGTAAGGGCGCAAAATTGCGGGCGGAGCTGG
CAAAGCGCCTCGGCCTCGAAGACCGGCCCCAATGGCACAGCCAGCGCGCTTTTATTGCCGATTTTGGCCATCTCCTTTCG
CTTGTGACCGGCTCGCTCGGCAAGTTCGGGCAGGATATCGCCCTGATGGCGGAACTGCGCGACGAGATTTCGCTTTCAGG
CGGCAGCGGGTCGTCGGCCATGCCGCACAAGCAGAACCCCGTAAGGGCCGAGCTTCTGGTGACCCTTGCACGGTTCAATG
CCGTGCAGGTTTCAGGGCTGCATCAGGCCATGGTGCACGAACAGGAGCGTTCAGGCACCGCCTGGATGCTGGAATGGATG
ATTTTGCCGCCAGTTGTCGCCGCCACCGGCGCAGCACTGAAAGCGGCATTGGTGTTGAGCGACAATATCGTTCGCATGGG
CAAGGATCGACTGCCGGAAACATAA

Upstream 100 bases:

>100_bases
GCGCGTGCCAACCTTGATCGGCCAGCGCGAGGGCGACGTCTATCACTTCGATATCCACCTTCAGGGCGAAAAAGAAACGG
TCTTTTTCGATATTTAAAAG

Downstream 100 bases:

>100_bases
CTGTTCGGATATCGGTTATAAGGATTTTTTCATTTTACATGACCAGTTAGATAGGCATTCTGAAAATAAGCTCAATCATT
CCAAACTGCGCGGAGACGGC

Product: 3-carboxy-cis,cis-muconate cycloisomerase

Products: NA

Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSISVFEHPFLTGLFGDDEEISSLFTAYADIAAMLKFEAALAGAQADLGIIPAHAAERIMSATETMEPDLAQLEHGTARD
GVVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLRLARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPA
ISTTVADRVESWRAPFSDYAQRLAALQFPLQFGGAAGTLEKFVGKGAKLRAELAKRLGLEDRPQWHSQRAFIADFGHLLS
LVTGSLGKFGQDIALMAELRDEISLSGGSGSSAMPHKQNPVRAELLVTLARFNAVQVSGLHQAMVHEQERSGTAWMLEWM
ILPPVVAATGAALKAALVLSDNIVRMGKDRLPET

Sequences:

>Translated_354_residues
MSISVFEHPFLTGLFGDDEEISSLFTAYADIAAMLKFEAALAGAQADLGIIPAHAAERIMSATETMEPDLAQLEHGTARD
GVVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLRLARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPA
ISTTVADRVESWRAPFSDYAQRLAALQFPLQFGGAAGTLEKFVGKGAKLRAELAKRLGLEDRPQWHSQRAFIADFGHLLS
LVTGSLGKFGQDIALMAELRDEISLSGGSGSSAMPHKQNPVRAELLVTLARFNAVQVSGLHQAMVHEQERSGTAWMLEWM
ILPPVVAATGAALKAALVLSDNIVRMGKDRLPET
>Mature_353_residues
SISVFEHPFLTGLFGDDEEISSLFTAYADIAAMLKFEAALAGAQADLGIIPAHAAERIMSATETMEPDLAQLEHGTARDG
VVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLRLARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPAI
STTVADRVESWRAPFSDYAQRLAALQFPLQFGGAAGTLEKFVGKGAKLRAELAKRLGLEDRPQWHSQRAFIADFGHLLSL
VTGSLGKFGQDIALMAELRDEISLSGGSGSSAMPHKQNPVRAELLVTLARFNAVQVSGLHQAMVHEQERSGTAWMLEWMI
LPPVVAATGAALKAALVLSDNIVRMGKDRLPET

Specific function: Catalyzes an anti cycloisomerization [H]

COG id: COG0015

COG function: function code F; Adenylosuccinate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019468
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761
- InterPro:   IPR012789 [H]

Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]

EC number: =5.5.1.2 [H]

Molecular weight: Translated: 38501; Mature: 38369

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVFEHPFLTGLFGDDEEISSLFTAYADIAAMLKFEAALAGAQADLGIIPAHAAERIM
CCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
SATETMEPDLAQLEHGTARDGVVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLR
HHHHHCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
LARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPAISTTVADRVESWRAPFSDYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCHHHHH
QRLAALQFPLQFGGAAGTLEKFVGKGAKLRAELAKRLGLEDRPQWHSQRAFIADFGHLLS
HHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LVTGSLGKFGQDIALMAELRDEISLSGGSGSSAMPHKQNPVRAELLVTLARFNAVQVSGL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHH
HQAMVHEQERSGTAWMLEWMILPPVVAATGAALKAALVLSDNIVRMGKDRLPET
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SISVFEHPFLTGLFGDDEEISSLFTAYADIAAMLKFEAALAGAQADLGIIPAHAAERIM
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
SATETMEPDLAQLEHGTARDGVVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLR
HHHHHCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
LARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPAISTTVADRVESWRAPFSDYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCHHHHH
QRLAALQFPLQFGGAAGTLEKFVGKGAKLRAELAKRLGLEDRPQWHSQRAFIADFGHLLS
HHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LVTGSLGKFGQDIALMAELRDEISLSGGSGSSAMPHKQNPVRAELLVTLARFNAVQVSGL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHH
HQAMVHEQERSGTAWMLEWMILPPVVAATGAALKAALVLSDNIVRMGKDRLPET
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]