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The map label for this gene is dnaQ [H]

Identifier: 225686408

GI number: 225686408

Start: 587997

End: 588671

Strand: Direct

Name: dnaQ [H]

Synonym: BMEA_B0599

Alternate gene names: 225686408

Gene position: 587997-588671 (Clockwise)

Preceding gene: 225686407

Following gene: 225686409

Centisome position: 49.6

GC content: 53.93

Gene sequence:

>675_bases
ATGACAGACATTTACAACCCATCAATCCATACGCGCAAAAAACGCGTCATTGTCTTTGATACCGAAACGACAGGAATTTT
GCCTTACGACAGGATCATTACGCTTGGCGCCGTGAAGATCGAAGGCGGCGAATTACTGACGCAATCACTTTATCTGATTT
TCGATCCGCGCAAGGATAGCTCGCCGCAAGCTGAGGCTGTCCACGGTTTCGACAACTGGATGACACGCTATCAGGATCTC
TTCCACGAGCTTGCCGCGCCAATCAGAAAATGGTTTTCATGGGCCGACGAAGTGGTCGCCCATAATGCCCAATTCGACAT
GCATTATATCCAGCGTGAGTTTCGCAAGGCAGAGGTCGATATGCTCGACCAGCCGGTTTACTGCACCATGGACGGCGCCA
GACGGCTTTGGAGAGGCGATTCTACCAAACTTGACCATTGCCTCGCAAAGATTGGCCTTGCGCGCACGGGGCACCGACAC
GGCGCGCTGGAAGACGCCTACCTGACCGCAGGCCTCTATCTCCATCAGCAAGGCGTTGCAAAACCGCTGCCGAAAATCAA
TTCCTGGCAACCGCCCAAAAACCTGAAACCCTATCCTGAGCGGCCTGCGGGCGAGCTTCCCCGCCGAACACCAAAACGCA
GGAGTGCTGCAGTTTCCGCTTGTTCAACAGTTTAG

Upstream 100 bases:

>100_bases
AGCCTGACGTCCTTGCCTTTGCCCTCTTGTGGTCTTGGCGACGCTTTTTCATTTCGCTTGTAAAATAATGGTTTTGTGCC
TCGCAGGCACGGGGCAGAGC

Downstream 100 bases:

>100_bases
GCTGTAGTGACGAAATAAATTACGGTTCGGCGGGAAGGTATTTTCTGCCGACAGAAGAAATAACTTTAGAAAGTTGATAT
ATAGGATTGTTTTGATTGAG

Product: exonuclease, DNA polymerase III, epsilon subunit family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTDIYNPSIHTRKKRVIVFDTETTGILPYDRIITLGAVKIEGGELLTQSLYLIFDPRKDSSPQAEAVHGFDNWMTRYQDL
FHELAAPIRKWFSWADEVVAHNAQFDMHYIQREFRKAEVDMLDQPVYCTMDGARRLWRGDSTKLDHCLAKIGLARTGHRH
GALEDAYLTAGLYLHQQGVAKPLPKINSWQPPKNLKPYPERPAGELPRRTPKRRSAAVSACSTV

Sequences:

>Translated_224_residues
MTDIYNPSIHTRKKRVIVFDTETTGILPYDRIITLGAVKIEGGELLTQSLYLIFDPRKDSSPQAEAVHGFDNWMTRYQDL
FHELAAPIRKWFSWADEVVAHNAQFDMHYIQREFRKAEVDMLDQPVYCTMDGARRLWRGDSTKLDHCLAKIGLARTGHRH
GALEDAYLTAGLYLHQQGVAKPLPKINSWQPPKNLKPYPERPAGELPRRTPKRRSAAVSACSTV
>Mature_223_residues
TDIYNPSIHTRKKRVIVFDTETTGILPYDRIITLGAVKIEGGELLTQSLYLIFDPRKDSSPQAEAVHGFDNWMTRYQDLF
HELAAPIRKWFSWADEVVAHNAQFDMHYIQREFRKAEVDMLDQPVYCTMDGARRLWRGDSTKLDHCLAKIGLARTGHRHG
ALEDAYLTAGLYLHQQGVAKPLPKINSWQPPKNLKPYPERPAGELPRRTPKRRSAAVSACSTV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=181, Percent_Identity=29.2817679558011, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25614; Mature: 25482

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIYNPSIHTRKKRVIVFDTETTGILPYDRIITLGAVKIEGGELLTQSLYLIFDPRKDS
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHEEEEEEEEECCCHHHHCCEEEEECCCCCC
SPQAEAVHGFDNWMTRYQDLFHELAAPIRKWFSWADEVVAHNAQFDMHYIQREFRKAEVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLDQPVYCTMDGARRLWRGDSTKLDHCLAKIGLARTGHRHGALEDAYLTAGLYLHQQGVA
HCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
KPLPKINSWQPPKNLKPYPERPAGELPRRTPKRRSAAVSACSTV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TDIYNPSIHTRKKRVIVFDTETTGILPYDRIITLGAVKIEGGELLTQSLYLIFDPRKDS
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHEEEEEEEEECCCHHHHCCEEEEECCCCCC
SPQAEAVHGFDNWMTRYQDLFHELAAPIRKWFSWADEVVAHNAQFDMHYIQREFRKAEVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLDQPVYCTMDGARRLWRGDSTKLDHCLAKIGLARTGHRHGALEDAYLTAGLYLHQQGVA
HCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
KPLPKINSWQPPKNLKPYPERPAGELPRRTPKRRSAAVSACSTV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]