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The map label for this gene is recG [H]

Identifier: 225686367

GI number: 225686367

Start: 541793

End: 543913

Strand: Direct

Name: recG [H]

Synonym: BMEA_B0555

Alternate gene names: 225686367

Gene position: 541793-543913 (Clockwise)

Preceding gene: 225686363

Following gene: 225686371

Centisome position: 45.7

GC content: 60.16

Gene sequence:

>2121_bases
ATGTTCGACCCCATGCGCCCATCCATGCTCGATCCATTTTTTGCGTCCGTCCGTTCACTTTCAGGCATCGGCCCGAAAGT
GGCCGTCCTGCTTGGAAAATTGCTGGGAACCGATGTGCCGGGCGGCGAACCGAAAATAGGCCAGCTTCTTTTCCTTCCGC
CCCACAGCATCATTGACCGGCGCAACCGGCCCGGTATCGCTTTTGCGCAGGAGGGGGCCATTGTCACGCTGGAAGTGACC
GTCGATCAGCACCAGCCCGCACCGAAAGGGCGTGGCAATGTTCCCCACCGTGTTTTTGCACATGACGATACGGGGGAAAT
CGCGCTGACCTTCTTCCACGCCCAATTGCCCTGGCTGCAAAAGATGCTGCCGGAAGGCGAAACCGTTATTGTTTCAGGCA
AGGTGGAATGGTTCAACGGGCGCGCTTCCATGGTGCACCCGGATTATATTGCAAGCATGGACGATGCCGCCAGCCTGCCG
CTTGTCGAGCCGGTCTATCCGCTGACGGCCGGCCTCTCACCCAAGACACTTGGCCGCGCCATCAAGGAGGCGCTGACCCG
CGTGCCTGTCCTGCCGGAATGGATCGATGCGCCTTTGCTGGCGCGCGAAGGTTTCCCAGCGTTTCAGCAGGCGCTCAACA
CGCTGCATCAACCGGAAGACCCCGGCGATATCGCGCTTGAAAGCATTACGCGGCGCAGGCTTGCCTATGATGAATTTCTG
GCGGGCCAACTGGCGCTTGCCCTTGTGCGCGCCAAGACTCGCAGGCTTTCAGGCCGCCCGCTTGAAGGCACCGGCAACAT
CGTGGCCGAAATCATGCGCCACCTGCCCTATCGCCTGACCAAAGCCCAGGAACAGGCCGTGCGTGAGATCATCACCGACC
TCAAATCGCCCCAGCGCATGTTGCGGCTTTTGCAGGGCGATGTCGGTTCCGGCAAAACCGTGGTGGGCCTGCTTTCCATG
GCCCATGCGGCTGAATCCGGCGGGCAATCGGCACTCATGGCCCCAACGGAAGTGCTGGCACGCCAGCATTTTGCAACTAT
CGCGCCGCTCGCGGAAAAAGCCGGGTTGAAAGCGGCCCTTCTTACAGGCCGCGAAAAGGGGCGCGAACGAAATGCCGTTC
TGGAAGGGTTGAAAAGCGGCGAAATCGATATTGTCATCGGCACGCATGCGCTGTTTCAGGAAAAGGTCGAATATCACGAT
CTGGTTTTTGTCATCATCGACGAACAGCACCGTTTCGGCGTCCATCAGCGCCTCATGCTGACCGCCAAAGGCTCCGCGCC
CGACATGCTGGTGATGACCGCAACGCCGATCCCGCGCACGCTTGTTCTCACCGCCTTCGGCGATATGGACGTGTCCAAGC
TCACGGAAAAGCCTGTCGGACGCCAGCCCATCACCACCGCAATCGTGCCGATGGAACGCATGGGCGAACTGGTGGAGCGC
ATCAGAAAGGCGGTCAGTGAAGACCAGAAGATTTACTGGATTTGCCCTCTGGTCGAGGAATCTGAAGTCGTTGAACTGAC
ATCAGCCGAGGAGCGTTTCGAGAGCCTCAAATCCGTTTTCGGCGAGCGGATCGGCCTTATTCATGGCCGCATGAGCGGCG
CGGAAAAAGACGAAGCCATGCGCGCCTTCAAACAGGGCGAGACGCGGCTTCTGGTGGCGACAACCGTGATCGAGGTTGGT
GTGGACGTGCCCGATGCCACCATCATCGTCATCGAACATGCGGAACGTTTCGGCCTGTCGCAATTGCACCAGTTGCGCGG
GCGCGTGGGGCGCGGCGACAAGCCCTCAACCTGTCTTCTGCTCTATAAGGGGCCGCTTGGTGAGATTGCGCAGGCGCGGC
TGAAAGTGATGCGCGAAACAGAAGACGGTTTCCGCATTGCAGAAGAAGACCTGAAATTGCGCGGCGAAGGCGAATTGCTG
GGCACGCGCCAGTCCGGCACGCCGGGTTTCCGCCTTGCCTCCATCGAGGCGCATGGTGACCTTCTGGAGATCGCCCGCAA
GGATGCGCGCTATATTCTGGCGAGCGATCCCGATCTGGAATCCGAACGCGGGCAGGCTTTGCGTGTGCTGCTCTATCTCT
TCGGGCGCGACGAGGCCATCCGCCTGCTTAGGGCAGGATAG

Upstream 100 bases:

>100_bases
ATAGCATCTGGGGCGCAAACGGGAACCCGTTTATCGGATAAGAACAAAAAGAGCACAGAAAGATTGCGCACCGCCCTTGC
GCCGCGAGGCGAAGCAGTTA

Downstream 100 bases:

>100_bases
CACTCTCTTTGCTCCCCCTCATCCTGAGATGCGGAGCAAAGCGAAGCCTCGAATTGCGATAAGTCTATTGAGAACCAATG
CCTTACCCGTCGAGACGGTG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MFDPMRPSMLDPFFASVRSLSGIGPKVAVLLGKLLGTDVPGGEPKIGQLLFLPPHSIIDRRNRPGIAFAQEGAIVTLEVT
VDQHQPAPKGRGNVPHRVFAHDDTGEIALTFFHAQLPWLQKMLPEGETVIVSGKVEWFNGRASMVHPDYIASMDDAASLP
LVEPVYPLTAGLSPKTLGRAIKEALTRVPVLPEWIDAPLLAREGFPAFQQALNTLHQPEDPGDIALESITRRRLAYDEFL
AGQLALALVRAKTRRLSGRPLEGTGNIVAEIMRHLPYRLTKAQEQAVREIITDLKSPQRMLRLLQGDVGSGKTVVGLLSM
AHAAESGGQSALMAPTEVLARQHFATIAPLAEKAGLKAALLTGREKGRERNAVLEGLKSGEIDIVIGTHALFQEKVEYHD
LVFVIIDEQHRFGVHQRLMLTAKGSAPDMLVMTATPIPRTLVLTAFGDMDVSKLTEKPVGRQPITTAIVPMERMGELVER
IRKAVSEDQKIYWICPLVEESEVVELTSAEERFESLKSVFGERIGLIHGRMSGAEKDEAMRAFKQGETRLLVATTVIEVG
VDVPDATIIVIEHAERFGLSQLHQLRGRVGRGDKPSTCLLLYKGPLGEIAQARLKVMRETEDGFRIAEEDLKLRGEGELL
GTRQSGTPGFRLASIEAHGDLLEIARKDARYILASDPDLESERGQALRVLLYLFGRDEAIRLLRAG

Sequences:

>Translated_706_residues
MFDPMRPSMLDPFFASVRSLSGIGPKVAVLLGKLLGTDVPGGEPKIGQLLFLPPHSIIDRRNRPGIAFAQEGAIVTLEVT
VDQHQPAPKGRGNVPHRVFAHDDTGEIALTFFHAQLPWLQKMLPEGETVIVSGKVEWFNGRASMVHPDYIASMDDAASLP
LVEPVYPLTAGLSPKTLGRAIKEALTRVPVLPEWIDAPLLAREGFPAFQQALNTLHQPEDPGDIALESITRRRLAYDEFL
AGQLALALVRAKTRRLSGRPLEGTGNIVAEIMRHLPYRLTKAQEQAVREIITDLKSPQRMLRLLQGDVGSGKTVVGLLSM
AHAAESGGQSALMAPTEVLARQHFATIAPLAEKAGLKAALLTGREKGRERNAVLEGLKSGEIDIVIGTHALFQEKVEYHD
LVFVIIDEQHRFGVHQRLMLTAKGSAPDMLVMTATPIPRTLVLTAFGDMDVSKLTEKPVGRQPITTAIVPMERMGELVER
IRKAVSEDQKIYWICPLVEESEVVELTSAEERFESLKSVFGERIGLIHGRMSGAEKDEAMRAFKQGETRLLVATTVIEVG
VDVPDATIIVIEHAERFGLSQLHQLRGRVGRGDKPSTCLLLYKGPLGEIAQARLKVMRETEDGFRIAEEDLKLRGEGELL
GTRQSGTPGFRLASIEAHGDLLEIARKDARYILASDPDLESERGQALRVLLYLFGRDEAIRLLRAG
>Mature_706_residues
MFDPMRPSMLDPFFASVRSLSGIGPKVAVLLGKLLGTDVPGGEPKIGQLLFLPPHSIIDRRNRPGIAFAQEGAIVTLEVT
VDQHQPAPKGRGNVPHRVFAHDDTGEIALTFFHAQLPWLQKMLPEGETVIVSGKVEWFNGRASMVHPDYIASMDDAASLP
LVEPVYPLTAGLSPKTLGRAIKEALTRVPVLPEWIDAPLLAREGFPAFQQALNTLHQPEDPGDIALESITRRRLAYDEFL
AGQLALALVRAKTRRLSGRPLEGTGNIVAEIMRHLPYRLTKAQEQAVREIITDLKSPQRMLRLLQGDVGSGKTVVGLLSM
AHAAESGGQSALMAPTEVLARQHFATIAPLAEKAGLKAALLTGREKGRERNAVLEGLKSGEIDIVIGTHALFQEKVEYHD
LVFVIIDEQHRFGVHQRLMLTAKGSAPDMLVMTATPIPRTLVLTAFGDMDVSKLTEKPVGRQPITTAIVPMERMGELVER
IRKAVSEDQKIYWICPLVEESEVVELTSAEERFESLKSVFGERIGLIHGRMSGAEKDEAMRAFKQGETRLLVATTVIEVG
VDVPDATIIVIEHAERFGLSQLHQLRGRVGRGDKPSTCLLLYKGPLGEIAQARLKVMRETEDGFRIAEEDLKLRGEGELL
GTRQSGTPGFRLASIEAHGDLLEIARKDARYILASDPDLESERGQALRVLLYLFGRDEAIRLLRAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=685, Percent_Identity=40.2919708029197, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787357, Length=386, Percent_Identity=36.7875647668394, Blast_Score=232, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77546; Mature: 77546

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDPMRPSMLDPFFASVRSLSGIGPKVAVLLGKLLGTDVPGGEPKIGQLLFLPPHSIIDR
CCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHCC
RNRPGIAFAQEGAIVTLEVTVDQHQPAPKGRGNVPHRVFAHDDTGEIALTFFHAQLPWLQ
CCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCHHHH
KMLPEGETVIVSGKVEWFNGRASMVHPDYIASMDDAASLPLVEPVYPLTAGLSPKTLGRA
HHCCCCCEEEEEEEEEEECCCCCEECCHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
IKEALTRVPVLPEWIDAPLLAREGFPAFQQALNTLHQPEDPGDIALESITRRRLAYDEFL
HHHHHHHCCCCHHHHCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AGQLALALVRAKTRRLSGRPLEGTGNIVAEIMRHLPYRLTKAQEQAVREIITDLKSPQRM
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHH
LRLLQGDVGSGKTVVGLLSMAHAAESGGQSALMAPTEVLARQHFATIAPLAEKAGLKAAL
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEE
LTGREKGRERNAVLEGLKSGEIDIVIGTHALFQEKVEYHDLVFVIIDEQHRFGVHQRLML
CCCHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCHHCCCCEEEEE
TAKGSAPDMLVMTATPIPRTLVLTAFGDMDVSKLTEKPVGRQPITTAIVPMERMGELVER
EECCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHH
IRKAVSEDQKIYWICPLVEESEVVELTSAEERFESLKSVFGERIGLIHGRMSGAEKDEAM
HHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RAFKQGETRLLVATTVIEVGVDVPDATIIVIEHAERFGLSQLHQLRGRVGRGDKPSTCLL
HHHHCCCCEEEEEEEHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEE
LYKGPLGEIAQARLKVMRETEDGFRIAEEDLKLRGEGELLGTRQSGTPGFRLASIEAHGD
EEECCHHHHHHHHHHHHHCCCCCCEEEHHHHEECCCCCEEECCCCCCCCEEEEEECCCCH
LLEIARKDARYILASDPDLESERGQALRVLLYLFGRDEAIRLLRAG
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MFDPMRPSMLDPFFASVRSLSGIGPKVAVLLGKLLGTDVPGGEPKIGQLLFLPPHSIIDR
CCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHCC
RNRPGIAFAQEGAIVTLEVTVDQHQPAPKGRGNVPHRVFAHDDTGEIALTFFHAQLPWLQ
CCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCHHHH
KMLPEGETVIVSGKVEWFNGRASMVHPDYIASMDDAASLPLVEPVYPLTAGLSPKTLGRA
HHCCCCCEEEEEEEEEEECCCCCEECCHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
IKEALTRVPVLPEWIDAPLLAREGFPAFQQALNTLHQPEDPGDIALESITRRRLAYDEFL
HHHHHHHCCCCHHHHCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AGQLALALVRAKTRRLSGRPLEGTGNIVAEIMRHLPYRLTKAQEQAVREIITDLKSPQRM
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHH
LRLLQGDVGSGKTVVGLLSMAHAAESGGQSALMAPTEVLARQHFATIAPLAEKAGLKAAL
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEE
LTGREKGRERNAVLEGLKSGEIDIVIGTHALFQEKVEYHDLVFVIIDEQHRFGVHQRLML
CCCHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCHHCCCCEEEEE
TAKGSAPDMLVMTATPIPRTLVLTAFGDMDVSKLTEKPVGRQPITTAIVPMERMGELVER
EECCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHH
IRKAVSEDQKIYWICPLVEESEVVELTSAEERFESLKSVFGERIGLIHGRMSGAEKDEAM
HHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RAFKQGETRLLVATTVIEVGVDVPDATIIVIEHAERFGLSQLHQLRGRVGRGDKPSTCLL
HHHHCCCCEEEEEEEHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEE
LYKGPLGEIAQARLKVMRETEDGFRIAEEDLKLRGEGELLGTRQSGTPGFRLASIEAHGD
EEECCHHHHHHHHHHHHHCCCCCCEEEHHHHEECCCCCEEECCCCCCCCEEEEEECCCCH
LLEIARKDARYILASDPDLESERGQALRVLLYLFGRDEAIRLLRAG
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]