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The map label for this gene is katA

Identifier: 225686190

GI number: 225686190

Start: 335756

End: 337255

Strand: Direct

Name: katA

Synonym: BMEA_B0354

Alternate gene names: 225686190

Gene position: 335756-337255 (Clockwise)

Preceding gene: 225686187

Following gene: 225686191

Centisome position: 28.32

GC content: 57.0

Gene sequence:

>1500_bases
ATGACAGATCGCCCGATAATGACGACGAGTGCAGGCGCTCCGATACCGGACAACCAGAACTCGCTGACTGCCGGAGAGCG
CGGTCCCATCCTGATGCAGGATTATCAGCTTATTGAAAAGCTCTCGCACCAGAACCGTGAGCGCATTCCCGAACGTGCGG
TGCATGCCAAGGGCTGGGGTGCTTACGGCACGCTGACCATCACTGGCGATATTTCCAGATATACCAAAGCCAAGGTTTTG
CAGCCGGGTGCGCAGACGCCGATGCTGGCCCGCTTTTCCACCGTTGCCGGCGAGCTGGGCGCTGCCGATGCCGAACGTGA
CGTGCGCGGCTTTGCCCTCAAATTCTACACGCAAGAAGGCAATTGGGATCTGGTTGGCAACAATACGCCGGTCTTCTTCG
TGCGTGATCCGCTGAAGTTCCCGGATTTCATCCATACCCAGAAGCGCCACCCCAGGACCCATCTGCGTTCCGCAACCGCC
ATGTGGGATTTCTGGTCGCTGTCGCCGGAAAGCCTGCATCAGGTCACGATCCTGATGTCGGATCGCGGCCTGCCGACCGA
TGTGCGCCATATCAACGGTTACGGCTCGCACACCTATTCGTTCTGGAACGATGCCGGTGAGCGTTACTGGGTGAAGTTCC
ACTTCAAGACCATGCAGGGCCACAAGCACTGGACCAATGCGGAAGCCGAGCAGGTGATCGGCCGTACCCGTGAATCCACG
CAGGAAGATCTGTTTTCGGCCATCGAGAACGGCGAATTCCCGAAGTGGAAGGTGCAGGTTCAGATCATGCCGGAACTCGA
CGCCGACAAGACGCCGTATAACCCCTTCGATCTTACCAAAGTATGGCCCCATGCCGACTATCCGCCGATCGATATTGGCG
TGATGGAACTGAACCGCAACCCGGAAAACTATTTCACCGAGGTGGAGAATGCCGCCTTCTCGCCATCGAATATCGTTCCC
GGCATCGGCTTTTCGCCGGACAAGATGCTCCAGGCGCGTATCTTCTCCTATGCGGACGCGCATCGCCATCGCCTCGGCAC
GCATTACGAAAGCATTCCGGTCAACCAGCCGAAATGCCCGGTGCATCACTATCATCGCGACGGTCAGATGAATGTCTATG
GCGGCATCAAGACCGGCAATCCGGATGCCTATTACGAGCCGAATTCGTTCAATGGTCCGGTCGAACAGCCATCTGCCAAG
GAGCCGCCGCTGTGCATCTCCGGCAATGCGGATCGCTACAACCACCGTATCGGCAATGACGATTATTCACAGCCGCGCGC
GCTGTTCAATCTGTTCGATGCAGCGCAGAAGCAGCGCCTGTTCTCCAATATCGCGGCTGCGATGAAGGGCGTTCCAGGCT
TTATCGTTGAGCGTCAGCTTGGCCATTTCAAGTTGATCCACCCGGAATATGAAGCCGGTGTGCGCAAGGCGCTCAAGGAT
GCCCATGGTTATGACGCCAACACAATTGCCTTGAACGAAAAAATTACTGCAGCGGAATAG

Upstream 100 bases:

>100_bases
GACAAATGGTTTCGCCCCGGTGTGATGTTTCCCCGTCGCCTCACGCCTTCGGTAGCGCGAATAGTAGTTTAAAACGATGA
AATTGCAGGAGGATTATTCC

Downstream 100 bases:

>100_bases
TATATATATAATACAGTTATATTTAATATTGGTCGCCGGTTCATCCGGCGACTACTTTTTGTCTTGAATTTATATTTACC
GCCTATACTGTAAGTTGTAT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWGAYGTLTITGDISRYTKAKVL
QPGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEGNWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATA
MWDFWSLSPESLHQVTILMSDRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTREST
QEDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRNPENYFTEVENAAFSPSNIVP
GIGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCPVHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAK
EPPLCISGNADRYNHRIGNDDYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKD
AHGYDANTIALNEKITAAE

Sequences:

>Translated_499_residues
MTDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWGAYGTLTITGDISRYTKAKVL
QPGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEGNWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATA
MWDFWSLSPESLHQVTILMSDRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTREST
QEDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRNPENYFTEVENAAFSPSNIVP
GIGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCPVHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAK
EPPLCISGNADRYNHRIGNDDYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKD
AHGYDANTIALNEKITAAE
>Mature_498_residues
TDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWGAYGTLTITGDISRYTKAKVLQ
PGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEGNWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATAM
WDFWSLSPESLHQVTILMSDRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTRESTQ
EDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRNPENYFTEVENAAFSPSNIVPG
IGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCPVHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAKE
PPLCISGNADRYNHRIGNDDYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKDA
HGYDANTIALNEKITAAE

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family

Homologues:

Organism=Homo sapiens, GI4557014, Length=476, Percent_Identity=51.0504201680672, Blast_Score=488, Evalue=1e-138,
Organism=Escherichia coli, GI48994891, Length=481, Percent_Identity=42.8274428274428, Blast_Score=344, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI71998444, Length=478, Percent_Identity=51.0460251046025, Blast_Score=486, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=49.2662473794549, Blast_Score=459, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI25151141, Length=477, Percent_Identity=49.2662473794549, Blast_Score=459, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6320462, Length=500, Percent_Identity=42.6, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321525, Length=504, Percent_Identity=37.1031746031746, Blast_Score=311, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17981717, Length=469, Percent_Identity=49.2537313432836, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=42.9166666666667, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CATA_BRUAB (P0A327)

Other databases:

- EMBL:   U11439
- EMBL:   AE017224
- PIR:   A55227
- RefSeq:   YP_223581.1
- ProteinModelPortal:   P0A327
- SMR:   P0A327
- GeneID:   3341589
- GenomeReviews:   AE017224_GR
- KEGG:   bmb:BruAb2_0827
- HOGENOM:   HBG339355
- OMA:   IENAAFS
- PhylomeDB:   P0A327
- ProtClustDB:   CLSK886278
- BioCyc:   BABO262698:BRUAB2_0827-MONOMER
- BRENDA:   1.11.1.6
- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- Gene3D:   G3DSA:2.40.180.10
- PANTHER:   PTHR11465
- PRINTS:   PR00067

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; SSF56634 Catalase_N

EC number: =1.11.1.6

Molecular weight: Translated: 56447; Mature: 56316

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00437 CATALASE_1; PS00438 CATALASE_2; PS51402 CATALASE_3

Important sites: ACT_SITE 55-55 ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWG
CCCCCCEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYGTLTITGDISRYTKAKVLQPGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEG
CEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECC
NWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATAMWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEEEEEEE
DRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTREST
CCCCCCHHHHCCCCCCCCCHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QEDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRN
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCC
PENYFTEVENAAFSPSNIVPGIGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCP
CHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAKEPPLCISGNADRYNHRIGND
HHHCCCCCCEEEEECEECCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCC
DYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCCEEEECCHHHHHHHHHHHH
AHGYDANTIALNEKITAAE
HCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWG
CCCCCEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYGTLTITGDISRYTKAKVLQPGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEG
CEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECC
NWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATAMWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEEEEEEE
DRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTREST
CCCCCCHHHHCCCCCCCCCHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QEDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRN
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCC
PENYFTEVENAAFSPSNIVPGIGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCP
CHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAKEPPLCISGNADRYNHRIGND
HHHCCCCCCEEEEECEECCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCC
DYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCCEEEECCHHHHHHHHHHHH
AHGYDANTIALNEKITAAE
HCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961511