Click here to switch to the map view.

The map label for this gene is ycjS [H]

Identifier: 225686153

GI number: 225686153

Start: 293179

End: 294225

Strand: Direct

Name: ycjS [H]

Synonym: BMEA_B0309

Alternate gene names: 225686153

Gene position: 293179-294225 (Clockwise)

Preceding gene: 225686152

Following gene: 225686155

Centisome position: 24.73

GC content: 59.98

Gene sequence:

>1047_bases
ATGCGTCTTCTTATTCTTGGAACGGGCGGCATGGCGGAAAACCATGCGGAAGCCTTCAAGGCCATCGAGGGCGTGGAGGT
TGTGGCGGCTTGCGACGTTTCGGCGGTGCGTGTCGATGCTTTTTCGGAAAACCACGACATTCACAACCGCTTCACACGGC
TTGAGGATGCGCTGGCGTGGAACCGCTTCGATGCCGTTGCCAATGTAACGCCGGATGCGGTCCACCATCCCACCACGCTC
GCGCTGGTTGGCGCGGGCAAGCATGTCTTCTGTGAGAAGCCGCTGGCTGAAAGCTATGAGAAAGCCGCCGAAATGGCGGA
TGCGGCCCAGCAGGCGGGCGTGGTCAATATGGTCAACCTCACCTATCGCAATGTCGCGCCCTTGCAGAAGGCGCGCGAGA
TGGTGATGGCGGGCGAGATCGGCCAGGTGCGCCACTTCGAGGCATCCTATCTGCAAAGCTGGCTGGTGTCGAAGGCGTGG
GGCGACTGGAAGACGGAGAGCAAATGGCTTTGGCGGCTTTCCACCCGGCACGGGTCCAACGGCGTTCTGGGCGATGTGGG
CATTCATATTCTCGACTTCGCAACCTATGCCATCGGCAGCGATGTGGAACGGGCTTCAGCACATCTCAAGACCTTCGAGA
AGGCAGAGAACAACCATATCGGTGAATATGTGCTGGATGCCAACGACAGTTTCGTCATGATGGCGGAATATGCCAATGGG
GCGCTTGGCGTCATCCATGCAAGCCGGTGGGCGACGGGACACCTGAATGAATTGCGCCTGCGCATCCATGGCGACAAGGG
CGCGCTTGAAATCCTGCACACGCCCACCGGGTCGAGCCTGCGCGGTTCCATCGGAGAGGACATCGAAACGCCGGTCTGGC
GCGATATCGATGCAGGCACGGTAGAGACGAACTATCAGCGGTTTGCCCGTGCGGTCGCTGATGGAACGGAACTGGAGCCA
AGCTTCCGCCATGCCGCCAATCTCCAGCGCGTTCTTGACCATGCGATGCATGTGGACAAGCCATTGCCGGAAGTGGCGAC
CGGCTGA

Upstream 100 bases:

>100_bases
CCGCGCCGAACGTTCCCGTCGAAAAGGCGCTGGAGCCGATCGTGGAGCGCGGGCCAAAATTGCACAAGGCCGGTGAAGCC
GGTTATCGCTGAGGTACATC

Downstream 100 bases:

>100_bases
GCGGCTTCTTTTCCGTCGTCTGCGCGCGCCCATTTTAGGCAGTCTCCTCGCAGACAAGATTGCAAAACGCAGCTAGTTTA
TACCTGCCTTCAAGCCCCCG

Product: oxidoreductase domain-containing protein

Products: 2,4,6/3,5-pentahydroxycyclohexanone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRLLILGTGGMAENHAEAFKAIEGVEVVAACDVSAVRVDAFSENHDIHNRFTRLEDALAWNRFDAVANVTPDAVHHPTTL
ALVGAGKHVFCEKPLAESYEKAAEMADAAQQAGVVNMVNLTYRNVAPLQKAREMVMAGEIGQVRHFEASYLQSWLVSKAW
GDWKTESKWLWRLSTRHGSNGVLGDVGIHILDFATYAIGSDVERASAHLKTFEKAENNHIGEYVLDANDSFVMMAEYANG
ALGVIHASRWATGHLNELRLRIHGDKGALEILHTPTGSSLRGSIGEDIETPVWRDIDAGTVETNYQRFARAVADGTELEP
SFRHAANLQRVLDHAMHVDKPLPEVATG

Sequences:

>Translated_348_residues
MRLLILGTGGMAENHAEAFKAIEGVEVVAACDVSAVRVDAFSENHDIHNRFTRLEDALAWNRFDAVANVTPDAVHHPTTL
ALVGAGKHVFCEKPLAESYEKAAEMADAAQQAGVVNMVNLTYRNVAPLQKAREMVMAGEIGQVRHFEASYLQSWLVSKAW
GDWKTESKWLWRLSTRHGSNGVLGDVGIHILDFATYAIGSDVERASAHLKTFEKAENNHIGEYVLDANDSFVMMAEYANG
ALGVIHASRWATGHLNELRLRIHGDKGALEILHTPTGSSLRGSIGEDIETPVWRDIDAGTVETNYQRFARAVADGTELEP
SFRHAANLQRVLDHAMHVDKPLPEVATG
>Mature_348_residues
MRLLILGTGGMAENHAEAFKAIEGVEVVAACDVSAVRVDAFSENHDIHNRFTRLEDALAWNRFDAVANVTPDAVHHPTTL
ALVGAGKHVFCEKPLAESYEKAAEMADAAQQAGVVNMVNLTYRNVAPLQKAREMVMAGEIGQVRHFEASYLQSWLVSKAW
GDWKTESKWLWRLSTRHGSNGVLGDVGIHILDFATYAIGSDVERASAHLKTFEKAENNHIGEYVLDANDSFVMMAEYANG
ALGVIHASRWATGHLNELRLRIHGDKGALEILHTPTGSSLRGSIGEDIETPVWRDIDAGTVETNYQRFARAVADGTELEP
SFRHAANLQRVLDHAMHVDKPLPEVATG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082405, Length=228, Percent_Identity=27.6315789473684, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.1.1.18

Molecular weight: Translated: 38192; Mature: 38192

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLILGTGGMAENHAEAFKAIEGVEVVAACDVSAVRVDAFSENHDIHNRFTRLEDALAW
CEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
NRFDAVANVTPDAVHHPTTLALVGAGKHVFCEKPLAESYEKAAEMADAAQQAGVVNMVNL
HHHHHHHCCCCCHHCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEE
TYRNVAPLQKAREMVMAGEIGQVRHFEASYLQSWLVSKAWGDWKTESKWLWRLSTRHGSN
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCC
GVLGDVGIHILDFATYAIGSDVERASAHLKTFEKAENNHIGEYVLDANDSFVMMAEYANG
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCC
ALGVIHASRWATGHLNELRLRIHGDKGALEILHTPTGSSLRGSIGEDIETPVWRDIDAGT
EEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
VETNYQRFARAVADGTELEPSFRHAANLQRVLDHAMHVDKPLPEVATG
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure
MRLLILGTGGMAENHAEAFKAIEGVEVVAACDVSAVRVDAFSENHDIHNRFTRLEDALAW
CEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
NRFDAVANVTPDAVHHPTTLALVGAGKHVFCEKPLAESYEKAAEMADAAQQAGVVNMVNL
HHHHHHHCCCCCHHCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEE
TYRNVAPLQKAREMVMAGEIGQVRHFEASYLQSWLVSKAWGDWKTESKWLWRLSTRHGSN
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCC
GVLGDVGIHILDFATYAIGSDVERASAHLKTFEKAENNHIGEYVLDANDSFVMMAEYANG
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCC
ALGVIHASRWATGHLNELRLRIHGDKGALEILHTPTGSSLRGSIGEDIETPVWRDIDAGT
EEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
VETNYQRFARAVADGTELEPSFRHAANLQRVLDHAMHVDKPLPEVATG
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: myo-inositol; NAD+

Specific reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]