Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 225853500

GI number: 225853500

Start: 2013639

End: 2014508

Strand: Direct

Name: aroE [H]

Synonym: BMEA_A2131

Alternate gene names: 225853500

Gene position: 2013639-2014508 (Clockwise)

Preceding gene: 225853499

Following gene: 225853501

Centisome position: 94.73

GC content: 58.62

Gene sequence:

>870_bases
ATGGATGACAAAAGCATGGCCAGGGGGCGAAAGGCTTTCGTTACCGGATTTCCGATCAGGCATTCGCGTTCGCCGCTGAT
CCACGGTTTCTGGTTGAAGGAACTGGGCATTGACGGGTCTTATGAGGCTGTGGAAGTCAAGCCGGAAGATTTCTCCTCTT
TTGCAGCTTCGCTTGCCGCAAATGGCTTTGCGGGCGGAAATGTCACCATTCCCCACAAGGAGGCGGCCTATGCCGCTGCT
GAAAGCCTTGATGAAGCAGCCCGCGCCATCGGCGCGGTCAACACACTCTGGCTTGAAAATGGCAGGCTTTGCGGCGGCAA
CACCGATGCCTATGGTTTTGCCGCCAATCTGGATGCTTCCGCTCCCGGCTGGGACAAGGCTGATCGCGCTTTGGTTCTGG
GTGCCGGCGGGGCAAGCCGGGCGGTGGTTCATGCGCTTTTGTCGCGCGGCGTCTGTCATGTTTCGGTGGTGAACCGCACG
TTGAGCCGGGCGGAAGAACTGGCGGCGCATTTCGGCGCGCGCGTTTACGCCCATGGCTGGGATGAGGCGCAAGCTCTTGT
TTCCAATGCTGGTCTTATCGTCAACACGACCGCGCTCGGCATGAGCGGGCATGGCGAGGGACAGGATTTTCCGATCGACC
TTACATGCGCGCCGAAAGAGGCGGTGGCGACAGATATCGTCTATGTGCCGCTTAGAACAGCTTTCCTGAACAAAGCCGAA
AAAGCCGGTTTGAAGACAGTGGACGGGCTTGGCATGTTGCTGCATCAGGCTGTTCCGGGCTTTGAACGATGGTTCGGGCA
AAGGCCGCAGGTGACGCAGGCATTGCGAGAGCATATTCTGGCGGATATGGCGAAGGCTGGTGCGCTATGA

Upstream 100 bases:

>100_bases
GGAATTCAGCTTTTCGAGAAGATCGACGGCGATTATTTTACCATTGTCGGCCTGCCGCTCCTGCCGCTTCTGGCCGAACT
TCGCAGGGAAAAATGCATCG

Downstream 100 bases:

>100_bases
TTGTTCTCGGACTGACCGGCTCCATTGGAATGGGAAAAACCACTGCCGCCGGCATGTTTGCCGAGGCAGGTGTGCCGGTC
TATAGCGCCGACGATGCTGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAA
ESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRT
LSRAEELAAHFGARVYAHGWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAE
KAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL

Sequences:

>Translated_289_residues
MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAA
ESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRT
LSRAEELAAHFGARVYAHGWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAE
KAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
>Mature_289_residues
MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAA
ESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRT
LSRAEELAAHFGARVYAHGWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAE
KAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=277, Percent_Identity=39.7111913357401, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787983, Length=262, Percent_Identity=31.6793893129771, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=267, Percent_Identity=29.2134831460674, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30490; Mature: 30490

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAA
CCCHHHHCCCEEEEECCCCCCCCCCCEEEHHHHHHCCCCCCEEEEECCHHHHHHHHHHHC
NGFAGGNVTIPHKEAAYAAAESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDAS
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEECCCCCCCEEEECCCCC
APGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRTLSRAEELAAHFGARVYAHGW
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCEEEECCC
DEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAE
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHEEEEHHHHHHHHHHH
KAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
HCCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAA
CCCHHHHCCCEEEEECCCCCCCCCCCEEEHHHHHHCCCCCCEEEEECCHHHHHHHHHHHC
NGFAGGNVTIPHKEAAYAAAESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDAS
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEECCCCCCCEEEECCCCC
APGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRTLSRAEELAAHFGARVYAHGW
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCEEEECCC
DEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAE
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHEEEEHHHHHHHHHHH
KAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
HCCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA