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The map label for this gene is holA

Identifier: 225853488

GI number: 225853488

Start: 1999409

End: 2000452

Strand: Direct

Name: holA

Synonym: BMEA_A2118

Alternate gene names: NA

Gene position: 1999409-2000452 (Clockwise)

Preceding gene: 225853487

Following gene: 225853498

Centisome position: 94.06

GC content: 59.96

Gene sequence:

>1044_bases
ATGGCGCAGAAAAAAGCACACGAAGTCGACAGCTTTCTGGCGCGGTCGACAAGTTCATTTCCGGTCGTGCTTCTCTACGG
TCCCGACAAGGGGCTGGTGAATGAGCGCGCACGCCGTTATGCCGCAGCAAGCAAGCTGCCACTCGACGATCCCTTTGCCG
TGATCCGCATGGAGGCCGATGAGATCGAGGCCGATCCGGCAAAACTTGCCGACGAAGCCGGCACGATTTCCATGTTCGGC
GGGCAACGCCTGATCTGGATCAAGAACGCTGGCGGCCAGAAGAAGCTGGCCGAGGCCGTGAAACGGCTTGCAGCTGAGCC
CCCGCAGGAAACCTTCATTCTGATTGAAGCAGGCGATCTCAAAAAGGGTGCAGGCTTGCGCAGCGCCGTTGAGAATGCTT
CAGCAGGCATGGCCCTGCCCTGCTATTCCGATGATGCGCGCGGCATAGACGGCGTGATCGACGATATTCTTGCCGAGTGG
AAGATGCAGATCACGCTTGATGCGCGCCAGCTTCTGCGCGCCAGCCTGGGCGGCGACCGGCTGGCGACGCGCGGCGAGCT
GGAAAAACTCTGTCTCTATACCCGCGGCAAGGAACGCATCGACATTGATGATGTGCGTGAAGCGGTGGGCGATGTTGCGG
GGCTCTCAACCGACGAAGTGGTCGATGCGGTTCTGGCTGGGGATCTTCCGCGTTTTGAGATTGCGTTTGACCGGGTCGTC
AAATCCGGCACCGCGCCCTTTCTTCTGCTCACTGCGGCCATGCGCCAGTTCCAGCAGGTGCAGGCATTGCGCCATATCGC
CGATACCGAGCGCAAAAGCGCCTCCATGGTGGTCGCAAGCGCAAGACCGCCCATTTTTTTCAATCGAAAAAAGCTGATCG
AAACCGCCATTAGCCGCTGGACCGGCGAAAGCCTCACCCGCGTCATGGAACGGCTTCAGCGCGCCGTACTGGAAAGCCGC
CGAAACGCAGCCCTTTCCGTACCGATCATCCGCCAATGCCTGCTTGCGATCAGCGTAGAGTCGCTTCGCAATGCCAGGCG
ATAG

Upstream 100 bases:

>100_bases
CGCATCGGGTTTTGGGATACCAACCATTTTGTTTCACAGCCGCCCGTCAGTTCGACTGGCGGCTGTTTCGTTCGGACGCA
AATTGCGCTACTTAACCCGA

Downstream 100 bases:

>100_bases
AATCAGTTACTTCAAGTAATTCCACACTGTGAAGGCCTGTTTCAACAAACTGAAACAGGCCTTCACAGGACATATATCAT
AATTAAATTCTATCTAGCTT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Subunit; DNA-Directed DNA Polymerase III

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAQKKAHEVDSFLARSTSSFPVVLLYGPDKGLVNERARRYAAASKLPLDDPFAVIRMEADEIEADPAKLADEAGTISMFG
GQRLIWIKNAGGQKKLAEAVKRLAAEPPQETFILIEAGDLKKGAGLRSAVENASAGMALPCYSDDARGIDGVIDDILAEW
KMQITLDARQLLRASLGGDRLATRGELEKLCLYTRGKERIDIDDVREAVGDVAGLSTDEVVDAVLAGDLPRFEIAFDRVV
KSGTAPFLLLTAAMRQFQQVQALRHIADTERKSASMVVASARPPIFFNRKKLIETAISRWTGESLTRVMERLQRAVLESR
RNAALSVPIIRQCLLAISVESLRNARR

Sequences:

>Translated_347_residues
MAQKKAHEVDSFLARSTSSFPVVLLYGPDKGLVNERARRYAAASKLPLDDPFAVIRMEADEIEADPAKLADEAGTISMFG
GQRLIWIKNAGGQKKLAEAVKRLAAEPPQETFILIEAGDLKKGAGLRSAVENASAGMALPCYSDDARGIDGVIDDILAEW
KMQITLDARQLLRASLGGDRLATRGELEKLCLYTRGKERIDIDDVREAVGDVAGLSTDEVVDAVLAGDLPRFEIAFDRVV
KSGTAPFLLLTAAMRQFQQVQALRHIADTERKSASMVVASARPPIFFNRKKLIETAISRWTGESLTRVMERLQRAVLESR
RNAALSVPIIRQCLLAISVESLRNARR
>Mature_346_residues
AQKKAHEVDSFLARSTSSFPVVLLYGPDKGLVNERARRYAAASKLPLDDPFAVIRMEADEIEADPAKLADEAGTISMFGG
QRLIWIKNAGGQKKLAEAVKRLAAEPPQETFILIEAGDLKKGAGLRSAVENASAGMALPCYSDDARGIDGVIDDILAEWK
MQITLDARQLLRASLGGDRLATRGELEKLCLYTRGKERIDIDDVREAVGDVAGLSTDEVVDAVLAGDLPRFEIAFDRVVK
SGTAPFLLLTAAMRQFQQVQALRHIADTERKSASMVVASARPPIFFNRKKLIETAISRWTGESLTRVMERLQRAVLESRR
NAALSVPIIRQCLLAISVESLRNARR

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 38055; Mature: 37924

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKKAHEVDSFLARSTSSFPVVLLYGPDKGLVNERARRYAAASKLPLDDPFAVIRMEAD
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHH
EIEADPAKLADEAGTISMFGGQRLIWIKNAGGQKKLAEAVKRLAAEPPQETFILIEAGDL
HCCCCHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
KKGAGLRSAVENASAGMALPCYSDDARGIDGVIDDILAEWKMQITLDARQLLRASLGGDR
CCCCCHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHEEEECHHHHHHHHCCCCC
LATRGELEKLCLYTRGKERIDIDDVREAVGDVAGLSTDEVVDAVLAGDLPRFEIAFDRVV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
KSGTAPFLLLTAAMRQFQQVQALRHIADTERKSASMVVASARPPIFFNRKKLIETAISRW
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEECHHHHHHHHHHHC
TGESLTRVMERLQRAVLESRRNAALSVPIIRQCLLAISVESLRNARR
CCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQKKAHEVDSFLARSTSSFPVVLLYGPDKGLVNERARRYAAASKLPLDDPFAVIRMEAD
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHH
EIEADPAKLADEAGTISMFGGQRLIWIKNAGGQKKLAEAVKRLAAEPPQETFILIEAGDL
HCCCCHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
KKGAGLRSAVENASAGMALPCYSDDARGIDGVIDDILAEWKMQITLDARQLLRASLGGDR
CCCCCHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHEEEECHHHHHHHHCCCCC
LATRGELEKLCLYTRGKERIDIDDVREAVGDVAGLSTDEVVDAVLAGDLPRFEIAFDRVV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHH
KSGTAPFLLLTAAMRQFQQVQALRHIADTERKSASMVVASARPPIFFNRKKLIETAISRW
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEECHHHHHHHHHHHC
TGESLTRVMERLQRAVLESRRNAALSVPIIRQCLLAISVESLRNARR
CCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA