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The map label for this gene is hisC [H]

Identifier: 225853423

GI number: 225853423

Start: 1933372

End: 1934478

Strand: Direct

Name: hisC [H]

Synonym: BMEA_A2044

Alternate gene names: 225853423

Gene position: 1933372-1934478 (Clockwise)

Preceding gene: 225853422

Following gene: 225853424

Centisome position: 90.95

GC content: 59.08

Gene sequence:

>1107_bases
ATGACCGACATGCAGAAACCTACCCGTCCCCAGCCCAAGGCAGGCGTGCTTGACATTGCAGCCTATGTACCCGGCAAGGA
ACATGTGGAAGGCGTTGCCAAGGTCTATAAGCTCTCCTCCAACGAAACCCCGCTTGGACCAAGCCCCCATGCCAGGGAAG
CCTACCGGCATGCGGGCGAAAAGCTTGAGCTTTACCCGGACGGGCAGGCACTGGCGCTGCGGCAGGCGATTGCGGAAACG
CAGGGGCTCAACATTTCCAACATTCTGTGCGGCAACGGATCCGACGAATTGCTGGGCCTTCTCTGCCAGACCTATCTTGC
CCCCGGTGACGAAACCATCATCACCGAGCACGGCTTTGCCGTTTACAAGATCCAGACGCTCGCAGCCGGCGCCACCCCCG
TCACGGTGAAGGAAAAGAACGAACGCATCGATGTGGACGCCATCCTCGCAGGTGTGACGGCGCGCACAAAAATCGTCTTC
ATCGCCAATCCGGCCAACCCGACCGGCACTTATCTGCCTTTTGAGGAAGTGCGCCGCCTCCATGCGGGCCTGCCGCAGCA
TGTTCTGCTGGTGCTCGACGCCGCCTATGCCGAATATGTGCGCCGCAACGATTATGAAGCCGGGCTGGAACTCGTTTCAT
CCAATGAAAACGTGGTGATGATGCGCACTTTCTCGAAGATTCACGGCCTGCCCGGCCTGCGCATCGGCTGGATTTATGCG
CCGCTCCACATCATCGACGCCATGAACCGCATCCGCGGCCCCTTCAACATGAATTCCGCCGCGATTGCTGCGGGCGCCGC
CGCGATCCGCGATCGTGCACATGTCGAAAAATCGGTCGCCTATAACGAGAAATGGCTTGCCTGGCTCACGGAAGAATTCA
CCAGGCTCGGTCTGCGGGTTACACCTTCCGTGACGAACTTCCTGCTCATTCATTTCCCCGATGATGCCGCCCATTCGGCA
GACAAGGCCGATGAATGGCTATCGAGGCGCGGCTATATTCTCCGCCGTGTCGGGGGCTATGGTTTCCCCAATGCACTGCG
CATGACGGTGGGACCAGAAGAAGCCAATCGCGGTGTGGTAGCCGCCCTCACAGAATTTCTGAAGTAA

Upstream 100 bases:

>100_bases
TCGCAAGCCTTCCCGAACAAGGTTTTTCTCGACTTGGGCGCGGCGGCGGGATATGCCGCCAAGGTAGTTTTAACGTGGAC
CTTTTGGCGGAGCCAAAATC

Downstream 100 bases:

>100_bases
ACAAATGTCCACAATCCACTTCGATAAAATCACGCTGATCGGTATCGGCCTTATCGGTTCCTCGCTGGCGCGCGTCATTC
GCCGCGAGGGCCTGGCAACG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTDMQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGEKLELYPDGQALALRQAIAET
QGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFAVYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVF
IANPANPTGTYLPFEEVRRLHAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYA
PLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRVTPSVTNFLLIHFPDDAAHSA
DKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVVAALTEFLK

Sequences:

>Translated_368_residues
MTDMQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGEKLELYPDGQALALRQAIAET
QGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFAVYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVF
IANPANPTGTYLPFEEVRRLHAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYA
PLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRVTPSVTNFLLIHFPDDAAHSA
DKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVVAALTEFLK
>Mature_367_residues
TDMQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGEKLELYPDGQALALRQAIAETQ
GLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFAVYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVFI
ANPANPTGTYLPFEEVRRLHAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYAP
LHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRVTPSVTNFLLIHFPDDAAHSAD
KADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVVAALTEFLK

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=340, Percent_Identity=27.6470588235294, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322075, Length=396, Percent_Identity=25.5050505050505, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40345; Mature: 40213

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGE
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
KLELYPDGQALALRQAIAETQGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFA
EEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCEE
VYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVFIANPANPTGTYLPFEEVRRL
EEEEEEHHCCCCCEEEECCCCCCCHHHHHHCCEEEEEEEEEECCCCCCCCCCCHHHHHHH
HAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYA
HCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEHHHHCCCCCCEEHHHHH
PLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
TPSVTNFLLIHFPDDAAHSADKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVV
CCCCCCEEEEECCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCHHCCCHH
AALTEFLK
HHHHHHHC
>Mature Secondary Structure 
TDMQKPTRPQPKAGVLDIAAYVPGKEHVEGVAKVYKLSSNETPLGPSPHAREAYRHAGE
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
KLELYPDGQALALRQAIAETQGLNISNILCGNGSDELLGLLCQTYLAPGDETIITEHGFA
EEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCEE
VYKIQTLAAGATPVTVKEKNERIDVDAILAGVTARTKIVFIANPANPTGTYLPFEEVRRL
EEEEEEHHCCCCCEEEECCCCCCCHHHHHHCCEEEEEEEEEECCCCCCCCCCCHHHHHHH
HAGLPQHVLLVLDAAYAEYVRRNDYEAGLELVSSNENVVMMRTFSKIHGLPGLRIGWIYA
HCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEHHHHCCCCCCEEHHHHH
PLHIIDAMNRIRGPFNMNSAAIAAGAAAIRDRAHVEKSVAYNEKWLAWLTEEFTRLGLRV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
TPSVTNFLLIHFPDDAAHSADKADEWLSRRGYILRRVGGYGFPNALRMTVGPEEANRGVV
CCCCCCEEEEECCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCHHCCCHH
AALTEFLK
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA