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The map label for this gene is nudG [H]

Identifier: 225853377

GI number: 225853377

Start: 1888302

End: 1888718

Strand: Reverse

Name: nudG [H]

Synonym: BMEA_A1996

Alternate gene names: 225853377

Gene position: 1888718-1888302 (Counterclockwise)

Preceding gene: 225853378

Following gene: 225853376

Centisome position: 88.85

GC content: 59.47

Gene sequence:

>417_bases
ATGACCGAAGTGAAGAAACGGCGCATGCTTCTTGTCGTGGCCTGTGCCCTTGTGGATCAGGACGGGCGGGTGCTTCTGGC
GCAGCGTCCCGAAGGCAAGCAGCTTGCGGGCCTGTGGGAATTTCCCGGCGGCAAGGTGGAGCCGGGTGAGATGCCGGAAG
AAACCCTGATTCGCGAATTGCAGGAAGAGATCGGCATCACGACAAAAATCCCCTGCCTCGCACCGCTGACTTTCGCGAGT
TACACATATGATGATTTTCACCTTCTGATGCCGCTCTATGTCTGCCGCCGTTTCGAGGGCGTTGCGCGCGGGCTGGAAGG
GCAGGCGCTGAAATGGGTGCGCCCGAAGGACATGCGCGATTATCCGATGCCTCCGGCGGATGAGCCGCTCATTCCGTTTC
TGGTCGATCTGCTTTGA

Upstream 100 bases:

>100_bases
GGCTGCAAATCGAGGCGGATAATGTGGCCGGACTTGCCCTTTATGAAAGGTTCGGCTTTCAGGAGGCCTATGGTTACGCT
TATCGGGAGAATAGCCTGAA

Downstream 100 bases:

>100_bases
CAGGCGGGTCCGGCTGAAATAGCTGCCAATTTCTTACTATTTTCAGCATGCGTTAATCGATGATTCACTCCGCTGCGGCA
TTGTCCGAACCAGCCCCCCG

Product: mutator MutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTEVKKRRMLLVVACALVDQDGRVLLAQRPEGKQLAGLWEFPGGKVEPGEMPEETLIRELQEEIGITTKIPCLAPLTFAS
YTYDDFHLLMPLYVCRRFEGVARGLEGQALKWVRPKDMRDYPMPPADEPLIPFLVDLL

Sequences:

>Translated_138_residues
MTEVKKRRMLLVVACALVDQDGRVLLAQRPEGKQLAGLWEFPGGKVEPGEMPEETLIRELQEEIGITTKIPCLAPLTFAS
YTYDDFHLLMPLYVCRRFEGVARGLEGQALKWVRPKDMRDYPMPPADEPLIPFLVDLL
>Mature_137_residues
TEVKKRRMLLVVACALVDQDGRVLLAQRPEGKQLAGLWEFPGGKVEPGEMPEETLIRELQEEIGITTKIPCLAPLTFASY
TYDDFHLLMPLYVCRRFEGVARGLEGQALKWVRPKDMRDYPMPPADEPLIPFLVDLL

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=132, Percent_Identity=40.1515151515151, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1786288, Length=130, Percent_Identity=33.0769230769231, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15699; Mature: 15568

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVKKRRMLLVVACALVDQDGRVLLAQRPEGKQLAGLWEFPGGKVEPGEMPEETLIREL
CCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
QEEIGITTKIPCLAPLTFASYTYDDFHLLMPLYVCRRFEGVARGLEGQALKWVRPKDMRD
HHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCC
YPMPPADEPLIPFLVDLL
CCCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
TEVKKRRMLLVVACALVDQDGRVLLAQRPEGKQLAGLWEFPGGKVEPGEMPEETLIREL
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
QEEIGITTKIPCLAPLTFASYTYDDFHLLMPLYVCRRFEGVARGLEGQALKWVRPKDMRD
HHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCC
YPMPPADEPLIPFLVDLL
CCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]