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The map label for this gene is sucD [H]

Identifier: 225853363

GI number: 225853363

Start: 1876412

End: 1877314

Strand: Reverse

Name: sucD [H]

Synonym: BMEA_A1982

Alternate gene names: 225853363

Gene position: 1877314-1876412 (Counterclockwise)

Preceding gene: 225853364

Following gene: 225853361

Centisome position: 88.32

GC content: 60.47

Gene sequence:

>903_bases
ATGTCCATTCTCGTCAACAAGGACACCAAGGTTCTCGTGCAGGGCCTGACCGGCAAGACCGGCACTTTCCACACCGAACA
GGCGCTTGCCTATTACGGCACGCAGATGGTCGGCGGTATCCATCCGAAGAAGGGTGGCGAAACCTGGGAAGGTTCCAAGG
GTGAAAAGCTTCCGATCTTCGCAACTGTTGCCGAAGGCAAGGAGCGCACCGGCGCCGACGCTTCCGTGATCTATGTTCCG
CCAGCAGGCGCAGCAGACGCGATCATCGAAGCGATTGAAGCTGAAATCGGTTTCATCGTCTGCATCACCGAAGGCATTCC
GGTCATGGACATAGTTCGCGTCAAGGAGCGTCTGGAACGCTCGAAGTCGCGCCTGCTCGGCCCCAACTGCCCCGGCATCC
TGACCCCTGAAGAATGCAAGATCGGCATCATGCCGGGCAATATCTTCAAGAAGGGTTCGGTGGGTGTTGTATCCCGCTCC
GGCACGCTTACCTATGAGGCAGTGTTCCAGACCTCGAACGAGGGCCTCGGCCAGACCACCGCTGTCGGCATCGGCGGCGA
CCCGGTCAAGGGTACCGAGTTCATCGACGTGCTGGAAATGTTCCTGGCCGACGACGAAACCAAGTCGATCGTCATGATCG
GTGAAATCGGCGGTTCGGCTGAAGAAGATGCGGCGCAGTTCCTGAAAGACGAAGCCAAGCGCGGCCGCAAGAAGCCGATG
GTCGGCTTCATTGCCGGTCGTACGGCTCTGGCCGGGCGCACCATGGGCCATGCAGGCGCCGTGATTTCGGGCGGCAAGGG
CGGCGCGGAAGACAAGATTGCGGCTATGGAGTCGGCTGGCATTCGCGTGTCGCCGTCGCCGGCACAGCTTGGCAAGACGC
TGGTTGAAGTCCTCAAGGGCTGA

Upstream 100 bases:

>100_bases
CAAGAAGATCATCAACGAGAGCGGCCTGAACGTCATTTCGGCCGACGATCTCGACGATGCGGCGCAGAAGATCGTCGCTG
CAGTGAAGGGGAATTAAGGC

Downstream 100 bases:

>100_bases
GATCGCGTGTCAATCTGAATATCCCGGCTGCGGCGAAAGCCGCTGCCGGGTTTGGCATGAGGATCGGGACCTTCCGATCA
TGATATTGCGGCGCGGAATG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSILVNKDTKVLVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWEGSKGEKLPIFATVAEGKERTGADASVIYVP
PAGAADAIIEAIEAEIGFIVCITEGIPVMDIVRVKERLERSKSRLLGPNCPGILTPEECKIGIMPGNIFKKGSVGVVSRS
GTLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIVMIGEIGGSAEEDAAQFLKDEAKRGRKKPM
VGFIAGRTALAGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPAQLGKTLVEVLKG

Sequences:

>Translated_300_residues
MSILVNKDTKVLVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWEGSKGEKLPIFATVAEGKERTGADASVIYVP
PAGAADAIIEAIEAEIGFIVCITEGIPVMDIVRVKERLERSKSRLLGPNCPGILTPEECKIGIMPGNIFKKGSVGVVSRS
GTLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIVMIGEIGGSAEEDAAQFLKDEAKRGRKKPM
VGFIAGRTALAGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPAQLGKTLVEVLKG
>Mature_299_residues
SILVNKDTKVLVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWEGSKGEKLPIFATVAEGKERTGADASVIYVPP
AGAADAIIEAIEAEIGFIVCITEGIPVMDIVRVKERLERSKSRLLGPNCPGILTPEECKIGIMPGNIFKKGSVGVVSRSG
TLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIVMIGEIGGSAEEDAAQFLKDEAKRGRKKPMV
GFIAGRTALAGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPAQLGKTLVEVLKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=63.3898305084746, Blast_Score=305, Evalue=5e-83,
Organism=Homo sapiens, GI38569423, Length=317, Percent_Identity=26.4984227129338, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38569421, Length=317, Percent_Identity=26.4984227129338, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786949, Length=299, Percent_Identity=58.5284280936455, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17553126, Length=300, Percent_Identity=61.3333333333333, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17550194, Length=300, Percent_Identity=58.6666666666667, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=318, Percent_Identity=26.7295597484277, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=310, Percent_Identity=27.0967741935484, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=300, Percent_Identity=50, Blast_Score=277, Evalue=1e-75,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=60.472972972973, Blast_Score=359, Evalue=1e-99,
Organism=Drosophila melanogaster, GI28574296, Length=299, Percent_Identity=62.5418060200669, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI281363477, Length=279, Percent_Identity=28.3154121863799, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281363475, Length=279, Percent_Identity=28.3154121863799, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363473, Length=279, Percent_Identity=28.3154121863799, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31234; Mature: 31103

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVNKDTKVLVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWEGSKGEKLPIF
CEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
ATVAEGKERTGADASVIYVPPAGAADAIIEAIEAEIGFIVCITEGIPVMDIVRVKERLER
EEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
SKSRLLGPNCPGILTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYEAVFQTSNEGLGQTT
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
AVGIGGDPVKGTEFIDVLEMFLADDETKSIVMIGEIGGSAEEDAAQFLKDEAKRGRKKPM
EEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
VGFIAGRTALAGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPAQLGKTLVEVLKG
EEEEECCHHHCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILVNKDTKVLVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWEGSKGEKLPIF
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
ATVAEGKERTGADASVIYVPPAGAADAIIEAIEAEIGFIVCITEGIPVMDIVRVKERLER
EEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
SKSRLLGPNCPGILTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYEAVFQTSNEGLGQTT
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
AVGIGGDPVKGTEFIDVLEMFLADDETKSIVMIGEIGGSAEEDAAQFLKDEAKRGRKKPM
EEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
VGFIAGRTALAGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPAQLGKTLVEVLKG
EEEEECCHHHCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]