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The map label for this gene is ydfD [H]

Identifier: 225853331

GI number: 225853331

Start: 1845204

End: 1846697

Strand: Direct

Name: ydfD [H]

Synonym: BMEA_A1947

Alternate gene names: 225853331

Gene position: 1845204-1846697 (Clockwise)

Preceding gene: 225853329

Following gene: 225853334

Centisome position: 86.8

GC content: 61.98

Gene sequence:

>1494_bases
ATGGTGGTACAGATGATTCCGATCGGCCTGCTGCATAGCTTGGAAGCTGTCGAAGCCGCCTATACAGGCGGGGAAATCGG
GCGTGGCGAACAAGGCGCCCCCGCCGACAGGATGCCACTCGTCGAAAAGGTCATGGGCATCATTCGCGGCCGCATCACCG
CGATGAGCCTCGCACCCGGGGCGAGGCTGCCCTCGATCCGCCGCCTTGCGGAAACGATGAACGTCTCGAAATCGACTGTG
GTGGAAGCCTATGACCGGCTGGTCGCGGAAGGTATCATCCAGTCGCGGCGCGGCGCGGGCTTTTATGTTTCCGAGCGGGC
GCGCCAGCCATTCTCGCTTGCCGCCACCGCCCCGCACAAGGACCGGCAGATCGATCCGTTCTGGGTCATGCGGCAATCGC
TCGAAGCGGAAAGCCGAACCCTCAAGCCCGGCTGCGGCTGGCTACCCGATGGATGGTTGCCGCAGGAGGCCCTTCGCCGG
GCGCTGCGCACCATTGCCCGCGACGACCAGAGCAACCTCACCACTTATGGCGAGCCGCTTGGCTTCCGCCCCTTGCGCCA
GCATCTCGCCCACCGCCTTGGCGAGCAGGGCATCGACATTGCGGGCGGGGAAATCCTGCTCACCGATTCCGGCACGCAGG
CCATTGATCTCATCTGCCGCTATCTCCTCCAGCCCGGCGACACGGTGCTGGTGGACGATCCATGCTATTTCAATTTTCAG
GCGGTGCTGCTCACCCATCGGGTAAAACTGGTTGGCGTGCCTTACACCCATTCCGGGCCAGATCTCGACGCCTTCGCCAA
TGCGGCAACCGAACACGCGCCCAAGCTCTATATCTCCAATGCCGGGCTGCATAACCCGACCGGCGGCATCATGACGCCTG
CCACGGCCCACCGGCTTTTAAAGCTTGCCGAAGCCCATGGCATCACTCTGGTCGAAGACAATATCTTTGGTGATTTCCAC
CCCTCGCCCACCCCGCTTCTGGCAGAGCTGGACGGGTTTGAGCGTGTGCTGCACATTGGCAGTTTCTCCAAGACGCTGTC
GGCAGCCGCGCGCGTTGGCTATATTGCCGGACGCCGGGACTGGATCGAAGGGCTTACCGACCTCAAACTCGCCACCAGCT
TCGGCTGCAATGCGCTCTCGCCGCAGATCGTCCATGCACTTCTGATCGACGGCACCTATCGGCGGCATATTGAAAGCCTG
CGCACCAGGCTTGCAGATGCCATGACACTGACCGCAAACCGGCTGAAGGCAACCGGCCTGGACTTATGGACGAAACCGCA
AGGCGGCATGTTTTTATGGGCGCGGCTTCCCGACGGGATGGATTCCGGACCTGTTGCCCGTCATGCTCTGGAAAAAGGCG
TCGTGCTTGCACCGGGAAATGTCTTCAGCCCCTCATGCACGGCGGCAGGCTTTCTGCGTTTCAATGTCGCCCAGTCCGCA
GACCCTTATATTTACGCGGTTCTGCGTGAGGCCATGAAGGCCGCAAGCTCCTGA

Upstream 100 bases:

>100_bases
TTCTGCAAAATCGTATATGGCTTTTACGGACAATGCCGTGAACTCGTCTAAAAAATCAGAGACAGTTTCCAGACAATTCT
GGCAAACTGTACTGGTATGA

Downstream 100 bases:

>100_bases
AATTCACCGCATTATATAGTTCCAGAGCATTTCCTGTTTTGATTAAACCGCTGGAAAAGCTTTAGAAATCATCATCGCCC
GTGGGCACCAGTATTTCGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MVVQMIPIGLLHSLEAVEAAYTGGEIGRGEQGAPADRMPLVEKVMGIIRGRITAMSLAPGARLPSIRRLAETMNVSKSTV
VEAYDRLVAEGIIQSRRGAGFYVSERARQPFSLAATAPHKDRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRR
ALRTIARDDQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDTVLVDDPCYFNFQ
AVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTGGIMTPATAHRLLKLAEAHGITLVEDNIFGDFH
PSPTPLLAELDGFERVLHIGSFSKTLSAAARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESL
RTRLADAMTLTANRLKATGLDLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTAAGFLRFNVAQSA
DPYIYAVLREAMKAASS

Sequences:

>Translated_497_residues
MVVQMIPIGLLHSLEAVEAAYTGGEIGRGEQGAPADRMPLVEKVMGIIRGRITAMSLAPGARLPSIRRLAETMNVSKSTV
VEAYDRLVAEGIIQSRRGAGFYVSERARQPFSLAATAPHKDRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRR
ALRTIARDDQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDTVLVDDPCYFNFQ
AVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTGGIMTPATAHRLLKLAEAHGITLVEDNIFGDFH
PSPTPLLAELDGFERVLHIGSFSKTLSAAARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESL
RTRLADAMTLTANRLKATGLDLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTAAGFLRFNVAQSA
DPYIYAVLREAMKAASS
>Mature_497_residues
MVVQMIPIGLLHSLEAVEAAYTGGEIGRGEQGAPADRMPLVEKVMGIIRGRITAMSLAPGARLPSIRRLAETMNVSKSTV
VEAYDRLVAEGIIQSRRGAGFYVSERARQPFSLAATAPHKDRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRR
ALRTIARDDQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDTVLVDDPCYFNFQ
AVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTGGIMTPATAHRLLKLAEAHGITLVEDNIFGDFH
PSPTPLLAELDGFERVLHIGSFSKTLSAAARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESL
RTRLADAMTLTANRLKATGLDLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTAAGFLRFNVAQSA
DPYIYAVLREAMKAASS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=354, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI33469970, Length=354, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1790797, Length=447, Percent_Identity=30.2013422818792, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787710, Length=454, Percent_Identity=27.9735682819383, Blast_Score=157, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356535, Length=352, Percent_Identity=23.0113636363636, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53990; Mature: 53990

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVQMIPIGLLHSLEAVEAAYTGGEIGRGEQGAPADRMPLVEKVMGIIRGRITAMSLAPG
CEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
ARLPSIRRLAETMNVSKSTVVEAYDRLVAEGIIQSRRGAGFYVSERARQPFSLAATAPHK
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECCCCC
DRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRRALRTIARDDQSNLTTYGEPL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDTVLVDDPCYFNFQ
CCHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHH
AVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTGGIMTPATAHRLL
HHHHHHCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHH
KLAEAHGITLVEDNIFGDFHPSPTPLLAELDGFERVLHIGSFSKTLSAAARVGYIAGRRD
HHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
WIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESLRTRLADAMTLTANRLKATGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTAAGFLRFNVAQSA
CEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCEEECCCCCCCCCCCHHHEEEEEECCCC
DPYIYAVLREAMKAASS
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVQMIPIGLLHSLEAVEAAYTGGEIGRGEQGAPADRMPLVEKVMGIIRGRITAMSLAPG
CEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
ARLPSIRRLAETMNVSKSTVVEAYDRLVAEGIIQSRRGAGFYVSERARQPFSLAATAPHK
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECCCCC
DRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRRALRTIARDDQSNLTTYGEPL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDTVLVDDPCYFNFQ
CCHHHHHHHHHHHCCCCCEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHH
AVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTGGIMTPATAHRLL
HHHHHHCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHH
KLAEAHGITLVEDNIFGDFHPSPTPLLAELDGFERVLHIGSFSKTLSAAARVGYIAGRRD
HHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
WIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESLRTRLADAMTLTANRLKATGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTAAGFLRFNVAQSA
CEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCEEECCCCCCCCCCCHHHEEEEEECCCC
DPYIYAVLREAMKAASS
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]