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The map label for this gene is pdxY [H]

Identifier: 225853272

GI number: 225853272

Start: 1780730

End: 1781626

Strand: Reverse

Name: pdxY [H]

Synonym: BMEA_A1879

Alternate gene names: 225853272

Gene position: 1781626-1780730 (Counterclockwise)

Preceding gene: 225853273

Following gene: 225853271

Centisome position: 83.81

GC content: 61.76

Gene sequence:

>897_bases
ATGACGCTTCCTGCGCCTTCGGATGCGACAACCGTTATTGTCATCTCAAGCCATGTCGTGCGCGGTTCGGTGGGCAATCG
CGCGGCTGTCTTCGCTTTGGAAACACTTGGCTTTCCGGTCTGGGCAGTGCCGACGGTGGTGCTGCCATGGCATCCGGGCC
ATGGGGTTCCGGGTGCTCCGGCCGGACGCATCGTGCCGCCTGCGGATGAATTTGCCCGCCTCATGCAGGACTTGCAGCGC
GCGCCATGGCTGAACGAGGTGGGCGCGGTGCTGACCGGCTATCTTGGCCATCCCGAACAGGCGGCGGTGGTGGCCAGTCT
GGTCAAGGCCGTGAAGGCGAACAATCCCGAAGCAGTCTATCTCTGCGATCCGGTCATCGGGGACGAGAAAGGCCTTTATG
TGCCCGAGGCGACTGCCATGGGCATTCGCGACAGGCTTCTGCCGCTTGCCGATATCGCGACGCCCAATCGTTTCGAGCTT
TCCTGGCTGACCGGTGTGCCACTTGAAGACAATAAGGCGCTTATGGAGGCAGCCCTCGATGCGGGGCCTGCCGCCATGCT
GGTGACTTCCGCCTTCCCGTTTATGAACGGCAGTATCGGCAATATTCTGCTGACGCCGACGCTTGCCCTGATGGCCGAAC
ATCGCCGGGTGGACGGGCCGACCAACGGGCTTGGCGATTTGACATCTGCCGTCTTTCTGGCGCGCTACCTTTCCGGGCTT
TCGGAAGAAAAGACGCTGCAAAGCACAACCGCTGCCGTGTTTGAAATCATGGCGCGCTCGGCCAAGCGTGGAGCGGATGA
ATTGATGCTGGAAGCCGACGCATCAAGCCTTGCCACGCCAATGGCCATGGTGCAGACGCGGCGGCTTCTTCATCCGACCA
AAGGGCTGCGGACCTGA

Upstream 100 bases:

>100_bases
GAACTCTGGGCCACCCGTGTCGGGCGCGGGCTTGGCCTTCTCATAACGCTGGCGATCATCGTCTGGCTCATTTCCTATCT
CATGCAAAGCCAGGTATAAA

Downstream 100 bases:

>100_bases
ATGGTGAAATTCCTCCCATATGCGCCATGCCGAACATGGTGCCTGCTGGCTGGCGCATGGCGATATGGGCTTGAGAATGC
ACATGAAACCTGTGTGAAAA

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTLPAPSDATTVIVISSHVVRGSVGNRAAVFALETLGFPVWAVPTVVLPWHPGHGVPGAPAGRIVPPADEFARLMQDLQR
APWLNEVGAVLTGYLGHPEQAAVVASLVKAVKANNPEAVYLCDPVIGDEKGLYVPEATAMGIRDRLLPLADIATPNRFEL
SWLTGVPLEDNKALMEAALDAGPAAMLVTSAFPFMNGSIGNILLTPTLALMAEHRRVDGPTNGLGDLTSAVFLARYLSGL
SEEKTLQSTTAAVFEIMARSAKRGADELMLEADASSLATPMAMVQTRRLLHPTKGLRT

Sequences:

>Translated_298_residues
MTLPAPSDATTVIVISSHVVRGSVGNRAAVFALETLGFPVWAVPTVVLPWHPGHGVPGAPAGRIVPPADEFARLMQDLQR
APWLNEVGAVLTGYLGHPEQAAVVASLVKAVKANNPEAVYLCDPVIGDEKGLYVPEATAMGIRDRLLPLADIATPNRFEL
SWLTGVPLEDNKALMEAALDAGPAAMLVTSAFPFMNGSIGNILLTPTLALMAEHRRVDGPTNGLGDLTSAVFLARYLSGL
SEEKTLQSTTAAVFEIMARSAKRGADELMLEADASSLATPMAMVQTRRLLHPTKGLRT
>Mature_297_residues
TLPAPSDATTVIVISSHVVRGSVGNRAAVFALETLGFPVWAVPTVVLPWHPGHGVPGAPAGRIVPPADEFARLMQDLQRA
PWLNEVGAVLTGYLGHPEQAAVVASLVKAVKANNPEAVYLCDPVIGDEKGLYVPEATAMGIRDRLLPLADIATPNRFELS
WLTGVPLEDNKALMEAALDAGPAAMLVTSAFPFMNGSIGNILLTPTLALMAEHRRVDGPTNGLGDLTSAVFLARYLSGLS
EEKTLQSTTAAVFEIMARSAKRGADELMLEADASSLATPMAMVQTRRLLHPTKGLRT

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=306, Percent_Identity=34.3137254901961, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1787924, Length=279, Percent_Identity=32.9749103942652, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788758, Length=272, Percent_Identity=32.3529411764706, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17507759, Length=290, Percent_Identity=30, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17507757, Length=294, Percent_Identity=29.2517006802721, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320806, Length=242, Percent_Identity=32.2314049586777, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324354, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553007, Length=301, Percent_Identity=29.9003322259136, Blast_Score=121, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31528; Mature: 31397

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPAPSDATTVIVISSHVVRGSVGNRAAVFALETLGFPVWAVPTVVLPWHPGHGVPGAP
CCCCCCCCCEEEEEEECEEEECCCCCCEEEEEHHHHCCCHHHCCEEEEECCCCCCCCCCC
AGRIVPPADEFARLMQDLQRAPWLNEVGAVLTGYLGHPEQAAVVASLVKAVKANNPEAVY
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEE
LCDPVIGDEKGLYVPEATAMGIRDRLLPLADIATPNRFELSWLTGVPLEDNKALMEAALD
EECCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHC
AGPAAMLVTSAFPFMNGSIGNILLTPTLALMAEHRRVDGPTNGLGDLTSAVFLARYLSGL
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
SEEKTLQSTTAAVFEIMARSAKRGADELMLEADASSLATPMAMVQTRRLLHPTKGLRT
CHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLPAPSDATTVIVISSHVVRGSVGNRAAVFALETLGFPVWAVPTVVLPWHPGHGVPGAP
CCCCCCCCEEEEEEECEEEECCCCCCEEEEEHHHHCCCHHHCCEEEEECCCCCCCCCCC
AGRIVPPADEFARLMQDLQRAPWLNEVGAVLTGYLGHPEQAAVVASLVKAVKANNPEAVY
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEE
LCDPVIGDEKGLYVPEATAMGIRDRLLPLADIATPNRFELSWLTGVPLEDNKALMEAALD
EECCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHC
AGPAAMLVTSAFPFMNGSIGNILLTPTLALMAEHRRVDGPTNGLGDLTSAVFLARYLSGL
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
SEEKTLQSTTAAVFEIMARSAKRGADELMLEADASSLATPMAMVQTRRLLHPTKGLRT
CHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]