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The map label for this gene is rsmB [H]

Identifier: 225853258

GI number: 225853258

Start: 1762179

End: 1763576

Strand: Direct

Name: rsmB [H]

Synonym: BMEA_A1864

Alternate gene names: 225853258

Gene position: 1762179-1763576 (Clockwise)

Preceding gene: 225853257

Following gene: 225853259

Centisome position: 82.9

GC content: 62.66

Gene sequence:

>1398_bases
GTGAACGATAAAAAACCCGCGCCGAAGCGTGGAAACAAAAAGCCGCAAACGAATAGCAACAGCGCCGCAGACCTGCGCCC
CGGTCTGGCGGCGCGTTTGTGTGCGGCCCGCCTTCTGGGCGCGGTGATCGAAAAGAACACCTCGCTCGACGGCCTGACCG
ACAATGCCCACGGCCATCCGCAATATCTGGCGCTGGAGCCGCGCGACCGCGCGCTGGTTCGCGCCATTCTGGGTTCTGCG
CTGCACAATCGCGGCAGCATCGAACGCGCCATCAACAAGCGGCTCGACCGGCCATTGCCGGAAAATGCCGTGGCGCTGAA
GCATCTGCTCCATGTTGCCGTCGCCCAGATTTTCTATCTCGACCTGCCCGACCATTCGGCAGTCGATCTTGCAGTCGAGG
CCGCGAACAGCGATCCGCGCAACCGCAAATATGCCGGTCTGGTCAACGCCCTGCTGCGGCGTCTCGCGCGCAACAAGGAA
CGCGCGCTCGCCCATACATTTGAGCCCGAAGCCAATGTGCCAGAATGGTTTGCCAAGAGCATCACCGACGCCTATGGCAC
GGAAAAAGCAGCGACCATTCTCGCCATGCACGCCTATGAGCCGCCGATCGATTTCACGGTCAAGGGCGATGCCAAGGCAT
GGGCCGAAAAGCTCGGCGGCGTGGCGCTGCCCAATGGTTCGGTGCGCCTGCAAACGGTGGAGGGCAATCTCACCGACCTG
CCCGGCTTTGCCGAGGGCGAATGGTGGGTGCAGGATGTAGCGGCAAGCCTGCCTGCGCGCCTGATGGACGATATCAAAGG
CAAACGGGTTGCCGATCTTTGTGCCGCCCCCGGCGGCAAGACGGCGCAGCTTGTGCTTCAGGGGGCCGACGTGACCGCGC
TTGACCTGTCCGAAAACCGGCTGAAGCGTCTCAACGCCAATCTGGAACGCCTCGGTTTCGAGGCGAAGACTGTCGCCACC
AATCTGATGGATTTTAAGCCCGACGAACTGTTCGACGCCGTGCTTCTGGATGCGCCCTGCTCGTCCACCGGCACGGTGCG
CCGTCACCCGGACGTGCCATGGACCAAGACGCCGCAGGACATTGCAAAACTCGCAGAACTTCAGGGCAAGCTTTTGGCGC
ACGCAGCCACGCTGGTGAAACCCGGCGGCGTGATCGTCTTTTCCAATTGCTCGCTGCATCCGCTCGAAGGCGAGGAAATG
GCGCGCAAGGCGCCGGAAAATCCGCTGCTGGAACCGTTCCCAATCACGGAGCAGGATTGTCCCGGCCTTGAAGGGCTGGT
GACGGCGGAAGGCTTCCTGCGCTCCACCCCGGCAGACCTGCCGCCGGATCGTTTGGACGGCAATCCGCACATGGCCGGCA
TGGACGGCTTCTTCGCGGCCCGTTTCAAGCGCGTATAA

Upstream 100 bases:

>100_bases
AAACAGTGGTCCCTGGGGGCAAAGAAGTGATAATGCAGGCGGCAACAGCAATGGCGGTTCCCGCTATCGGGGGCCGTGGT
CGTAAATAAAGAAGGCTAGT

Downstream 100 bases:

>100_bases
AACCGCAAAATGTGTATTTTGACATACTGGTCGCATTTCCGTCCGGTATGGTTAACGCTCGATTCACCATTTCCATACAA
TTGTATAAAGGAAACGGGCT

Product: Fmu domain-containing protein, Sun

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNDKKPAPKRGNKKPQTNSNSAADLRPGLAARLCAARLLGAVIEKNTSLDGLTDNAHGHPQYLALEPRDRALVRAILGSA
LHNRGSIERAINKRLDRPLPENAVALKHLLHVAVAQIFYLDLPDHSAVDLAVEAANSDPRNRKYAGLVNALLRRLARNKE
RALAHTFEPEANVPEWFAKSITDAYGTEKAATILAMHAYEPPIDFTVKGDAKAWAEKLGGVALPNGSVRLQTVEGNLTDL
PGFAEGEWWVQDVAASLPARLMDDIKGKRVADLCAAPGGKTAQLVLQGADVTALDLSENRLKRLNANLERLGFEAKTVAT
NLMDFKPDELFDAVLLDAPCSSTGTVRRHPDVPWTKTPQDIAKLAELQGKLLAHAATLVKPGGVIVFSNCSLHPLEGEEM
ARKAPENPLLEPFPITEQDCPGLEGLVTAEGFLRSTPADLPPDRLDGNPHMAGMDGFFAARFKRV

Sequences:

>Translated_465_residues
MNDKKPAPKRGNKKPQTNSNSAADLRPGLAARLCAARLLGAVIEKNTSLDGLTDNAHGHPQYLALEPRDRALVRAILGSA
LHNRGSIERAINKRLDRPLPENAVALKHLLHVAVAQIFYLDLPDHSAVDLAVEAANSDPRNRKYAGLVNALLRRLARNKE
RALAHTFEPEANVPEWFAKSITDAYGTEKAATILAMHAYEPPIDFTVKGDAKAWAEKLGGVALPNGSVRLQTVEGNLTDL
PGFAEGEWWVQDVAASLPARLMDDIKGKRVADLCAAPGGKTAQLVLQGADVTALDLSENRLKRLNANLERLGFEAKTVAT
NLMDFKPDELFDAVLLDAPCSSTGTVRRHPDVPWTKTPQDIAKLAELQGKLLAHAATLVKPGGVIVFSNCSLHPLEGEEM
ARKAPENPLLEPFPITEQDCPGLEGLVTAEGFLRSTPADLPPDRLDGNPHMAGMDGFFAARFKRV
>Mature_465_residues
MNDKKPAPKRGNKKPQTNSNSAADLRPGLAARLCAARLLGAVIEKNTSLDGLTDNAHGHPQYLALEPRDRALVRAILGSA
LHNRGSIERAINKRLDRPLPENAVALKHLLHVAVAQIFYLDLPDHSAVDLAVEAANSDPRNRKYAGLVNALLRRLARNKE
RALAHTFEPEANVPEWFAKSITDAYGTEKAATILAMHAYEPPIDFTVKGDAKAWAEKLGGVALPNGSVRLQTVEGNLTDL
PGFAEGEWWVQDVAASLPARLMDDIKGKRVADLCAAPGGKTAQLVLQGADVTALDLSENRLKRLNANLERLGFEAKTVAT
NLMDFKPDELFDAVLLDAPCSSTGTVRRHPDVPWTKTPQDIAKLAELQGKLLAHAATLVKPGGVIVFSNCSLHPLEGEEM
ARKAPENPLLEPFPITEQDCPGLEGLVTAEGFLRSTPADLPPDRLDGNPHMAGMDGFFAARFKRV

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=236, Percent_Identity=33.4745762711864, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI76150623, Length=236, Percent_Identity=33.4745762711864, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI32698918, Length=263, Percent_Identity=28.8973384030418, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI23199998, Length=250, Percent_Identity=30, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI270288818, Length=250, Percent_Identity=30, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI270288816, Length=251, Percent_Identity=30.2788844621514, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI8922322, Length=250, Percent_Identity=30, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI39995082, Length=170, Percent_Identity=31.1764705882353, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI301336155, Length=170, Percent_Identity=31.1764705882353, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI40316918, Length=177, Percent_Identity=32.7683615819209, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367212, Length=382, Percent_Identity=31.6753926701571, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI87081985, Length=233, Percent_Identity=32.618025751073, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536757, Length=240, Percent_Identity=30, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71998419, Length=243, Percent_Identity=28.8065843621399, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534021, Length=243, Percent_Identity=28.8065843621399, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=242, Percent_Identity=31.404958677686, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319447, Length=175, Percent_Identity=32, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI22024126, Length=241, Percent_Identity=31.9502074688797, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355201, Length=179, Percent_Identity=33.5195530726257, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920494, Length=208, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356513, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668781, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 50330; Mature: 50330

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKKPAPKRGNKKPQTNSNSAADLRPGLAARLCAARLLGAVIEKNTSLDGLTDNAHGHP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QYLALEPRDRALVRAILGSALHNRGSIERAINKRLDRPLPENAVALKHLLHVAVAQIFYL
CEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEE
DLPDHSAVDLAVEAANSDPRNRKYAGLVNALLRRLARNKERALAHTFEPEANVPEWFAKS
ECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHH
ITDAYGTEKAATILAMHAYEPPIDFTVKGDAKAWAEKLGGVALPNGSVRLQTVEGNLTDL
HHHHHCCHHHHHEEEEECCCCCCCEEECCCHHHHHHHHCCEECCCCCEEEEEECCCCCCC
PGFAEGEWWVQDVAASLPARLMDDIKGKRVADLCAAPGGKTAQLVLQGADVTALDLSENR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCHHH
LKRLNANLERLGFEAKTVATNLMDFKPDELFDAVLLDAPCSSTGTVRRHPDVPWTKTPQD
HHHHCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
IAKLAELQGKLLAHAATLVKPGGVIVFSNCSLHPLEGEEMARKAPENPLLEPFPITEQDC
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
PGLEGLVTAEGFLRSTPADLPPDRLDGNPHMAGMDGFFAARFKRV
CCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNDKKPAPKRGNKKPQTNSNSAADLRPGLAARLCAARLLGAVIEKNTSLDGLTDNAHGHP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QYLALEPRDRALVRAILGSALHNRGSIERAINKRLDRPLPENAVALKHLLHVAVAQIFYL
CEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEE
DLPDHSAVDLAVEAANSDPRNRKYAGLVNALLRRLARNKERALAHTFEPEANVPEWFAKS
ECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHH
ITDAYGTEKAATILAMHAYEPPIDFTVKGDAKAWAEKLGGVALPNGSVRLQTVEGNLTDL
HHHHHCCHHHHHEEEEECCCCCCCEEECCCHHHHHHHHCCEECCCCCEEEEEECCCCCCC
PGFAEGEWWVQDVAASLPARLMDDIKGKRVADLCAAPGGKTAQLVLQGADVTALDLSENR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCHHH
LKRLNANLERLGFEAKTVATNLMDFKPDELFDAVLLDAPCSSTGTVRRHPDVPWTKTPQD
HHHHCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
IAKLAELQGKLLAHAATLVKPGGVIVFSNCSLHPLEGEEMARKAPENPLLEPFPITEQDC
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
PGLEGLVTAEGFLRSTPADLPPDRLDGNPHMAGMDGFFAARFKRV
CCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]