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The map label for this gene is efp

Identifier: 225853165

GI number: 225853165

Start: 1671187

End: 1671747

Strand: Direct

Name: efp

Synonym: BMEA_A1762

Alternate gene names: 225853165

Gene position: 1671187-1671747 (Clockwise)

Preceding gene: 225853164

Following gene: 225853166

Centisome position: 78.62

GC content: 56.51

Gene sequence:

>561_bases
ATGAAGATCAATGGTAATGAAATCCGTCCCGGCAACGTCATCGAACACGAAGGCGGGCTTTGGGTTGCCGTGAAGACCAA
TGCCGTCAAGCCCGGCAAGGGCGGCGCCTATAATCAGGTCGAACTGAAAAACCTCATCAACGGCACCAAGCTCAACGAAC
GTTTCCGCGCAGCAGAAAGCGTCGAACGCGTACGCCTTGAGCAGAAGGATTTCTCGTTCCTCTATGAACAGGGCGAGGCG
CTGATTTTCATGGATACCGAAACCTACGAACAGCTCGAGCTCCAGAAGGATTTCGTCGGCGACCGCGCCGCCTTCCTTCA
GGACGGCATGATGGTGACGGTTGAACTTTACGAAGAAAAGCCAATCGGCATCCGCCTGCCCGATCAGGTAACGCTTGCGA
TCACCGAGGCCGATCCCGTCGTCAAGGGCCAGACCGCCGCTTCCTCCTACAAGCCGGCTGTGCTCGAAAACGGCATTCGC
ATCCCCGTTCCGCCGTTTATCGCCTCTGGTGAACGGGTGATCGTTGACACCAACGAACTGACTTATATCAGCCGCGCCTG
A

Upstream 100 bases:

>100_bases
CAAGGCACGTACGCAATCTCCGGGATGAAACCGGGTGGTTGCTTTTCGCCGTCATGCACCGGGTCGCACATAGTTTCCAC
ATTCATTTCGGATCAAGCTC

Downstream 100 bases:

>100_bases
TCAGTCCTCGACTGTTGCGGCGCCCGCCGGGGCGCCGCATGTCGCCCCTTGCGACCGTTCTTTCTCAGATCGCTCAATTC
CCGATTATCCGCCGACACAG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEA
LIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIR
IPVPPFIASGERVIVDTNELTYISRA

Sequences:

>Translated_186_residues
MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEA
LIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIR
IPVPPFIASGERVIVDTNELTYISRA
>Mature_186_residues
MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEA
LIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIR
IPVPPFIASGERVIVDTNELTYISRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=36.6666666666667, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=29.5698924731183, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_BRUA1 (B2S7E6)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935567.1
- ProteinModelPortal:   B2S7E6
- SMR:   B2S7E6
- GeneID:   6327557
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I16090
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20700; Mature: 20700

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAES
CCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHH
VERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEK
HHHHHHCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHCCEEEEEEEECCC
PIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFIASGERVIVDTNEL
CCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCE
TYISRA
EEEECC
>Mature Secondary Structure
MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAES
CCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHH
VERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEK
HHHHHHCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHCCEEEEEEEECCC
PIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFIASGERVIVDTNEL
CCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCE
TYISRA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA