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The map label for this gene is dhaK [H]

Identifier: 225853097

GI number: 225853097

Start: 1595650

End: 1596678

Strand: Reverse

Name: dhaK [H]

Synonym: BMEA_A1680

Alternate gene names: 225853097

Gene position: 1596678-1595650 (Counterclockwise)

Preceding gene: 225853098

Following gene: 225853096

Centisome position: 75.11

GC content: 56.75

Gene sequence:

>1029_bases
TTGAGCCCGCAGCTCATTCATATTACAGGAGATACCATGCAGCGTTTCATCAACAACCCGGACGAAGTCGTTGAGGATAC
CGTCAGGGGCTTTGTCAAAGCGCACTCCGATATCATTCGCCTTGCGGAAAATCCGCGCGTCATTGCCGCGAAAGATGCAC
CTGTCGCTGGCAAGGTTGGTGTTGTTACAGGCGGCGGATCCGGCCATGAACCAGCCTTCATCGGCTATACCGGCAAGAAT
ATGCTCGATGCGGTGGCAGTTGGTGAACTGTTTTCCTCCCCGACCGCTAAAAGCTTCCATGATGCCATACGCGAAGCAAA
TGGCGGCAAAGGCGTGGTGGTCCTCTATGGCAATTATGCCGGCGACAATATGAATGTGAAGATGGCGACCAAGCTGGCTG
CCAAGGATGGCATCGATGTTGCAACAGTCGTTGCAAATGACGATGTCTGTTCGGCCCCCGCCGCCGAACGCGAGAAGCGC
CGCGGCGTTGCCGGTGAGATATTCATGTGGAAGGTTGGCGGCGCAAAAGCGGCGACCGGAGCTACGCTTGAGGAGGTTCG
CGCAACGGCGCAGAAGGCCATCGATAATTGCCGTTCGATCGGCGTCGGGCTTGGACCGTGCACGTTGCCCGCCGTTGGCC
ATCCCAATTTTGAAATTGCGCCGGGCACGATGGAAGTCGGCATCGGCCATCATGGCGAGCCGGGCGTGCGGGTGGAGCCG
CTGAAGTCTGCGGCTGAGGTCGCAAGAGACATGTGCCAGATCGTGCTTGACGATCATGGACTGGCGGAAGGAACCGAAGT
TGCCGTTCTTGTCTCGGGTCTTGGCGCAACGCCACTCAACGAACTCTATATTCTTAACGACACGATCGAAACCGAAATTC
GGGCACGCGGGCTGAAGATCCATCGTACCTATATCGGCAACTATTTCACGTCGCTTGAAATGGTTGGGGCGACGCTGACG
GTCATGGCGCTGGACAGCGAGTTGAAGGAACTGCTCGATGTCGAAGTGCGCTGCACTACCATTTTGTGA

Upstream 100 bases:

>100_bases
ATCCCGAAGAGATTGCAGCCGCGGCCGTGTTCCTTGCTTCTGCTGGAGCCGACATGATTACGGGTGCCGATCTTCTGATC
GATGGCGGTTACACCATTCT

Downstream 100 bases:

>100_bases
GGAAGAGACCCGTGCAAACACTCAATAATGCAAAAGCTGGAGACATTGTGCTCACAATGGCCGAGAGGATTGTCGAGAAC
CGCGCCTATCTCAGCGAAAT

Product: glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSPQLIHITGDTMQRFINNPDEVVEDTVRGFVKAHSDIIRLAENPRVIAAKDAPVAGKVGVVTGGGSGHEPAFIGYTGKN
MLDAVAVGELFSSPTAKSFHDAIREANGGKGVVVLYGNYAGDNMNVKMATKLAAKDGIDVATVVANDDVCSAPAAEREKR
RGVAGEIFMWKVGGAKAATGATLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFEIAPGTMEVGIGHHGEPGVRVEP
LKSAAEVARDMCQIVLDDHGLAEGTEVAVLVSGLGATPLNELYILNDTIETEIRARGLKIHRTYIGNYFTSLEMVGATLT
VMALDSELKELLDVEVRCTTIL

Sequences:

>Translated_342_residues
MSPQLIHITGDTMQRFINNPDEVVEDTVRGFVKAHSDIIRLAENPRVIAAKDAPVAGKVGVVTGGGSGHEPAFIGYTGKN
MLDAVAVGELFSSPTAKSFHDAIREANGGKGVVVLYGNYAGDNMNVKMATKLAAKDGIDVATVVANDDVCSAPAAEREKR
RGVAGEIFMWKVGGAKAATGATLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFEIAPGTMEVGIGHHGEPGVRVEP
LKSAAEVARDMCQIVLDDHGLAEGTEVAVLVSGLGATPLNELYILNDTIETEIRARGLKIHRTYIGNYFTSLEMVGATLT
VMALDSELKELLDVEVRCTTIL
>Mature_341_residues
SPQLIHITGDTMQRFINNPDEVVEDTVRGFVKAHSDIIRLAENPRVIAAKDAPVAGKVGVVTGGGSGHEPAFIGYTGKNM
LDAVAVGELFSSPTAKSFHDAIREANGGKGVVVLYGNYAGDNMNVKMATKLAAKDGIDVATVVANDDVCSAPAAEREKRR
GVAGEIFMWKVGGAKAATGATLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFEIAPGTMEVGIGHHGEPGVRVEPL
KSAAEVARDMCQIVLDDHGLAEGTEVAVLVSGLGATPLNELYILNDTIETEIRARGLKIHRTYIGNYFTSLEMVGATLTV
MALDSELKELLDVEVRCTTIL

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of dhaR by binding to its sensor domain, in the

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=332, Percent_Identity=32.8313253012048, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI87081857, Length=349, Percent_Identity=36.676217765043, Blast_Score=229, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17565018, Length=320, Percent_Identity=30.625, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321055, Length=313, Percent_Identity=30.6709265175719, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6323570, Length=338, Percent_Identity=30.4733727810651, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 36013; Mature: 35881

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQLIHITGDTMQRFINNPDEVVEDTVRGFVKAHSDIIRLAENPRVIAAKDAPVAGKVG
CCCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
VVTGGGSGHEPAFIGYTGKNMLDAVAVGELFSSPTAKSFHDAIREANGGKGVVVLYGNYA
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GDNMNVKMATKLAAKDGIDVATVVANDDVCSAPAAEREKRRGVAGEIFMWKVGGAKAATG
CCCCEEEEEEHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCC
ATLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFEIAPGTMEVGIGHHGEPGVRVEP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCCEECC
LKSAAEVARDMCQIVLDDHGLAEGTEVAVLVSGLGATPLNELYILNDTIETEIRARGLKI
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHCCEEE
HRTYIGNYFTSLEMVGATLTVMALDSELKELLDVEVRCTTIL
EEEHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure 
SPQLIHITGDTMQRFINNPDEVVEDTVRGFVKAHSDIIRLAENPRVIAAKDAPVAGKVG
CCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
VVTGGGSGHEPAFIGYTGKNMLDAVAVGELFSSPTAKSFHDAIREANGGKGVVVLYGNYA
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GDNMNVKMATKLAAKDGIDVATVVANDDVCSAPAAEREKRRGVAGEIFMWKVGGAKAATG
CCCCEEEEEEHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCC
ATLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFEIAPGTMEVGIGHHGEPGVRVEP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCCEECC
LKSAAEVARDMCQIVLDDHGLAEGTEVAVLVSGLGATPLNELYILNDTIETEIRARGLKI
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHCCEEE
HRTYIGNYFTSLEMVGATLTVMALDSELKELLDVEVRCTTIL
EEEHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]