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The map label for this gene is ycbL [H]

Identifier: 225852994

GI number: 225852994

Start: 1490433

End: 1491089

Strand: Reverse

Name: ycbL [H]

Synonym: BMEA_A1568

Alternate gene names: 225852994

Gene position: 1491089-1490433 (Counterclockwise)

Preceding gene: 225852995

Following gene: 225852989

Centisome position: 70.15

GC content: 58.3

Gene sequence:

>657_bases
ATGAGGCAATTGCAGGCCATTATCGTTCCCGTCACGCCGTTTCAGCAAAATTGCACCATTCTCTTTGATGGTGAAACCAA
GAAGGGGGTGGTGATCGACCCCGGCGGCGACCTTGCGCGCATCAGGGAAGCCATTGAATCCCAGGGCATCGACGTCGAAG
CGATCTGGATCACGCATGGCCATATCGATCATGCCGCTGCCGCGCTCGATCTCAAGGAGGCGCTGGGTGTGGATATTATC
GGGCCGCACAGGGACGACAAGTTTCTCCTCGATAATCTCGTGGCGGCTGGCCTGAAATATGGAATTACCGAAGGTGTGCG
CAATGTCACGCCGGACCAATGGCTGGAGGAGGGGGACAAGGTTTGCGTTGCCGGGCATGTCTTCGACGTTTTCCATTGTC
CCGGTCATGCGCCGGGCCATGTCGTCTTTTTCAATCCTGAGGCGCGGTTTGCCATTGTCGGCGACGTGCTTTTCAACGGG
TCGGTCGGCCGCACGGATCTTCCGGGGGGTGATCACGCGACACTGATCCGCTCCATCAAGGAAAAGCTGCTGCCGCTTGG
TGACGATATCGGCTTCATCTGCGGGCATGGTCCCGGCGGACGGTTCGGGGAGGAACGGCGTTCCAATCCGTTTCTGACCG
ATACGGGATATGCCTGA

Upstream 100 bases:

>100_bases
CGGCCAATCGCCGTCCGTTTTTATTGTGCAAAGCCTTCACGCGAGCGGGGCTGACCATTATGTGTGAACAGGAACCCTAT
ACCGAGTTGGAGCAAAGAAC

Downstream 100 bases:

>100_bases
TTTGCAATGAAAAAAGCCGCCTTCAGGGGCGGCTTTTTGCTGGTTGATCGGTTCGGTGTCAGTTGGCCGTGCAGAAATGG
TCGCGACCGTCATAACCGCG

Product: beta-lactamase domain-containing protein

Products: glutathione; 2-hydroxy carboxylate

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRQLQAIIVPVTPFQQNCTILFDGETKKGVVIDPGGDLARIREAIESQGIDVEAIWITHGHIDHAAAALDLKEALGVDII
GPHRDDKFLLDNLVAAGLKYGITEGVRNVTPDQWLEEGDKVCVAGHVFDVFHCPGHAPGHVVFFNPEARFAIVGDVLFNG
SVGRTDLPGGDHATLIRSIKEKLLPLGDDIGFICGHGPGGRFGEERRSNPFLTDTGYA

Sequences:

>Translated_218_residues
MRQLQAIIVPVTPFQQNCTILFDGETKKGVVIDPGGDLARIREAIESQGIDVEAIWITHGHIDHAAAALDLKEALGVDII
GPHRDDKFLLDNLVAAGLKYGITEGVRNVTPDQWLEEGDKVCVAGHVFDVFHCPGHAPGHVVFFNPEARFAIVGDVLFNG
SVGRTDLPGGDHATLIRSIKEKLLPLGDDIGFICGHGPGGRFGEERRSNPFLTDTGYA
>Mature_218_residues
MRQLQAIIVPVTPFQQNCTILFDGETKKGVVIDPGGDLARIREAIESQGIDVEAIWITHGHIDHAAAALDLKEALGVDII
GPHRDDKFLLDNLVAAGLKYGITEGVRNVTPDQWLEEGDKVCVAGHVFDVFHCPGHAPGHVVFFNPEARFAIVGDVLFNG
SVGRTDLPGGDHATLIRSIKEKLLPLGDDIGFICGHGPGGRFGEERRSNPFLTDTGYA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=207, Percent_Identity=48.3091787439614, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: 3.1.2.6

Molecular weight: Translated: 23520; Mature: 23520

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQLQAIIVPVTPFQQNCTILFDGETKKGVVIDPGGDLARIREAIESQGIDVEAIWITHG
CCCCEEEEEECCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECC
HIDHAAAALDLKEALGVDIIGPHRDDKFLLDNLVAAGLKYGITEGVRNVTPDQWLEEGDK
CCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
VCVAGHVFDVFHCPGHAPGHVVFFNPEARFAIVGDVLFNGSVGRTDLPGGDHATLIRSIK
EEEEEEEEEEEECCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
EKLLPLGDDIGFICGHGPGGRFGEERRSNPFLTDTGYA
HHHCCCCCCCEEEEECCCCCCCCHHHCCCCCEECCCCC
>Mature Secondary Structure
MRQLQAIIVPVTPFQQNCTILFDGETKKGVVIDPGGDLARIREAIESQGIDVEAIWITHG
CCCCEEEEEECCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECC
HIDHAAAALDLKEALGVDIIGPHRDDKFLLDNLVAAGLKYGITEGVRNVTPDQWLEEGDK
CCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
VCVAGHVFDVFHCPGHAPGHVVFFNPEARFAIVGDVLFNGSVGRTDLPGGDHATLIRSIK
EEEEEEEEEEEECCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
EKLLPLGDDIGFICGHGPGGRFGEERRSNPFLTDTGYA
HHHCCCCCCCEEEEECCCCCCCCHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-(2-hydroxyacyl)glutathione; H2O

Specific reaction: S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]