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The map label for this gene is trkH [H]

Identifier: 225852979

GI number: 225852979

Start: 1475920

End: 1477320

Strand: Direct

Name: trkH [H]

Synonym: BMEA_A1551

Alternate gene names: 225852979

Gene position: 1475920-1477320 (Clockwise)

Preceding gene: 225852976

Following gene: 225852980

Centisome position: 69.43

GC content: 57.6

Gene sequence:

>1401_bases
ATGGCCGCGGCCATGCTTCTGCCCGCCGCAATCGATCTGCGTGACGGAAGCGACGACTGGTCGGTTTTCGTGCGCTCTTC
TGCCGCCACGGGTGCTCTTTCCGCGCTTATTTTTTTAGCGACACAGAACCAGACCATGCGTTTCACGCCGCGTCTGGGCT
TTCTTCTCACCGCCTGCCTCTGGCTGACGGCCGCGTTTCTGGGTTCCATACCGCTTTACTTTTCGCATCTGCCGATCAGC
TATGCGACCGCCTTCTTCGAGGCTATGTCGGGCGTAACCTCCACCGGAGCGACCGCGCTGACCGGCCTCGACAACATGCA
GCGCGGCATTCTTCTGTGGCGCTCGCTCCTGTGCTGGATCGGGGGCGTCGGCTTCATCGGCCTTGCGCTTTTGATGCTGC
CCTCCTTGCGGGCAGGCGGCCTTGCGCTTTTTCACATGGAAAATTCCGACAAATCGGAAAAAATCCTGCCGCGCATGAAC
CAGATCGCGCTCGGCATCATGGCCGCATATCTAAGCCTCACGGCTGCCTGCACGGTTGCCTATTTCGCTGTGGGCATGAG
CGTTTTCGACGCCATCAACCACAGTCTCACCACCATTGCCACTGCGGGCTTTTCCACCCATGACAGTTCGATCGGCTTTT
ATCAGGGCAACCGGATGCTGCTCGTCGTATCCACCATATTCATGGCGCTCTCAGCCCTCCCCTTCGTGCTTTACATCAAG
GCTTTCATGCCGCAGCGCATGGAATTGCTCACCGACCCGCAGGTGAAACTCTTCTTCACCATCATCATCGCCTTCAGCTT
CATCCTCGCCATCGTCCTGCGCCTCAGCACCAATATACCTTTCGGCGATGCCCTGATCTCGGCCTCGTTCCATTTTGTCT
CGGTGATAACGACGACCGGATATGCAACCGAGGATTATTCCCTCTGGGGACCGCCAGCGATTGGAATTTTCTTTCTCGCC
TCCTTCCTCGGCGGCTGTGCAGGCTCGACTTCCGGCGGCATCAAAATGAACCGCCTCATCATCCTGTGGAGCCTGACGCA
GGCCAATCTTGCGCGCCTCATCATGCCGCATGCCGTCATCAAGATTCGCTACGGCTCATCGGAAGTTTCGGGCGATATCG
CGCAGAATGTATTGCTTTACCTGTTTCTTTACAGCGCCTCGCTCATTATCGGCGCGGTGCTGCTCGCATCCTTCGGCCTT
GATTTCGTATCCGCCTTCACGGGTTCGCTGACGGCATTATCGAATGTCGGTCCCGGCCTTGGCGACAAGATCGGCCCCGC
TGGCAATTTCTCCACCGTTCGCGATCAGGCGCTTTGGGTGCTCTCATTCCTTATGCTGGCAGGCCGACTGGAACTCGTCA
CCATATTCATCCTCTTCACACGCTCATTCTGGGTGCGTTGA

Upstream 100 bases:

>100_bases
ACGCTAAACAGGCAATGCATAAGGCCTAATTCGTTCAGTTCCGGAGCCGTCCACCATTTACAAGACAGTCGCCAATATCT
GCGCGCGCTTCGGCCTTATT

Downstream 100 bases:

>100_bases
TACAGTATGGCAGGCTTGCTGAATACGGTTCATGGAGGCCGCAACCGGCACGCAGCCGACACACCGTTCCGCGTTCAATC
TGTACCGACAAACGTGCAAG

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MAAAMLLPAAIDLRDGSDDWSVFVRSSAATGALSALIFLATQNQTMRFTPRLGFLLTACLWLTAAFLGSIPLYFSHLPIS
YATAFFEAMSGVTSTGATALTGLDNMQRGILLWRSLLCWIGGVGFIGLALLMLPSLRAGGLALFHMENSDKSEKILPRMN
QIALGIMAAYLSLTAACTVAYFAVGMSVFDAINHSLTTIATAGFSTHDSSIGFYQGNRMLLVVSTIFMALSALPFVLYIK
AFMPQRMELLTDPQVKLFFTIIIAFSFILAIVLRLSTNIPFGDALISASFHFVSVITTTGYATEDYSLWGPPAIGIFFLA
SFLGGCAGSTSGGIKMNRLIILWSLTQANLARLIMPHAVIKIRYGSSEVSGDIAQNVLLYLFLYSASLIIGAVLLASFGL
DFVSAFTGSLTALSNVGPGLGDKIGPAGNFSTVRDQALWVLSFLMLAGRLELVTIFILFTRSFWVR

Sequences:

>Translated_466_residues
MAAAMLLPAAIDLRDGSDDWSVFVRSSAATGALSALIFLATQNQTMRFTPRLGFLLTACLWLTAAFLGSIPLYFSHLPIS
YATAFFEAMSGVTSTGATALTGLDNMQRGILLWRSLLCWIGGVGFIGLALLMLPSLRAGGLALFHMENSDKSEKILPRMN
QIALGIMAAYLSLTAACTVAYFAVGMSVFDAINHSLTTIATAGFSTHDSSIGFYQGNRMLLVVSTIFMALSALPFVLYIK
AFMPQRMELLTDPQVKLFFTIIIAFSFILAIVLRLSTNIPFGDALISASFHFVSVITTTGYATEDYSLWGPPAIGIFFLA
SFLGGCAGSTSGGIKMNRLIILWSLTQANLARLIMPHAVIKIRYGSSEVSGDIAQNVLLYLFLYSASLIIGAVLLASFGL
DFVSAFTGSLTALSNVGPGLGDKIGPAGNFSTVRDQALWVLSFLMLAGRLELVTIFILFTRSFWVR
>Mature_465_residues
AAAMLLPAAIDLRDGSDDWSVFVRSSAATGALSALIFLATQNQTMRFTPRLGFLLTACLWLTAAFLGSIPLYFSHLPISY
ATAFFEAMSGVTSTGATALTGLDNMQRGILLWRSLLCWIGGVGFIGLALLMLPSLRAGGLALFHMENSDKSEKILPRMNQ
IALGIMAAYLSLTAACTVAYFAVGMSVFDAINHSLTTIATAGFSTHDSSIGFYQGNRMLLVVSTIFMALSALPFVLYIKA
FMPQRMELLTDPQVKLFFTIIIAFSFILAIVLRLSTNIPFGDALISASFHFVSVITTTGYATEDYSLWGPPAIGIFFLAS
FLGGCAGSTSGGIKMNRLIILWSLTQANLARLIMPHAVIKIRYGSSEVSGDIAQNVLLYLFLYSASLIIGAVLLASFGLD
FVSAFTGSLTALSNVGPGLGDKIGPAGNFSTVRDQALWVLSFLMLAGRLELVTIFILFTRSFWVR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=428, Percent_Identity=31.5420560747664, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI48994987, Length=473, Percent_Identity=34.2494714587738, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 50131; Mature: 49999

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00539 PYROKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAMLLPAAIDLRDGSDDWSVFVRSSAATGALSALIFLATQNQTMRFTPRLGFLLTACL
CCCHHHCCHHEECCCCCCCCEEEEECCCHHHHHHHHHHEEECCCCEEECCHHHHHHHHHH
WLTAAFLGSIPLYFSHLPISYATAFFEAMSGVTSTGATALTGLDNMQRGILLWRSLLCWI
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHH
GGVGFIGLALLMLPSLRAGGLALFHMENSDKSEKILPRMNQIALGIMAAYLSLTAACTVA
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFAVGMSVFDAINHSLTTIATAGFSTHDSSIGFYQGNRMLLVVSTIFMALSALPFVLYIK
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHH
AFMPQRMELLTDPQVKLFFTIIIAFSFILAIVLRLSTNIPFGDALISASFHFVSVITTTG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEECC
YATEDYSLWGPPAIGIFFLASFLGGCAGSTSGGIKMNRLIILWSLTQANLARLIMPHAVI
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCEEE
KIRYGSSEVSGDIAQNVLLYLFLYSASLIIGAVLLASFGLDFVSAFTGSLTALSNVGPGL
EEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDKIGPAGNFSTVRDQALWVLSFLMLAGRLELVTIFILFTRSFWVR
CCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAAMLLPAAIDLRDGSDDWSVFVRSSAATGALSALIFLATQNQTMRFTPRLGFLLTACL
CCHHHCCHHEECCCCCCCCEEEEECCCHHHHHHHHHHEEECCCCEEECCHHHHHHHHHH
WLTAAFLGSIPLYFSHLPISYATAFFEAMSGVTSTGATALTGLDNMQRGILLWRSLLCWI
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHH
GGVGFIGLALLMLPSLRAGGLALFHMENSDKSEKILPRMNQIALGIMAAYLSLTAACTVA
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFAVGMSVFDAINHSLTTIATAGFSTHDSSIGFYQGNRMLLVVSTIFMALSALPFVLYIK
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHH
AFMPQRMELLTDPQVKLFFTIIIAFSFILAIVLRLSTNIPFGDALISASFHFVSVITTTG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEECC
YATEDYSLWGPPAIGIFFLASFLGGCAGSTSGGIKMNRLIILWSLTQANLARLIMPHAVI
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCEEE
KIRYGSSEVSGDIAQNVLLYLFLYSASLIIGAVLLASFGLDFVSAFTGSLTALSNVGPGL
EEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDKIGPAGNFSTVRDQALWVLSFLMLAGRLELVTIFILFTRSFWVR
CCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]