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The map label for this gene is carA

Identifier: 225852965

GI number: 225852965

Start: 1459788

End: 1461011

Strand: Direct

Name: carA

Synonym: BMEA_A1536

Alternate gene names: 225852965

Gene position: 1459788-1461011 (Clockwise)

Preceding gene: 225852963

Following gene: 225852968

Centisome position: 68.67

GC content: 60.54

Gene sequence:

>1224_bases
ATGACTGAAACGACCCCGAAAACAGCACCCTGGACCGTTCAGAAGCGAACCGCCGTTCTCGTCCTCGCCGATGGAACCGT
GATCGAAGGCAAGGGCCTGGGCGCGACCGGCGCGGTTGAGGCCGAAGTCGTCTTCAACACCGCTCTCACCGGCTATGAGG
AAATACTGACCGACCCGTCCTATGCCGGACAGATCGTCACCTTCACTTTCCCACATATCGGCAATGTCGGCGCCAATGCC
GAAGATATCGAAGATCTGACACCCGCCAACCGCCACGGCGCAGTCGGCGCGATCTTCAAGGCAGACATCACCGCACCCTC
GAATTTCCGTGCCGCAAAAGACCTCGATAGCTGGCTCAAGCATCGCGGAATCATTGCGCTTGCCGGCATCGACACCCGCG
CCCTCACCGCCCTCATCCGCGAGCGTGGCGCGCAAAACGCCGTTATCGCGCATGACCCGAACGGAAATTTCGATCTCGAC
GCCCTGAAAGCGCGCGCCGCCAACTGGTGCGGCCTTGAAAATCTCGATCTCGCCAAGGATGTCACCATCGGCCAGAGCCT
CGTCTGGAAGGAACTGCCATGGACACTCCAGGACGGCTATGGCGAACAGGACGCACCGCAATATCACGTCGTCGCTCTCG
ATTTCGGTGTGAAGCGCAATATTCTGCGCCTTCTGACCGGGCTTGGCGCAAAGGTCACGGTTTTACCGGCCACGGCAACA
GCCGAAGACGTTCTGGCGCATAATCCCGATGGCGTTTTCCTGTCCAATGGTCCCGGCGATCCGGCGGCAACGGGCGAATA
TGCCGTGCCGACCATCGGCAAGCTGGTGGAAACCGGCATTCCCCTTTTCGGCATCTGCCTCGGCCACCAGATGCTGGCGC
TGGCGCTCGGCGGACGCACGGAAAAGATGCATCAGGGCCATCACGGTGCAAACCACCCGGTGAAGGATTATACGACCGGC
AAGGTGGAAATCGTCTCGATGAATCACGGTTTCGCAGTTGATTCGGACTCGCTGCCGGAAAATGTCGAGGAAACCCATGT
GTCGCTCTTCGACGGCACCAATTGCGGCCTGCGTGTCGTCGGCAAGCCAGTCTTCTCCGTGCAGCATCACCCGGAAGCCT
CCCCCGGCCCGCAGGATTCGCACTATCTGTTCCGCCGGTTCATCAATCTCATCCGCGAGAGGAAAGGCCAGGCTCCTCTG
CCGGAGCGCGAACAGGCTGCCTGA

Upstream 100 bases:

>100_bases
CACCTCCCCGGCGGTGGGTTGAAACACGGTCGCGTGCCGCATAACTGGTAATGAAATGACAGCACAGGCTGGCGATGCCA
ACGAAACAGGAGTGCACACT

Downstream 100 bases:

>100_bases
ACGGCAATTGAAATTTTCGCAAAGGAAAAGGCGGTCACAAGCCGCCTTTTTCTATAGTCTGGAAGCGATTTTAGAGCGCA
TCCTGAAAAGTGTGAAACGG

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANA
EDIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLD
ALKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATAT
AEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTG
KVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPL
PEREQAA

Sequences:

>Translated_407_residues
MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANA
EDIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLD
ALKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATAT
AEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTG
KVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPL
PEREQAA
>Mature_406_residues
TETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANAE
DIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDA
LKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATATA
EDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTGK
VEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLP
EREQAA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Homo sapiens, GI18105007, Length=383, Percent_Identity=36.8146214099217, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI21361331, Length=400, Percent_Identity=35, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI169790915, Length=398, Percent_Identity=34.6733668341709, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1786215, Length=386, Percent_Identity=53.3678756476684, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI193204318, Length=399, Percent_Identity=36.5914786967419, Blast_Score=224, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6324878, Length=394, Percent_Identity=36.5482233502538, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6322331, Length=416, Percent_Identity=33.8942307692308, Blast_Score=222, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=30.3664921465969, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45555749, Length=402, Percent_Identity=36.5671641791045, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24642586, Length=402, Percent_Identity=36.0696517412935, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CARA_BRUA1 (B2S6U9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935370.1
- ProteinModelPortal:   B2S6U9
- SMR:   B2S6U9
- GeneID:   6327349
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I14030
- HOGENOM:   HBG286341
- OMA:   FTYPELG
- ProtClustDB:   PRK12564
- HAMAP:   MF_01209_B
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- PANTHER:   PTHR11405:SF4
- PRINTS:   PR00097
- PRINTS:   PR00099
- PRINTS:   PR00096
- TIGRFAMs:   TIGR01368

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase; SSF52021 CP_synthsmall

EC number: =6.3.5.5

Molecular weight: Translated: 43537; Mature: 43405

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 286-286 ACT_SITE 370-370 ACT_SITE 372-372

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPS
CCCCCCCCCCEEEECCEEEEEEECCEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHCCCC
YAGQIVTFTFPHIGNVGANAEDIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLK
CCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHH
HRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDALKARAANWCGLENLDLAKD
HCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHC
VTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATAT
CCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCC
AEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRT
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
EKMHQGHHGANHPVKDYTTGKVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVV
HHHHCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHEEEEECCCCCCEEEE
GKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLPEREQAA
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure 
TETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPS
CCCCCCCCCEEEECCEEEEEEECCEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHCCCC
YAGQIVTFTFPHIGNVGANAEDIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLK
CCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHH
HRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDALKARAANWCGLENLDLAKD
HCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHC
VTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATAT
CCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCC
AEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRT
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
EKMHQGHHGANHPVKDYTTGKVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVV
HHHHCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHEEEEECCCCCCEEEE
GKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLPEREQAA
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA