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The map label for this gene is serB [C]

Identifier: 225852874

GI number: 225852874

Start: 1366300

End: 1367199

Strand: Direct

Name: serB [C]

Synonym: BMEA_A1438

Alternate gene names: 225852874

Gene position: 1366300-1367199 (Clockwise)

Preceding gene: 225852869

Following gene: 225852885

Centisome position: 64.28

GC content: 60.56

Gene sequence:

>900_bases
ATGTCGCAGCAGGTTTCTCTCGTCGCTACCCTGATCGCCAACCCGGCAAAAGCCGCGCTTGCCCCTTCGCTCGGCATTAA
AGCCTCGGCGGCAGTGAATGCAACCGGACTTTACTGGCTGGCAGATGATATTGCCTGCGACATTCCCCTTCCCCTTGGCA
TGGAGGCAAGTGAGGCGGATGCATCATTGCGCGCCACCCTTGACGGCGCGCCTATCGACGTGGTGGTGCAGGAACAGGAA
CGCCGGCGCAAGAAAATTTTGATTGCCGATATGGATTCCACCATGATCGGGCAGGAATGTATCGATGAACTGGCGGAAGA
AGCGGGCCTGCGCGACCATGTGGCCGCGATCACCGCGCGCGCAATGAATGGCGAGATTGCCTTCGAGCCGGCACTTCGCG
AGCGCGTCGCGCTTTTGAAGGGATTGCCGCTTTCGGTGATCGACAAGGTTATCTCCACCCGCATCACCCTCACCCCCGGC
GGGCCGCAACTGGTGCGCACCATGCGCAAGCACGGCGCTTATACAGCACTCGTTTCCGGCGGCTTCACCTCGTTTACCCG
CCGCATTGCCGAAATGATCGGCTTCAATGAGGAACGCGCCAATCGCCTGATCGATGACGGAACCCGCCTGACGGGTACCG
TCGCTGAGCCTATATTAGGCCGCGAAGCCAAGGTCGAAAAACTGGTCGAGATCGCCGAACGCCTTGGCCTCACCCCCGAA
GACGCTATCGCAGTCGGCGATGGCGCGAACGATCTGGGCATGATCCAGCTTGCCGGGACCGGCGTGGCGCTTCACGCCAA
GCCCGCCGTGGCCGCACAGGCAAAAATGCGCATCGACCATGGCGACCTCACCGCCCTTCTCTATATCCAGGGCTACCGAA
AGGCAGATTTCGTCCAATAA

Upstream 100 bases:

>100_bases
GCCATGCGAATGGCAAGTGCCGACTTGCCGCTGGCCGTTGGGCCAGCTATCAGGATCGCATTCTTGACTGCATCCTCACT
CATCGTCGGAATTGCTCTCC

Downstream 100 bases:

>100_bases
GCCTTCCCGATTGCCCATTGCCCGCCCGTCTTCGGCGCATTCAGGCGGCCTGACCGGCCACCCAGCCCGAAGACCAGGCC
CATTGGAAATTATAGCCGCC

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEADASLRATLDGAPIDVVVQEQE
RRRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITARAMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPG
GPQLVRTMRKHGAYTALVSGGFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERLGLTPE
DAIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ

Sequences:

>Translated_299_residues
MSQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEADASLRATLDGAPIDVVVQEQE
RRRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITARAMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPG
GPQLVRTMRKHGAYTALVSGGFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERLGLTPE
DAIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ
>Mature_298_residues
SQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEADASLRATLDGAPIDVVVQEQER
RRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITARAMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPGG
PQLVRTMRKHGAYTALVSGGFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERLGLTPED
AIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=169, Percent_Identity=34.3195266272189, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790849, Length=226, Percent_Identity=40.2654867256637, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI115534454, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534456, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=224, Percent_Identity=37.9464285714286, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24661601, Length=177, Percent_Identity=29.3785310734463, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31785; Mature: 31654

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEAD
CCCHHHHHHHHHCCCHHHHHCCCCCCCCCCEECCCEEEEEECCEEECCCCCCCCCCCCCC
ASLRATLDGAPIDVVVQEQERRRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITAR
CEEEEEECCCCEEEEECCHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPGGPQLVRTMRKHGAYTALVSG
HCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCHHHHHHHHHCCCEEEEECC
GFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERLGLTPE
CHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCC
DAIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ
CCEEECCCCCCCEEEEEECCCEEEECCCCHHHHHHEEECCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEAD
CCHHHHHHHHHCCCHHHHHCCCCCCCCCCEECCCEEEEEECCEEECCCCCCCCCCCCCC
ASLRATLDGAPIDVVVQEQERRRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITAR
CEEEEEECCCCEEEEECCHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPGGPQLVRTMRKHGAYTALVSG
HCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCHHHHHHHHHCCCEEEEECC
GFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERLGLTPE
CHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCC
DAIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ
CCEEECCCCCCCEEEEEECCCEEEECCCCHHHHHHEEECCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]