Click here to switch to the map view.

The map label for this gene is ycjS [C]

Identifier: 225852828

GI number: 225852828

Start: 1323455

End: 1324570

Strand: Direct

Name: ycjS [C]

Synonym: BMEA_A1390

Alternate gene names: 225852828

Gene position: 1323455-1324570 (Clockwise)

Preceding gene: 225852822

Following gene: 225852836

Centisome position: 62.26

GC content: 57.26

Gene sequence:

>1116_bases
ATGGCTGTTATAGCAGGCTTGATCGGTTCCGGCTTCATGGGCAAAACCCACGCGCTGGCGCTTGCCAATGTCAATCGCAT
CTTCGACCTGCCGCTTGCGGTGCAGCTTCACACGCTTGGCGATATTGACGTGCAAATAGCCCGCAAAGCCGCGCGGCAAC
TGGGCTTTGCCCATGCCACTGGCGACTGGCGTGACCTCATTTCCAATCCCGACATCAACCTCATCGATATCACCACCCCC
AACCGCTTCCATAAGGAAATGGCTCTGGCGGCCATCAAGGCCGGAAAGCATGTCTATTGTGAAAAGCCGCTGGCGCCCTC
TGCCGCCGATTGCCTGGAAATGACGCTGGCCGCAGAACGCGAGGGTATCCAGACGGCTGTGGATTTCAACTATCTGAAAA
ACCCCATGATGAAGCTTGCACAAGAGATTATCGCAAGCGGTGAACTGGGTGAAATCCGAAATTTTCGCGGCATTCACGCC
GAAGATTTCATGGCCGACGCCCGCATTCCGTGGACATGGCGGCTTGATCCGGCAGGTGGCGGTGGAGCACTTGCCGATAT
CGGCAGTCACATCATCGCAACCGCGCGCTATCTGATCGGCCCAATCGCGGACGTGATGGGCGAGGCCGTTACGCTCATTC
GTGAGCGCCCCGACATGGCTGATCTCTCCCGCACGAAACCCGTGGAAGTGGATGATGTCTGCCACGCTTTCATGCGTTTT
GAAAACGGCGCAACCGGCACACTGGAAGCAAGCTGGGTGGCAAGCGGGCGCAAGATGCAGCACGATTTCGAGATTTCAGG
ATCGAAAGGCGCCATCTTCTTCTCGCAGGAGCGTTTCAATGAACTGGAATTGTTCCTCTATTCCGACCGCAAGGGGCAGC
AGGGTTTCCGCAAGATTTTTGCCGGGCCGGAACATGAGCCCTATGGCGCTTTCTGCGTGGCGGGCGGCCATCAGATCGGC
TTCAACGACCTCAAGACCATCGAAGTGCGCGATTTCGTGCTGGCCATTGCCGGGCAGAAAACCGGCCATGCCGATTTCCG
CGAAGGCTATGAGGTTCAAAAGACGGTGGAGACGATCTATGCCTCGTCCCGCGAGCGCCAGTGGAAGAAAATCTAG

Upstream 100 bases:

>100_bases
CTGATCCCGCTCGATGTGTGAGGCAAATGCGACAAAACACATAGCCAATCACCATCAGAGAGCTGGAGATGATTGACTTA
CGGCTTGGGAGGGGATGGAA

Downstream 100 bases:

>100_bases
CGAGGTTGTAGTGCGGTCGGATGGACGATGAATTCGCCATCCACCATCATGATCCGCGCACGGATCCCATAGACATCGCG
CAGGCGTTGCGGGGTGAAGA

Product: 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase

Products: 2,4,6/3,5-pentahydroxycyclohexanone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MAVIAGLIGSGFMGKTHALALANVNRIFDLPLAVQLHTLGDIDVQIARKAARQLGFAHATGDWRDLISNPDINLIDITTP
NRFHKEMALAAIKAGKHVYCEKPLAPSAADCLEMTLAAEREGIQTAVDFNYLKNPMMKLAQEIIASGELGEIRNFRGIHA
EDFMADARIPWTWRLDPAGGGGALADIGSHIIATARYLIGPIADVMGEAVTLIRERPDMADLSRTKPVEVDDVCHAFMRF
ENGATGTLEASWVASGRKMQHDFEISGSKGAIFFSQERFNELELFLYSDRKGQQGFRKIFAGPEHEPYGAFCVAGGHQIG
FNDLKTIEVRDFVLAIAGQKTGHADFREGYEVQKTVETIYASSRERQWKKI

Sequences:

>Translated_371_residues
MAVIAGLIGSGFMGKTHALALANVNRIFDLPLAVQLHTLGDIDVQIARKAARQLGFAHATGDWRDLISNPDINLIDITTP
NRFHKEMALAAIKAGKHVYCEKPLAPSAADCLEMTLAAEREGIQTAVDFNYLKNPMMKLAQEIIASGELGEIRNFRGIHA
EDFMADARIPWTWRLDPAGGGGALADIGSHIIATARYLIGPIADVMGEAVTLIRERPDMADLSRTKPVEVDDVCHAFMRF
ENGATGTLEASWVASGRKMQHDFEISGSKGAIFFSQERFNELELFLYSDRKGQQGFRKIFAGPEHEPYGAFCVAGGHQIG
FNDLKTIEVRDFVLAIAGQKTGHADFREGYEVQKTVETIYASSRERQWKKI
>Mature_370_residues
AVIAGLIGSGFMGKTHALALANVNRIFDLPLAVQLHTLGDIDVQIARKAARQLGFAHATGDWRDLISNPDINLIDITTPN
RFHKEMALAAIKAGKHVYCEKPLAPSAADCLEMTLAAEREGIQTAVDFNYLKNPMMKLAQEIIASGELGEIRNFRGIHAE
DFMADARIPWTWRLDPAGGGGALADIGSHIIATARYLIGPIADVMGEAVTLIRERPDMADLSRTKPVEVDDVCHAFMRFE
NGATGTLEASWVASGRKMQHDFEISGSKGAIFFSQERFNELELFLYSDRKGQQGFRKIFAGPEHEPYGAFCVAGGHQIGF
NDLKTIEVRDFVLAIAGQKTGHADFREGYEVQKTVETIYASSRERQWKKI

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=294, Percent_Identity=22.108843537415, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787574, Length=369, Percent_Identity=24.9322493224932, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082405, Length=211, Percent_Identity=28.436018957346, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081947, Length=284, Percent_Identity=26.056338028169, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323975, Length=185, Percent_Identity=29.1891891891892, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581117, Length=273, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.1.1.18

Molecular weight: Translated: 40890; Mature: 40759

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIAGLIGSGFMGKTHALALANVNRIFDLPLAVQLHTLGDIDVQIARKAARQLGFAHAT
CCEEEEHHCCCCCCCHHEEEECCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
GDWRDLISNPDINLIDITTPNRFHKEMALAAIKAGKHVYCEKPLAPSAADCLEMTLAAER
CCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHH
EGIQTAVDFNYLKNPMMKLAQEIIASGELGEIRNFRGIHAEDFMADARIPWTWRLDPAGG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHCCCCCEEEEECCCCC
GGALADIGSHIIATARYLIGPIADVMGEAVTLIRERPDMADLSRTKPVEVDDVCHAFMRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHH
ENGATGTLEASWVASGRKMQHDFEISGSKGAIFFSQERFNELELFLYSDRKGQQGFRKIF
CCCCCCEEEEHHHHCCCCCCCCEEECCCCCEEEEEHHCCCEEEEEEEECCCCHHHHHHHH
AGPEHEPYGAFCVAGGHQIGFNDLKTIEVRDFVLAIAGQKTGHADFREGYEVQKTVETIY
CCCCCCCCCEEEEECCCEECCCCCEEEEHHHEEEEEECCCCCCCHHHHCHHHHHHHHHHH
ASSRERQWKKI
HHHHHHHHCCC
>Mature Secondary Structure 
AVIAGLIGSGFMGKTHALALANVNRIFDLPLAVQLHTLGDIDVQIARKAARQLGFAHAT
CEEEEHHCCCCCCCHHEEEECCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
GDWRDLISNPDINLIDITTPNRFHKEMALAAIKAGKHVYCEKPLAPSAADCLEMTLAAER
CCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHH
EGIQTAVDFNYLKNPMMKLAQEIIASGELGEIRNFRGIHAEDFMADARIPWTWRLDPAGG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHCCCCCEEEEECCCCC
GGALADIGSHIIATARYLIGPIADVMGEAVTLIRERPDMADLSRTKPVEVDDVCHAFMRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHH
ENGATGTLEASWVASGRKMQHDFEISGSKGAIFFSQERFNELELFLYSDRKGQQGFRKIF
CCCCCCEEEEHHHHCCCCCCCCEEECCCCCEEEEEHHCCCEEEEEEEECCCCHHHHHHHH
AGPEHEPYGAFCVAGGHQIGFNDLKTIEVRDFVLAIAGQKTGHADFREGYEVQKTVETIY
CCCCCCCCCEEEEECCCEECCCCCEEEEHHHEEEEEECCCCCCCHHHHCHHHHHHHHHHH
ASSRERQWKKI
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: myo-inositol; NAD+

Specific reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]