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The map label for this gene is rpoC [H]

Identifier: 225852738

GI number: 225852738

Start: 1225798

End: 1230000

Strand: Reverse

Name: rpoC [H]

Synonym: BMEA_A1286

Alternate gene names: 225852738

Gene position: 1230000-1225798 (Counterclockwise)

Preceding gene: 225852739

Following gene: 225852736

Centisome position: 57.86

GC content: 58.05

Gene sequence:

>4203_bases
ATGAACCAAGAGGTCATGAATCTTTTCAATCCTCAGGCTCCGGCGCAAACGTTCGATTCCATCAGAATCTCGATCGCCAG
CCCTGAGAAGATTCTGTCCTGGTCATACGGCGAGATCAAGAAGCCGGAGACGATCAACTACCGTACGTTCAAGCCAGAAC
GCGATGGTCTCTTCTGCGCGCGCATCTTCGGCCCGATCAAGGACTATGAATGCTTGTGCGGCAAGTACAAGCGTATGAAA
TACAAGGGCATCATCTGCGAAAAATGCGGCGTGGAAGTCACGCTTTCCCGCGTTCGCCGCGAGCGCATGGGCCATATCGA
ACTTGCAGCACCGGTTGCGCATATCTGGTTCCTGAAGTCGCTGCCAAGCCGCATCGGCACGCTTCTGGACATGACGCTCA
AGGATATCGAGCGCGTCCTGTACTTTGAAAACTACATCGTCACCGAACCCGGCCTGACCTCGCTGAAGGAGCACCAGCTT
CTGTCAGAAGAGGAATATATGATCGCCGTCGATGAATTCGGCGAAGATCAGTTCACGGCGCTCATCGGGGCGGAAGCGAT
CTACGAACTGCTGGCTTCGATGGAACTTGAAAAGATCGCTGCGGACCTGCGCGTCGATCTGGCCGAGACCACTTCGGACC
TGAAGCAGAAGAAGCTGATGAAGCGTCTGAAGATCGTCGAGAACTTCCTGGAGTCGGGAAACCGCCCGGAATGGATGATC
ATGAAGATCGTTCCGGTGATCCCGCCGGATCTGCGCCCGCTCGTGCCGCTGGATGGCGGTCGTTTTGCGACGTCGGATCT
CAACGATCTCTATCGCCGCGTCATCAACCGTAACAACCGTCTGAAGCGCCTGATCGAACTGCGCGCGCCGGGCATCATCA
TCCGCAACGAAAAGCGCATGTTGCAGGAAGCTGTCGATGCGCTGTTCGACAACGGCCGTCGCGGCCGCGTCATCACCGGT
GCCAACAAGCGCCCGCTGAAGTCGCTGTCCGACATGCTCAAGGGCAAGCAGGGCCGCTTCCGTCAGAACCTGCTCGGCAA
GCGCGTGGACTATTCAGGCCGTTCGGTCATCGTGACCGGCCCGGAACTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGA
TGGCGCTCGAACTGTTCAAGCCGTTCATCTATGCGCGTCTTGACGCCAAGGGCTATTCGTCCACCGTCAAGCAGGCGAAG
AAGCTGGTTGAAAAGGAACGCCCGGAAGTCTGGGATATCCTTGACGAAGTGATCCGCGAGCATCCGGTTCTTCTGAACCG
TGCCCCGACGCTGCACCGTCTCGGCATCCAGGCGTTTGAACCGACCCTGATCGAAGGCAAGGCCATTCAGCTTCATCCGC
TCGTCTGCACGGCGTTCAATGCCGACTTCGACGGCGACCAGATGGCTGTTCACGTTCCGCTTTCGCTTGAAGCCCAGCTT
GAAGCGCGCGTGCTGATGATGTCGACCAACAACATCCTGCATCCGGCCAACGGCGCACCGATCATCGTTCCGTCACAGGA
TATGGTTCTCGGCCTCTATTATCTGTCCATCGTGGCGGAGAAGGAGCCGGGCGAGGGCATGATATTCGCCGATATGGGCG
AGCTACAACATGCGCTTGAAAACAAGGTCGTCACGCTGCACACCAAGATCAAGGGCCGTTTCAAGACGGTCGATGCCGAA
GGCAACCCTGTGTCGAAGATTTACGACACGACGCCGGGCCGCATGATCATGGGTGAATTGCTGCCGAAGAACGTCAACGT
TCCGTTCGATATCTGCAATCAGGAGATGACCAAGAAGAACATCTCCAAGATGATCGACCATGTTTACCGCCATTGCGGCC
AGAAAGAGACGGTTATCTTCTGTGACCGCATCATGCAGCTTGGTTTTGCCCATGCTTGCCGTGCGGGTATCTCCTTCGGC
AAGGATGACATGGTCATCCCGGAATCGAAGGCCAAGATCGTTGCGGAAACCGAAGCGCTTACGACCGAATACGAACAGCA
GTACAATGACGGCCTGATTACGCAGGGCGAAAAGTACAACAAGGTCGTTGACGCCTGGGGCAAGGCAACCGACAAGATCA
CCGAAGAGATGATGGCGCGCCTGAAGGCCGTCGAATTCGATCCGGTGACCGGTCGCCAGAAGCAGATGAACTCGGTCTAC
ATGATGTCGCATTCGGGTGCCCGTGGTTCGGTCAACCAGATGCGCCAGCTTGGCGGCATGCGGGGCCTGATGGCCAAGCC
GTCGGGTGAAATCATCGAGACCCCGATCATCTCGAACTTCAAGGAAGGCCTGACCGTGAACGAGTACTTCAACTCGACCC
ACGGCGCCCGCAAGGGTCTGGCAGACACCGCCTTGAAGACGGCCAACTCGGGCTACCTGACCCGTCGTCTCGTTGACGTT
GCACAGGATGCGATTATTTCGGAAGTCGATTGCGGCGCCGAAATCGGTCTCACCATGCAGCCCATCGTCGATGCCGGCCA
GATCGTCGCCTCGATCGGCCAGCGCGTTCTGGGCCGTACGGCTCTCGATCCGATCCTGCATCCGGTAACCGGCGAAGTCA
TCGTCGAGGCTGGCCGCATGGTCGAGGAGAAGGACGTCGAGATCATCGAGAAGGCTGGCATCCAGTCGATTCGCATCCGT
TCGGCCCTCACCTGTGAAACCCGCAACGGCGTTTGCGCCAAGTGCTATGGCCGCGACCTTGCACGCGGCACGCCGGTCAA
CCAGGGTGAAGCTGTCGGCGTTATCGCCGCTCAGTCGATCGGCGAGCCGGGCACCCAGCTCACCATGCGTACCTTCCACT
TGGGCGGTACCGCACAGGTGGTCGACAGCTCCTATCTTGAAGCTTCGTATGAAGGCACCGTCAAGCTGCGCAACCGCAAT
GTGGTTCGCAACTCCGATGGCAACCTCGTGGTGATGGGCCGTAACATGGCTGTCCTGATCCTCGACGCTACGGGCAAGGA
ACGTGCGGTCCATCGCGTGACCTATGGTTCGCGTCTGTTCGTGGACGAGGGCGATACGGTCAAGCGCGGCCAGCGCATTG
CCGAGTGGGATCCGTATACCCGTCCGATCATGACGGAAGTTGAAGGCTACGTTGAGTTTGAAGATCTCGTCGATGGTCTG
TCGGTTTCGGAAACGGCCGACGAGTCGACTGGTATCACCAAGCGCGTTGTCATCGACTGGCGTTCGACCCCGCGCGGTTC
GGATCTCAAGCCTGCCATGGTCATCAAGGACAAGGCCGGCAAGATCCTGAAACTGTCGAAGGGTGGCGATGCCCGCTTCC
TGCTCTCCGTGGAATCGATCCTTTCGGTTGAGCCGGGCGCGCATGTGAAGGCTGGCGACGTTATCGCCCGTCTGCCGATG
GAAAGCGCCAAGACCAAGGACATCACCGGTGGTCTGCCGCGCGTGGCTGAACTGTTTGAAGCTCGCCGTCCGAAGGACCA
CGCCATCATCGCCGAGATCGATGGTACCGTCCGTTTCGGTCGCGACTACAAGAACAAGCGCCGCATCATTATCGAGCCGA
ACGACGATACGATCGAGCCGGTTGAGTATCTCATTCCGAAGGGCAAGCCGTTCCATCTTCAGGACGGTGACGTCATCGAA
AAGGGTGAGTATATCCTCGACGGCAACCCGGCACCGCATGACATTCTGGCGATCAAGGGCGTGGAAGCTCTGGCTTCCTA
CCTCGTGAACGAAATCCAGGAAGTCTATCGCTTGCAGGGCGTTTTGATCAACGACAAGCACATCGAAGTGATCGTTCGCC
AGATGTTGCAGAAGGTGGAAATCACGGAATCCGGCGATACCGGCTATATTCCGGGTGACCACGTTGACCGCATCGAGCTG
GAAGAGATCAACGAACGTCTTATCGAAGAAGGCAAGAAGCCGGGCTCCGGCAATCCTGTCCTCCTCGGTATCACCAAGGC
TTCGCTGCAGACGCCTTCGTTCATCTCGGCCGCGTCGTTCCAGGAAACGACCCGTGTGCTGACCGAAGCTGCGGTTGCCG
GTAAGATGGACACGTTGCAGGGTCTCAAGGAAAACGTCATCGTCGGCCGTCTCATCCCGGCCGGTACTGGCGGCATGGCC
AACCAGATCCGTCGCATCGCAACCGCGCGCGACGAACTGATTATCGACGAACGTCGCAAGACTTCCGGTTCGGCCGAAGC
AAATGCGATGCTGGTTGATATGACCGACAACGCTGCCGAATAA

Upstream 100 bases:

>100_bases
CACAACTGCATAATACCGCGATTTCTTTTCAGGATGGCAGGGATTTTCAACTTGTCATCGACGTCACACAGGGCGGCGGA
TCGCCCTTAAGGAGAACGGC

Downstream 100 bases:

>100_bases
AATCGGCAAACGGTAAACTGAAAAAGGCCGCCTTTCGGGGCGGCCTTTCTGTTTTCAGCGCAGGATAAAAAAGAGCCGGT
CGGAACCGGCGCTTTCTTTC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1400; Mature: 1400

Protein sequence:

>1400_residues
MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQL
LSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMI
MKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKGRFKTVDAE
GNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFG
KDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVY
MMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMVEEKDVEIIEKAGIQSIRIR
SALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRN
VVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGL
SVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPM
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIEL
EEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMA
NQIRRIATARDELIIDERRKTSGSAEANAMLVDMTDNAAE

Sequences:

>Translated_1400_residues
MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQL
LSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMI
MKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKGRFKTVDAE
GNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFG
KDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVY
MMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMVEEKDVEIIEKAGIQSIRIR
SALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRN
VVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGL
SVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPM
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIEL
EEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMA
NQIRRIATARDELIIDERRKTSGSAEANAMLVDMTDNAAE
>Mature_1400_residues
MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQL
LSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMI
MKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKGRFKTVDAE
GNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFG
KDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVY
MMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDV
AQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMVEEKDVEIIEKAGIQSIRIR
SALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRN
VVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGL
SVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPM
ESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIEL
EEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMA
NQIRRIATARDELIIDERRKTSGSAEANAMLVDMTDNAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=933, Percent_Identity=24.6516613076099, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI39725938, Length=697, Percent_Identity=26.8292682926829, Blast_Score=150, Evalue=1e-35,
Organism=Homo sapiens, GI103471997, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=1e-17,
Organism=Escherichia coli, GI2367335, Length=1396, Percent_Identity=59.025787965616, Blast_Score=1675, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=570, Percent_Identity=25.6140350877193, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=310, Percent_Identity=31.6129032258064, Blast_Score=137, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=899, Percent_Identity=23.3592880978865, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=734, Percent_Identity=26.566757493188, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324917, Length=635, Percent_Identity=25.511811023622, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281360912, Length=659, Percent_Identity=27.01062215478, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17530899, Length=491, Percent_Identity=26.2729124236253, Blast_Score=147, Evalue=8e-35,
Organism=Drosophila melanogaster, GI17647875, Length=379, Percent_Identity=25.5936675461741, Blast_Score=104, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155560; Mature: 155560

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHHCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCCHHHHHHHHHHHEECCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCHHHH
LIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEEECCC
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
NKVVTLHTKIKGRFKTVDAEGNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKN
CCEEEEEEEECCEEEEECCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCHHHHCHHHHHHH
ISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPESKAKIVAETEAL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHH
TTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVY
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEE
MMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALDPILHPVTGEVIVEAGRMVEEKDVEIIEKAGIQSIRIRSALTCETRNGVCAKCYGRDL
HHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEHHCCHH
ARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCC
VVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYT
EEECCCCCEEEEECCEEEEEEECCCCCHHEEEEECCCEEEEECCCHHHHCCCCCCCCCCC
RPIMTEVEGYVEFEDLVDGLSVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAG
CCHHHHHHCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCC
KILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFE
CEEEEECCCCEEEEEEEHHHHCCCCCCCEECCCHHEECCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIE
HCCCCCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEECCCCCEEE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCC
ITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASF
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
QETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMANQIRRIATARDELIIDERRK
HHHHHHHHHHHHHCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEHHHC
TSGSAEANAMLVDMTDNAAE
CCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHHCCEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCCHHHHHHHHHHHEECCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCHHHH
LIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCEEECCC
EARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALE
CEEEEEEECCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
NKVVTLHTKIKGRFKTVDAEGNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKN
CCEEEEEEEECCEEEEECCCCCCCHHHCCCCCCHHHHHHHCCCCCCCCHHHHCHHHHHHH
ISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPESKAKIVAETEAL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHH
TTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVY
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEE
MMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGL
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHCCCHHHHHCCCCHHHCCH
ADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALDPILHPVTGEVIVEAGRMVEEKDVEIIEKAGIQSIRIRSALTCETRNGVCAKCYGRDL
HHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEHHCCHH
ARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCC
VVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYT
EEECCCCCEEEEECCEEEEEEECCCCCHHEEEEECCCEEEEECCCHHHHCCCCCCCCCCC
RPIMTEVEGYVEFEDLVDGLSVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAG
CCHHHHHHCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCC
KILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFE
CEEEEECCCCEEEEEEEHHHHCCCCCCCEECCCHHEECCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIE
HCCCCCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEECCCCCEEE
KGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVE
CCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCC
ITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASF
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
QETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMANQIRRIATARDELIIDERRK
HHHHHHHHHHHHHCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEHHHC
TSGSAEANAMLVDMTDNAAE
CCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA