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The map label for this gene is sdaA [H]

Identifier: 225852672

GI number: 225852672

Start: 1172139

End: 1173542

Strand: Reverse

Name: sdaA [H]

Synonym: BMEA_A1220

Alternate gene names: 225852672

Gene position: 1173542-1172139 (Counterclockwise)

Preceding gene: 225852673

Following gene: 225852671

Centisome position: 55.21

GC content: 59.19

Gene sequence:

>1404_bases
ATGTTTCTGTCGGTTTTTGATCTTTACAAGATTGGCATCGGGCCTTCCAGCTCGCATACCATGGGGCCGATGACGGCTGC
CAATATGTTCTTCGACGAAATTATCGGTAGGGACTGGCCAAAGCCGGCCAATGCGAAAATCTACCGTCTCAAGGCCAGCC
TGCACGGTTCGCTTGCCTATACCGGCATCGGCCATGCCACCGACCGCGCGGTCATCCTTGGCCTTTGTGGATACCGGCCC
GATACGATCGATCCCGACATCATAGATGCGGAAGTCGCCCGTGTGGCTGCGGAAAAGACAGTGCAGCCGGAAGGCCATCC
CGCTTATCATTTCGATCCGAAAACCGATCTGGTCATGGATCGCAAGACGCCGCTTCCCGGACACGCCAACGGGATGGCAT
TCGAGGCTTATGACCGGGACGACCGGCTTTTGCTGCGCCGTGCCTATTTTTCCATTGGCGGCGGTTTCGTCGTTACAGCG
GAAGAACTGAGCCGCGTGCAGACCAGTGGCAACAAGGTCGACAACGGGGCCAATGTGCCTTATCCGTTCCGCAATGCAGC
CGAAATGCTCGAAATGGCTCACGCCAGCGGTCTTTCGATTGCAGAGATGAAGCGCGCAAACGAAGAATGTTGCATGGCGC
GCGTTGATCTGGATCATGGCCTGGACCGGATATGGGGCGCGATGCGCGATTGCATCGAGCGTGGGCTCAGCCGCGATGGT
GTCATGCCGGGCGGGTTGAATGTGCGGCGGCGCGCGCGCCAGTTGCATGACAAGCTTCAGGAAGACTGGCGCAACAATCG
CAGCAACCCGCTGCTCGCCAATGACTGGCTGTCGGTTTACGCCATGGCCGTCAACGAGGAGAACGCTTCCGGTGGCAGGG
TGGTGACGGCGCCCACAAACGGAGCTGCGGGTGTGGTTCCCGCAGTGCTGCGTTATTATCTCCATTTCCATAGCGATGCG
GACGAGAAGGGCATTCGCGATTTTCTGCTGACATCTGCCGCTATTGGCGGCGTCATCAAGCACAATGCATCCATTTCCGG
TGCGGAAGTGGGGTGTCAGGGCGAAGTCGGCTCGGCATCGGCCATGGCGGCTGCGGGCCTTGCGGCCGTTCTGGGCGGCT
CGCCGGAGCAGATTGAAAATGCGGCGGAAATTGCGCTGGAACATCACCTTGGCATGACATGCGATCCGATTGCCGGGCTG
GTTCAGGTGCCGTGCATCGAGCGCAATGCGCTTGGTGCGGTCAAGGCCGTTACGGCTGCTTCTCTTGCGGTCAAGGGGGA
TGGCAAGCATTTCGTGCCTCTTGATGCCTGCATTGAAACAATGCGCCAGACCGGACACGATATGAGCGAGCGTTACAAGG
AAACGAGCCAGGGCGGGCTGGCGGTCAACGTTGTTGCCTGCTGA

Upstream 100 bases:

>100_bases
AAGCGCGGGGCCCTTGCCAGCCGCGTTTGGCGATGGCCTTCAGGCGCGTTGCCTGGCCAACAATCAGGCACCCGGATGAA
GGGGTGCAGCAGGTGTGGGA

Downstream 100 bases:

>100_bases
ACAGTGACCGTTTAAGTGGATCAATTTTGTTGCATCACACTGCGCAAAACTACTTCGCGCTTTTGCTGGAATGCTCTAGA
TCAGAATCATGGCTCTAAAT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFLSVFDLYKIGIGPSSSHTMGPMTAANMFFDEIIGRDWPKPANAKIYRLKASLHGSLAYTGIGHATDRAVILGLCGYRP
DTIDPDIIDAEVARVAAEKTVQPEGHPAYHFDPKTDLVMDRKTPLPGHANGMAFEAYDRDDRLLLRRAYFSIGGGFVVTA
EELSRVQTSGNKVDNGANVPYPFRNAAEMLEMAHASGLSIAEMKRANEECCMARVDLDHGLDRIWGAMRDCIERGLSRDG
VMPGGLNVRRRARQLHDKLQEDWRNNRSNPLLANDWLSVYAMAVNEENASGGRVVTAPTNGAAGVVPAVLRYYLHFHSDA
DEKGIRDFLLTSAAIGGVIKHNASISGAEVGCQGEVGSASAMAAAGLAAVLGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLAVKGDGKHFVPLDACIETMRQTGHDMSERYKETSQGGLAVNVVAC

Sequences:

>Translated_467_residues
MFLSVFDLYKIGIGPSSSHTMGPMTAANMFFDEIIGRDWPKPANAKIYRLKASLHGSLAYTGIGHATDRAVILGLCGYRP
DTIDPDIIDAEVARVAAEKTVQPEGHPAYHFDPKTDLVMDRKTPLPGHANGMAFEAYDRDDRLLLRRAYFSIGGGFVVTA
EELSRVQTSGNKVDNGANVPYPFRNAAEMLEMAHASGLSIAEMKRANEECCMARVDLDHGLDRIWGAMRDCIERGLSRDG
VMPGGLNVRRRARQLHDKLQEDWRNNRSNPLLANDWLSVYAMAVNEENASGGRVVTAPTNGAAGVVPAVLRYYLHFHSDA
DEKGIRDFLLTSAAIGGVIKHNASISGAEVGCQGEVGSASAMAAAGLAAVLGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLAVKGDGKHFVPLDACIETMRQTGHDMSERYKETSQGGLAVNVVAC
>Mature_467_residues
MFLSVFDLYKIGIGPSSSHTMGPMTAANMFFDEIIGRDWPKPANAKIYRLKASLHGSLAYTGIGHATDRAVILGLCGYRP
DTIDPDIIDAEVARVAAEKTVQPEGHPAYHFDPKTDLVMDRKTPLPGHANGMAFEAYDRDDRLLLRRAYFSIGGGFVVTA
EELSRVQTSGNKVDNGANVPYPFRNAAEMLEMAHASGLSIAEMKRANEECCMARVDLDHGLDRIWGAMRDCIERGLSRDG
VMPGGLNVRRRARQLHDKLQEDWRNNRSNPLLANDWLSVYAMAVNEENASGGRVVTAPTNGAAGVVPAVLRYYLHFHSDA
DEKGIRDFLLTSAAIGGVIKHNASISGAEVGCQGEVGSASAMAAAGLAAVLGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLAVKGDGKHFVPLDACIETMRQTGHDMSERYKETSQGGLAVNVVAC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=465, Percent_Identity=47.741935483871, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1789161, Length=467, Percent_Identity=46.8950749464668, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1788116, Length=465, Percent_Identity=46.0215053763441, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 50107; Mature: 50107

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDLYKIGIGPSSSHTMGPMTAANMFFDEIIGRDWPKPANAKIYRLKASLHGSLAY
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEE
TGIGHATDRAVILGLCGYRPDTIDPDIIDAEVARVAAEKTVQPEGHPAYHFDPKTDLVMD
CCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEC
RKTPLPGHANGMAFEAYDRDDRLLLRRAYFSIGGGFVVTAEELSRVQTSGNKVDNGANVP
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YPFRNAAEMLEMAHASGLSIAEMKRANEECCMARVDLDHGLDRIWGAMRDCIERGLSRDG
CCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHEEHHCHHHCHHHHHHHHHHHHHHCCCCCC
VMPGGLNVRRRARQLHDKLQEDWRNNRSNPLLANDWLSVYAMAVNEENASGGRVVTAPTN
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHEEEEEEECCCCCCCCEEEECCCC
GAAGVVPAVLRYYLHFHSDADEKGIRDFLLTSAAIGGVIKHNASISGAEVGCQGEVGSAS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMAAAGLAAVLGGSPEQIENAAEIALEHHLGMTCDPIAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SLAVKGDGKHFVPLDACIETMRQTGHDMSERYKETSQGGLAVNVVAC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MFLSVFDLYKIGIGPSSSHTMGPMTAANMFFDEIIGRDWPKPANAKIYRLKASLHGSLAY
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEE
TGIGHATDRAVILGLCGYRPDTIDPDIIDAEVARVAAEKTVQPEGHPAYHFDPKTDLVMD
CCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEC
RKTPLPGHANGMAFEAYDRDDRLLLRRAYFSIGGGFVVTAEELSRVQTSGNKVDNGANVP
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YPFRNAAEMLEMAHASGLSIAEMKRANEECCMARVDLDHGLDRIWGAMRDCIERGLSRDG
CCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHEEHHCHHHCHHHHHHHHHHHHHHCCCCCC
VMPGGLNVRRRARQLHDKLQEDWRNNRSNPLLANDWLSVYAMAVNEENASGGRVVTAPTN
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHEEEEEEECCCCCCCCEEEECCCC
GAAGVVPAVLRYYLHFHSDADEKGIRDFLLTSAAIGGVIKHNASISGAEVGCQGEVGSAS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
AMAAAGLAAVLGGSPEQIENAAEIALEHHLGMTCDPIAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SLAVKGDGKHFVPLDACIETMRQTGHDMSERYKETSQGGLAVNVVAC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]