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The map label for this gene is ycfF [C]

Identifier: 225852665

GI number: 225852665

Start: 1165862

End: 1166284

Strand: Direct

Name: ycfF [C]

Synonym: BMEA_A1211

Alternate gene names: 225852665

Gene position: 1165862-1166284 (Clockwise)

Preceding gene: 225852664

Following gene: 225852668

Centisome position: 54.85

GC content: 53.66

Gene sequence:

>423_bases
ATGTCCGCCACTTACGACGACAACAATATCTTCGCCAAAATCTTGCGCGGTGAAATTCCATCCACCCGCGTTTATGAAAC
AGACAGCGTTGTGGCTTTCATGGATGTCATGCCCCAGGGCAAAGGCCATACGCTTGTGGCGCCGAAGGCTCCGTCGCGCA
ATCTTCTGGACGCCAGGCCGGAAACGCTCGCCGATGTCATCCAGGCTGTGCAGAAAATCGCCAATGCAGTGAAAAAGGCG
TTCAATGCTGATGGCGTGACTGTGATGCAGTTCAACGAACCGGCTTCAGGCCAGACGGTCTATCACCTGCATTTCCATGT
CATTCCGCGCTTTGAAGGCGTGGCGCTGAAACCGCATAGCGGCCAGATGGAAGATCCTGCCGTTCTTTCAGAAAACGCTG
AGAAAATTCGCGCATCTCTTTGA

Upstream 100 bases:

>100_bases
AAGAACACTCCCCTTACCGGAAAGCATAGGCCAGCCCGGCTTGCCTTACCGGTCGGGATAAAGTCTGATCGCCATGAAAA
TATGCATTGGAGAGAATCGA

Downstream 100 bases:

>100_bases
AAAAAGATATTTTTTGCGATTAGTATTCACTGCCATGGCAGCACCATTTTGCTGACGGCAGATGGTAGTTTAATAAAAAC
GGCCCCGAAGGGCCGTTTTT

Product: histidine triad protein

Products: GTP; GMP

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVAPKAPSRNLLDARPETLADVIQAVQKIANAVKKA
FNADGVTVMQFNEPASGQTVYHLHFHVIPRFEGVALKPHSGQMEDPAVLSENAEKIRASL

Sequences:

>Translated_140_residues
MSATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVAPKAPSRNLLDARPETLADVIQAVQKIANAVKKA
FNADGVTVMQFNEPASGQTVYHLHFHVIPRFEGVALKPHSGQMEDPAVLSENAEKIRASL
>Mature_139_residues
SATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVAPKAPSRNLLDARPETLADVIQAVQKIANAVKKAF
NADGVTVMQFNEPASGQTVYHLHFHVIPRFEGVALKPHSGQMEDPAVLSENAEKIRASL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI261278358, Length=94, Percent_Identity=36.1702127659575, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI4503719, Length=94, Percent_Identity=36.1702127659575, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=108, Percent_Identity=38.8888888888889, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: 3.6.1.17

Molecular weight: Translated: 15301; Mature: 15169

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVAPKAPSRNLLDARP
CCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCH
ETLADVIQAVQKIANAVKKAFNADGVTVMQFNEPASGQTVYHLHFHVIPRFEGVALKPHS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCEEECCCC
GQMEDPAVLSENAEKIRASL
CCCCCCHHHHCCHHHHHHCC
>Mature Secondary Structure 
SATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVAPKAPSRNLLDARP
CCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCH
ETLADVIQAVQKIANAVKKAFNADGVTVMQFNEPASGQTVYHLHFHVIPRFEGVALKPHS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCEEECCCC
GQMEDPAVLSENAEKIRASL
CCCCCCHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: P1,P4-bis(5'-guanosyl) tetraphosphate; H2O

Specific reaction: P1,P4-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]