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The map label for this gene is nagZ [H]

Identifier: 225852391

GI number: 225852391

Start: 874579

End: 875598

Strand: Direct

Name: nagZ [H]

Synonym: BMEA_A0917

Alternate gene names: 225852391

Gene position: 874579-875598 (Clockwise)

Preceding gene: 225852390

Following gene: 225852392

Centisome position: 41.14

GC content: 59.22

Gene sequence:

>1020_bases
ATGAAAGAGTGCAAGGCATGGATTGCCGGTATATCCGGCACGAAGCTCACCCCGGACGAGATTGCCTTCTTCCGGGATGA
AACCCCGTGGGGCTTCATTCTTTTTGCTCGCAATGTGGAAAGCCTCGAACAGGTGAGCGAGCTCACCGCCCATCTGCGTG
ACCTGACGGGGCTGGACCAGACGCCGGTTTTCATCGATCAGGAGGGCGGGCGCGTGCAGCGCCTTCGCCCGCCGCTGGTA
CCGAACTATCCGTCCGCGTCCGAAATTGGCGCGATCTATGCACGCGACAAGGAAAAGGGGTTGCGTGCCGCCTGGCTCCA
TGCCCGGCTCCATGCTTTCGATCTGTTGAAGGTCGGCGTCAATGCGGATTGCCTGCCGGTTCTGGATGTGCCGGTGGAGG
GCGCGCATGATGTGATCGGAATGCGGGCCTATTCCAAAAACCCCCATGCGGTTGCGGAAATGGGACGCGCTGCCGCCGAA
GGTCTTCTGGCTGGCGGCGTTCTTCCCGTCGTGAAGCATATGCCGGGCCATGGCCGCGCCTTTTCCGATACGCATAAGGA
ACTGGCGCGGGTCAGCGTTGCGCTCAACGAACTGGTTGCGCATGATTTCGTGCCGTTCAAGGCGCTCAATGATCTGCCGA
TGGCCATGACCGCCCATGTGGTGTTCGATTGCATCGACCCGGAAAGACCGTCCACGCTTTCGCCGACGGTTATTAATACG
ATCATTCGCGATGTGATCGGGTTCGACGGCCTTGTCATCAGTGACGACATTTCCATGAAGGCATTGTCCGGCGATCTTGG
CGATATAACCGACGGCATCGTTACGGCGGGCTGCGATATCGTGCTCTATTGCTCAGGCGTTATGGAGGAACTGGTAAAGG
TTGCCGCCCGTGTGCCGGTTCTGGATGGCAAAGCAAAGCGCCGGGCCGAACTGGCGGAAGTCTATGCGGGCGACCCCGAT
CTTTCCGACGAGGACGAGGTGCGCGCCGAATTCAATGCCATGTTTGAACCGATAGCGTAA

Upstream 100 bases:

>100_bases
AATTCGTCACCACAGCCTACAGCCTACCAAGCGGCCGTTTTTTCGGCTAAACCCGGCGGAGGCGAGTTTGATTCAGCAAG
ACAATTCGAGGAAAAGCCGC

Downstream 100 bases:

>100_bases
TCGGCAAAACTTGATAAACTTGTTCCTGCTGGCAGAATCTGTGCCGGCAGGGGCAACAGCAGGACGACAGGCTTGGCAGC
ATCGGATGCACATACAGGTG

Product: beta-hexosaminidase A

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKECKAWIAGISGTKLTPDEIAFFRDETPWGFILFARNVESLEQVSELTAHLRDLTGLDQTPVFIDQEGGRVQRLRPPLV
PNYPSASEIGAIYARDKEKGLRAAWLHARLHAFDLLKVGVNADCLPVLDVPVEGAHDVIGMRAYSKNPHAVAEMGRAAAE
GLLAGGVLPVVKHMPGHGRAFSDTHKELARVSVALNELVAHDFVPFKALNDLPMAMTAHVVFDCIDPERPSTLSPTVINT
IIRDVIGFDGLVISDDISMKALSGDLGDITDGIVTAGCDIVLYCSGVMEELVKVAARVPVLDGKAKRRAELAEVYAGDPD
LSDEDEVRAEFNAMFEPIA

Sequences:

>Translated_339_residues
MKECKAWIAGISGTKLTPDEIAFFRDETPWGFILFARNVESLEQVSELTAHLRDLTGLDQTPVFIDQEGGRVQRLRPPLV
PNYPSASEIGAIYARDKEKGLRAAWLHARLHAFDLLKVGVNADCLPVLDVPVEGAHDVIGMRAYSKNPHAVAEMGRAAAE
GLLAGGVLPVVKHMPGHGRAFSDTHKELARVSVALNELVAHDFVPFKALNDLPMAMTAHVVFDCIDPERPSTLSPTVINT
IIRDVIGFDGLVISDDISMKALSGDLGDITDGIVTAGCDIVLYCSGVMEELVKVAARVPVLDGKAKRRAELAEVYAGDPD
LSDEDEVRAEFNAMFEPIA
>Mature_339_residues
MKECKAWIAGISGTKLTPDEIAFFRDETPWGFILFARNVESLEQVSELTAHLRDLTGLDQTPVFIDQEGGRVQRLRPPLV
PNYPSASEIGAIYARDKEKGLRAAWLHARLHAFDLLKVGVNADCLPVLDVPVEGAHDVIGMRAYSKNPHAVAEMGRAAAE
GLLAGGVLPVVKHMPGHGRAFSDTHKELARVSVALNELVAHDFVPFKALNDLPMAMTAHVVFDCIDPERPSTLSPTVINT
IIRDVIGFDGLVISDDISMKALSGDLGDITDGIVTAGCDIVLYCSGVMEELVKVAARVPVLDGKAKRRAELAEVYAGDPD
LSDEDEVRAEFNAMFEPIA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=280, Percent_Identity=32.5, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 36727; Mature: 36727

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKECKAWIAGISGTKLTPDEIAFFRDETPWGFILFARNVESLEQVSELTAHLRDLTGLDQ
CCHHHHHHHCCCCCCCCHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
TPVFIDQEGGRVQRLRPPLVPNYPSASEIGAIYARDKEKGLRAAWLHARLHAFDLLKVGV
CCEEEECCCCCEECCCCCCCCCCCCHHHHHEEEECCHHCCHHHHHHHHHHHHHHHHHCCC
NADCLPVLDVPVEGAHDVIGMRAYSKNPHAVAEMGRAAAEGLLAGGVLPVVKHMPGHGRA
CCCCEEEECCCCCCCHHHHEEHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
FSDTHKELARVSVALNELVAHDFVPFKALNDLPMAMTAHVVFDCIDPERPSTLSPTVINT
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
IIRDVIGFDGLVISDDISMKALSGDLGDITDGIVTAGCDIVLYCSGVMEELVKVAARVPV
HHHHHHCCCCEEEECCCCHHHHCCCCHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHCCC
LDGKAKRRAELAEVYAGDPDLSDEDEVRAEFNAMFEPIA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKECKAWIAGISGTKLTPDEIAFFRDETPWGFILFARNVESLEQVSELTAHLRDLTGLDQ
CCHHHHHHHCCCCCCCCHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
TPVFIDQEGGRVQRLRPPLVPNYPSASEIGAIYARDKEKGLRAAWLHARLHAFDLLKVGV
CCEEEECCCCCEECCCCCCCCCCCCHHHHHEEEECCHHCCHHHHHHHHHHHHHHHHHCCC
NADCLPVLDVPVEGAHDVIGMRAYSKNPHAVAEMGRAAAEGLLAGGVLPVVKHMPGHGRA
CCCCEEEECCCCCCCHHHHEEHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
FSDTHKELARVSVALNELVAHDFVPFKALNDLPMAMTAHVVFDCIDPERPSTLSPTVINT
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
IIRDVIGFDGLVISDDISMKALSGDLGDITDGIVTAGCDIVLYCSGVMEELVKVAARVPV
HHHHHHCCCCEEEECCCCHHHHCCCCHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHCCC
LDGKAKRRAELAEVYAGDPDLSDEDEVRAEFNAMFEPIA
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA