Click here to switch to the map view.

The map label for this gene is cobT [H]

Identifier: 225852379

GI number: 225852379

Start: 861250

End: 862269

Strand: Direct

Name: cobT [H]

Synonym: BMEA_A0905

Alternate gene names: 225852379

Gene position: 861250-862269 (Clockwise)

Preceding gene: 225852375

Following gene: 225852383

Centisome position: 40.52

GC content: 62.25

Gene sequence:

>1020_bases
ATGAGCGCCAGCGGCCTTCCCTTTGACGATTTCCGTGAATTGATCCGCAATCTGCCGGGGCCGGATTTAGGCGCGGAACG
GGCTGTTCGCGAACGCGAGGTGACGTTGACCAAGCCCGCCGGTTCGCTCGGGCGGCTGGAGGAGATTGTTGCATGGCTTG
CCACATGGACGGGCAAACGCACGCCACAGGTCAATCGCCCGCTGGTCGCCGTATTCGCGGGCAATCACGGCGTCACGGCA
AAGAACATCACGCCGTTCCCGCCGAGCGTGACAGCGCAGATGGTTGAAAACTTCGCCGCCGGTGGCGCTGCCATCAACCA
GATTTGCATTGCCAACGATCTGGGACTGAAAGTGTTCGATCTCGCGCTGGAGCATCCGACCGGCGATATTACCGAAGAAG
CGGCCATGGATGAACGCACCTGCGCCGCCACCATGGCTTTCGGCATGGAAGCGATCGCGGGCGGCACCGACCTTCTTTGC
ATCGGTGAAATGGGGATCGGCAACACGACCATTGCGGCAGCGATTGCGCTTGCGCTTTTCGGCGGCACGGCTGAAGACTG
GGTGGGGCCGGGTACGGGTTCCACGGGTGAACTGATGCAGCGAAAGCTTGCCGCCGTTCGTCAGGCAGTCGCGCTCCATC
AGCCGCATTTGCAGGATCCACTGGAAGTGCTGCGCTGCCTGGGCGGGCGCGAGATCGCGGCCATGGCAGGCGCAATCCTT
GCCGCGCGCATGGAGAAAATTCCGGTCATCGTCGATGGTTTTGTGGCAAGCGCGGCTGCTGCCGTGCTCTATGCGGCCAA
CCCGGAAGCCATCGATCATTGCATGTTCGGCCAGGTCTCGGCAGAGCCGGGGCATCGCAAGCTTCTGGCAAAGATGGGCA
AGGAGCCGCTTCTTGACCTTGGAATGCGCCTTGGTGAAGGCACCGGCGCGGCCCTTGCAGCCAATATCGTCAAGGCGGCG
GCGCTATGCCATAGCGGCATGGCTACCTTCGAGCAGGCCGGTGTTTCCGCCTCGAAATAA

Upstream 100 bases:

>100_bases
TATTGTTTCAGATCAAAGAGGTGATTTGAAAATTCGCGTCAGTGCTTATAGGACGAGCCCAACGAATTTACACCTCCCAT
CATTGATTGGACTTTACGAT

Downstream 100 bases:

>100_bases
GAGACTTTCCTGAAAAGCCCGCCGATCCGGCGGGCTTTTCATTCTGAATGACGACCCCCGAGCATTTTCGAGCCAAAAGT
GCGAAGCGCCTTTGCGGGGG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTA
KNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLC
IGEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAIL
AARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAA
ALCHSGMATFEQAGVSASK

Sequences:

>Translated_339_residues
MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTA
KNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLC
IGEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAIL
AARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAA
ALCHSGMATFEQAGVSASK
>Mature_338_residues
SASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTAK
NITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLCI
GEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAILA
ARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAAA
LCHSGMATFEQAGVSASK

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=342, Percent_Identity=31.5789473684211, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35127; Mature: 34996

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKR
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCC
TPQVNRPLVAVFAGNHGVTAKNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFD
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEE
LALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAIALALF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
GGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAIL
CCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHH
AARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDL
HHHHHHCCEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHH
GMRLGEGTGAALAANIVKAAALCHSGMATFEQAGVSASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKR
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCC
TPQVNRPLVAVFAGNHGVTAKNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFD
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEE
LALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAIALALF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
GGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAIL
CCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHH
AARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDL
HHHHHHCCEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHH
GMRLGEGTGAALAANIVKAAALCHSGMATFEQAGVSASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA