Click here to switch to the map view.

The map label for this gene is nuoC [H]

Identifier: 225852320

GI number: 225852320

Start: 801890

End: 802498

Strand: Direct

Name: nuoC [H]

Synonym: BMEA_A0846

Alternate gene names: 225852320

Gene position: 801890-802498 (Clockwise)

Preceding gene: 225852319

Following gene: 225852321

Centisome position: 37.72

GC content: 56.81

Gene sequence:

>609_bases
ATGAGCGAAGAAGCTCTCGGTGAACTTTCCGGCTATATCAGGGAACGTCTCGGCGACGCGATCGAAGAGGCGAATCTGGC
TTATGGCGAACTGACGCTTTGCGTGCCGGTGGCGAGCCTCATCGGCGTTCTGACTTTCCTGCGTGACGATGTGCAGTGCC
AGTTCGTCAATCTGACCGATATTTCAGGCGTCGATTATCCGCAGCGCGAAAAGCGCTTCGATGTCGTCTACCAGCTTCTG
TCTCCGCGCCAGAACCAGCGCATCCGCGTCAAGGTTCAGGCGGACGAAGATACGCTGGTGCCGTCTGCCGTTCCGGTCTT
CTTCGGCGCGGAATGGTATGAGCGCGAGGCCTACGATATGTACGGCATTCTGTTCTCTGGCCATCCGGACTTGCGCCGCA
TCCTGACGGACTATGGCTTTGAGGGCCATCCGCTGCGCAAGGACTTCCCGCTCACCGGTTTCGTCGAGGTTCGTTATAAC
GACGAACTGAAGCGCGTTGTTTACGAGCCTGTGCAGTTGCGCCAGGAATTCCGCAATTTCGATTTTCTCTCGCCGTGGGA
AGGAACGGATTACGTTCTGCCCGGTGATGAGAAAGCAAAGACGAACTGA

Upstream 100 bases:

>100_bases
CGGTTTGCGCACACTAAATTTGTTAGGGTTCTGCTGCTGCCCCGCAAGGGCCTCCCAAAACAAAGCAGGCGGCATGAGTT
CTAAAGAAGGAAGTTAGAAA

Downstream 100 bases:

>100_bases
GCGACAGGAAGCTGAACATGGCTGAGACTCAGGTCCGCAATTTCAATATCAACTTCGGCCCGCAGCATCCTGCCGCGCAC
GGCGTGTTGCGTCTGGTGCT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTFLRDDVQCQFVNLTDISGVDYPQREKRFDVVYQLL
SPRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYN
DELKRVVYEPVQLRQEFRNFDFLSPWEGTDYVLPGDEKAKTN

Sequences:

>Translated_202_residues
MSEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTFLRDDVQCQFVNLTDISGVDYPQREKRFDVVYQLL
SPRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYN
DELKRVVYEPVQLRQEFRNFDFLSPWEGTDYVLPGDEKAKTN
>Mature_201_residues
SEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTFLRDDVQCQFVNLTDISGVDYPQREKRFDVVYQLLS
PRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYND
ELKRVVYEPVQLRQEFRNFDFLSPWEGTDYVLPGDEKAKTN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=189, Percent_Identity=54.4973544973545, Blast_Score=216, Evalue=2e-56,
Organism=Escherichia coli, GI145693162, Length=191, Percent_Identity=32.4607329842932, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=53.5135135135135, Blast_Score=206, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=53.5135135135135, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24656494, Length=188, Percent_Identity=54.2553191489362, Blast_Score=207, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23344; Mature: 23212

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTFLRDDVQCQFVNLTD
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
ISGVDYPQREKRFDVVYQLLSPRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDM
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHH
YGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYNDELKRVVYEPVQLRQEFRNF
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
DFLSPWEGTDYVLPGDEKAKTN
CCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
SEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTFLRDDVQCQFVNLTD
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
ISGVDYPQREKRFDVVYQLLSPRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDM
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHH
YGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYNDELKRVVYEPVQLRQEFRNF
EEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
DFLSPWEGTDYVLPGDEKAKTN
CCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA