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The map label for this gene is era [H]

Identifier: 225852184

GI number: 225852184

Start: 672784

End: 673719

Strand: Direct

Name: era [H]

Synonym: BMEA_A0700

Alternate gene names: 225852184

Gene position: 672784-673719 (Clockwise)

Preceding gene: 225852183

Following gene: 225852185

Centisome position: 31.65

GC content: 57.59

Gene sequence:

>936_bases
ATGAATAATGGGACATCGCCTGCTGGCGGCGAAACGGAAGCGACGCAGACCCGTTCGGGTTTTGTGGCGCTCATCGGGGC
GCCGAATGCCGGCAAATCCACGTTGGTCAACCAGCTTGTGGGCACGAAGGTTTCGATTGTCACGCATAAGGTGCAGACGA
CGCGTGCGCTGGTGCGCGGCATCTTCATCGAAGGGCCGGCGCAGATCGTTCTGGTGGACACGCCGGGCATTTTCCGCCCG
AAGCGCAGGCTGGACCGCGCCATGGTTACGACCGCCTGGGGCGGTGCGAAAGATGCGGATATCATTCTGGTCATCATCGA
TGCGCAGGGCGGTTTCAATGAAAATGCCGAGGCGCTGCTCGAAAGCATGAAGGATGTTCGCCAGAAGAAAGTTCTGGTTC
TGAACAAGGTGGATCGTGTCGATCCGCCGGTTCTACTGTCATTGGCGCAAAAGGCCAACGAACTGGTTCCTTTCGACAGG
ACTTTCATGATTTCCGCCCTGAACGGCTCGGGCTGCAAGGATCTGGCCAAATACCTGGCCGAAAGCGTTCCGAACGGCCC
GTGGTATTACCCGGAAGACCAGATTTCCGACATGCCGATGCGCCAGCTTGCCGCTGAAATCACGCGCGAAAAGCTCTATC
TTCGCCTGCATGAAGAACTGCCCTATGCTTCCACCGTGGAAACCGAGCGATGGGAAGAGCGCAAGGATGGTTCGGTACGT
ATCGAGCAGGTGATCTATGTCGAGCGCGAAAGCCAGAAGAAGATCGTGCTCGGCCACAAGGGCGAGACGGTGAAGGCAAT
CGGGCAAGCCGCGCGCAAGGAAATTTCGGAAATTCTGGAACAGACGGTTCATCTGTTCCTTTTCGTCAAGGTGCGCGAAA
ACTGGGGCAACGACCCGGAACGCTACCGCGAGATGGGGCTTGATTTCCCGACCTGA

Upstream 100 bases:

>100_bases
GATTGCGACGGTGATCGGCTTGAAAGCGGCTCTGTTGCAACGGGATGCTGTTGCTCAAGGGGAAGGCAACCTCCCGCAAG
AAGGCCTGGAAGGATAAAAA

Downstream 100 bases:

>100_bases
GGAGGAGCGCCGAAAGGCCGGATATCATGGAATGGCGCGATGAAGGCGTAATTCTCGGCACACGTCGCCATGGCGAAACC
AGCGCCATTGTCGAGGTGAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRGIFIEGPAQIVLVDTPGIFRP
KRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALLESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDR
TFMISALNGSGCKDLAKYLAESVPNGPWYYPEDQISDMPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVR
IEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPERYREMGLDFPT

Sequences:

>Translated_311_residues
MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRGIFIEGPAQIVLVDTPGIFRP
KRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALLESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDR
TFMISALNGSGCKDLAKYLAESVPNGPWYYPEDQISDMPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVR
IEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPERYREMGLDFPT
>Mature_311_residues
MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRGIFIEGPAQIVLVDTPGIFRP
KRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALLESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDR
TFMISALNGSGCKDLAKYLAESVPNGPWYYPEDQISDMPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVR
IEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPERYREMGLDFPT

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=32.1875, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=38.4615384615385, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI87082120, Length=167, Percent_Identity=28.1437125748503, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646434, Length=321, Percent_Identity=25.8566978193146, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34671; Mature: 34671

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50823 KH_TYPE_2 ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRG
CCCCCCCCCCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHH
IFIEGPAQIVLVDTPGIFRPKRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALL
HEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
ESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDRTFMISALNGSGCKDLAKYLA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
ESVPNGPWYYPEDQISDMPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVR
HHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEE
IEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPE
EEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
RYREMGLDFPT
HHHHCCCCCCC
>Mature Secondary Structure
MNNGTSPAGGETEATQTRSGFVALIGAPNAGKSTLVNQLVGTKVSIVTHKVQTTRALVRG
CCCCCCCCCCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHH
IFIEGPAQIVLVDTPGIFRPKRRLDRAMVTTAWGGAKDADIILVIIDAQGGFNENAEALL
HEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
ESMKDVRQKKVLVLNKVDRVDPPVLLSLAQKANELVPFDRTFMISALNGSGCKDLAKYLA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
ESVPNGPWYYPEDQISDMPMRQLAAEITREKLYLRLHEELPYASTVETERWEERKDGSVR
HHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEE
IEQVIYVERESQKKIVLGHKGETVKAIGQAARKEISEILEQTVHLFLFVKVRENWGNDPE
EEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
RYREMGLDFPT
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]