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The map label for this gene is fabD [H]

Identifier: 225851993

GI number: 225851993

Start: 476643

End: 477587

Strand: Direct

Name: fabD [H]

Synonym: BMEA_A0492

Alternate gene names: 225851993

Gene position: 476643-477587 (Clockwise)

Preceding gene: 225851983

Following gene: 225851994

Centisome position: 22.42

GC content: 61.69

Gene sequence:

>945_bases
ATGGCGGTAGCATTCACTTTCCCAGGGCAGGGCAGCCAGGCGGTTGGCATGGGCAAGGCTCTGGCCGAACAATTTGCCGA
AGCGCGCGCCGTTTTCGATGAAGTGGATGAGGCGCTGGGCGAAAAGCTTTCCGCCACCATGTTCGAGGGGCCGGAAGATG
TGCTGACGCTGACGGCCAATGCGCAGCCTGCGCTGATGGCGGTTTCCATGGCGGTCCAGCGCATCATGGAAGCGCGCGGC
TTTTCGCTGAAGGACAAGGTTTCTTATGTCGCCGGTCATTCGCTTGGCGAATATTCGGCTCTGTGCGCTGCTGGCACGTT
TTCACTTGCCGACACGGCGCGTCTCTTGCGCATTCGCGGCAATGCCATGCAGAAGGCGGTTCCGGTCGGCGAAGGCGCTA
TGGCGGCGATCATCGGTCTGGAACACGGCGATGTGGAGGCTGTCTGCATGGAAGCAAAGGCTTCCGGCCCGGTCCAGATC
GCCAATGACAATGGCGGCGGCCAGCTTGTCATATCCGGGGCCAGGGCGGCCGTTGAACTGGCCGCGAAGCTTGGCTCTGA
AAAGGGTGCAAAGCGCGCCATCATGCTGCCGGTATCCGCTCCCTTCCATTCGACCCTGATGGCACCGGCGGCTGATGCCA
TGCGCGAGGCGCTTGCAGCGGTTGAAAAGCATGATCCGGTCGTGCCGCTTATCGCCAATGTGCGCGCGGCCCCCGTGACC
GACGCTAACGAGATCGCCGCCCTGCTGGTCGAGCAGGTGACGGGCCAGGTGCGCTGGCGCGAAACTATCGAGTGGTTTTC
TGCCAATGGTGTAACCACGCTTTATGAAGTAGGCTGCGGCAAGGTTCTGACGGGTTTGGCGCGGCGCATCTCCAAGGATG
TATCCGGCGCTGCCGTTGGTTCGGCTGAGGAAATCGAAGCAGCGCTTGCTGCTCTTAACGCTTGA

Upstream 100 bases:

>100_bases
TGTGAGGCACACCGCGCAAAATAATCAATTCGTTACAAGGTGCCCGATCCAAAGAAAAGCTCAGGACGATCGGCTCCATC
TATAGAAAAGACGAGGCATC

Downstream 100 bases:

>100_bases
TCCCGAGAAGTCGCAGACTTTTCGGATAAGACCATGCGCTGAAATTGAGAAGCAAAAAAGGGATTTCGCATGTTTGATCT
GACTGGCCGCAAGGCTCTGG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAVAFTFPGQGSQAVGMGKALAEQFAEARAVFDEVDEALGEKLSATMFEGPEDVLTLTANAQPALMAVSMAVQRIMEARG
FSLKDKVSYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQKAVPVGEGAMAAIIGLEHGDVEAVCMEAKASGPVQI
ANDNGGGQLVISGARAAVELAAKLGSEKGAKRAIMLPVSAPFHSTLMAPAADAMREALAAVEKHDPVVPLIANVRAAPVT
DANEIAALLVEQVTGQVRWRETIEWFSANGVTTLYEVGCGKVLTGLARRISKDVSGAAVGSAEEIEAALAALNA

Sequences:

>Translated_314_residues
MAVAFTFPGQGSQAVGMGKALAEQFAEARAVFDEVDEALGEKLSATMFEGPEDVLTLTANAQPALMAVSMAVQRIMEARG
FSLKDKVSYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQKAVPVGEGAMAAIIGLEHGDVEAVCMEAKASGPVQI
ANDNGGGQLVISGARAAVELAAKLGSEKGAKRAIMLPVSAPFHSTLMAPAADAMREALAAVEKHDPVVPLIANVRAAPVT
DANEIAALLVEQVTGQVRWRETIEWFSANGVTTLYEVGCGKVLTGLARRISKDVSGAAVGSAEEIEAALAALNA
>Mature_313_residues
AVAFTFPGQGSQAVGMGKALAEQFAEARAVFDEVDEALGEKLSATMFEGPEDVLTLTANAQPALMAVSMAVQRIMEARGF
SLKDKVSYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQKAVPVGEGAMAAIIGLEHGDVEAVCMEAKASGPVQIA
NDNGGGQLVISGARAAVELAAKLGSEKGAKRAIMLPVSAPFHSTLMAPAADAMREALAAVEKHDPVVPLIANVRAAPVTD
ANEIAALLVEQVTGQVRWRETIEWFSANGVTTLYEVGCGKVLTGLARRISKDVSGAAVGSAEEIEAALAALNA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=289, Percent_Identity=31.8339100346021, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=43.7908496732026, Blast_Score=219, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=27.3037542662116, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=31.5436241610738, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32361; Mature: 32230

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAFTFPGQGSQAVGMGKALAEQFAEARAVFDEVDEALGEKLSATMFEGPEDVLTLTAN
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AQPALMAVSMAVQRIMEARGFSLKDKVSYVAGHSLGEYSALCAAGTFSLADTARLLRIRG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHC
NAMQKAVPVGEGAMAAIIGLEHGDVEAVCMEAKASGPVQIANDNGGGQLVISGARAAVEL
CHHHHHCCCCCCCEEEEEECCCCCHHHEEEECCCCCCEEEEECCCCCEEEEECHHHHHHH
AAKLGSEKGAKRAIMLPVSAPFHSTLMAPAADAMREALAAVEKHDPVVPLIANVRAAPVT
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
DANEIAALLVEQVTGQVRWRETIEWFSANGVTTLYEVGCGKVLTGLARRISKDVSGAAVG
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHCCCCCCCC
SAEEIEAALAALNA
CHHHHHHHHHHHCC
>Mature Secondary Structure 
AVAFTFPGQGSQAVGMGKALAEQFAEARAVFDEVDEALGEKLSATMFEGPEDVLTLTAN
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AQPALMAVSMAVQRIMEARGFSLKDKVSYVAGHSLGEYSALCAAGTFSLADTARLLRIRG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHC
NAMQKAVPVGEGAMAAIIGLEHGDVEAVCMEAKASGPVQIANDNGGGQLVISGARAAVEL
CHHHHHCCCCCCCEEEEEECCCCCHHHEEEECCCCCCEEEEECCCCCEEEEECHHHHHHH
AAKLGSEKGAKRAIMLPVSAPFHSTLMAPAADAMREALAAVEKHDPVVPLIANVRAAPVT
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
DANEIAALLVEQVTGQVRWRETIEWFSANGVTTLYEVGCGKVLTGLARRISKDVSGAAVG
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHCCCCCCCC
SAEEIEAALAALNA
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]