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The map label for this gene is yhcK [H]

Identifier: 225851949

GI number: 225851949

Start: 438289

End: 439434

Strand: Direct

Name: yhcK [H]

Synonym: BMEA_A0444

Alternate gene names: 225851949

Gene position: 438289-439434 (Clockwise)

Preceding gene: 225851946

Following gene: 225851951

Centisome position: 20.62

GC content: 57.85

Gene sequence:

>1146_bases
ATGACGCTTGTGCCGTTCTCTTTGACGGTCAATCTGACGGTAGCTAGCCTTTTTGTGCTGACTTTCGCCTTTGTTTCCAT
GCAGGAGCGCGGGCATCGTGCACCGCGCTGGTTCACTCTGGCCTTTCTTTGCTCGATGGCGATGCCGCTTTTCGGCTTCG
GGCTTCCAACGACGGAAAATCCACGCATCATCATTCTGGGCTCCTTCGCTGCCATCATGGCCGCGCTGACCCTTCTGGTG
ATCGGCCTTTGTGAAACCTATAGGCAGCGGATCGAATGGCGTTTGCTGGGCTTTTTGTTCATTGCCGCGCTGGCATGCAA
TGCGCTGGTTTTTGAATTGCCGCGCACCTCGCTTCTCCACCGCTTTCTCTACCAGTTGCCGCTTTGCCTGATTGAACTGG
TGACAATCCGTGTGATCTACCGCTCCGGCATGCCGCGCCTGGTGGACAAGCTCCTGATGGCCCTTGCGGTGTTAAGCGTC
GTCCATTTTTTCTCGAAGGCGTTTCTTATCGTCTGGCCCGGCATGGATGCGCGCCCGGAAGACCAGAGCGATACAGGCCA
GGCGATTTTCTCGCTTTCGATGGGCGTTTTCGTGCAGGTTTCGACCGGGTTGCTGCTTTTGCTGCGCACCATGTTGCGCA
TATTGGGCGATGCCAGCGAACAGTCCGAGATCGATGCACTATCGCAGATTTACAATCGCCGTGGCTTCGACCGTCACGTC
ATGCGGCGTCTGATGCGAAAGGGGCCGGATACGCCCTATGCCATCATTATGAGCGATCTCGATTATTTCAAGCGTGTCAA
CGACACTTATGGGCATGACTGCGGTGATCGGGTGATCGAGGCTTTCGGCGGGCTCTTGAGAACGCATCTCCCCAAACCGG
CAGTTGCCGCGCGTATGGGCGGAGAGGAATTCGTGGTCTTTATGCCGGGTGCGGATGCCGTGGCCGCCCATGATCTGGCG
CAGACCCTGCGCACCACCATGACGGCGTTGAGCTTCTCGGGCGATGCCGCCGAGTGGATGCCAACGGCAAGCTTCGGCGT
TGCCGAACACAGGGTCGGCGAGGGCCTTTACGATACGATACGATACGCCGTGCCGATGGCGCGCTTTACGAAGCCAAGAA
GGCTGGACGCAACCGCGTCCATGTAA

Upstream 100 bases:

>100_bases
AAAATGCGCAGCGTATGCAGCGGGAAATGCGTCTGGGAGATGGGGTGGTTGGGGCCCCGGACCCAAGGTGCGGGGGGAGG
CAAGTTGAGGGGGCCTGATA

Downstream 100 bases:

>100_bases
CCTGAAACATAAACCGATCAGCGATTAGCCTTCTCACGCTCCACGGCGCGCCAGCCGATATCAGAACGGTAAAAACCTTC
CGGCCAGTCGATGAGCTTCA

Product: diguanylate cyclase GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTLVPFSLTVNLTVASLFVLTFAFVSMQERGHRAPRWFTLAFLCSMAMPLFGFGLPTTENPRIIILGSFAAIMAALTLLV
IGLCETYRQRIEWRLLGFLFIAALACNALVFELPRTSLLHRFLYQLPLCLIELVTIRVIYRSGMPRLVDKLLMALAVLSV
VHFFSKAFLIVWPGMDARPEDQSDTGQAIFSLSMGVFVQVSTGLLLLLRTMLRILGDASEQSEIDALSQIYNRRGFDRHV
MRRLMRKGPDTPYAIIMSDLDYFKRVNDTYGHDCGDRVIEAFGGLLRTHLPKPAVAARMGGEEFVVFMPGADAVAAHDLA
QTLRTTMTALSFSGDAAEWMPTASFGVAEHRVGEGLYDTIRYAVPMARFTKPRRLDATASM

Sequences:

>Translated_381_residues
MTLVPFSLTVNLTVASLFVLTFAFVSMQERGHRAPRWFTLAFLCSMAMPLFGFGLPTTENPRIIILGSFAAIMAALTLLV
IGLCETYRQRIEWRLLGFLFIAALACNALVFELPRTSLLHRFLYQLPLCLIELVTIRVIYRSGMPRLVDKLLMALAVLSV
VHFFSKAFLIVWPGMDARPEDQSDTGQAIFSLSMGVFVQVSTGLLLLLRTMLRILGDASEQSEIDALSQIYNRRGFDRHV
MRRLMRKGPDTPYAIIMSDLDYFKRVNDTYGHDCGDRVIEAFGGLLRTHLPKPAVAARMGGEEFVVFMPGADAVAAHDLA
QTLRTTMTALSFSGDAAEWMPTASFGVAEHRVGEGLYDTIRYAVPMARFTKPRRLDATASM
>Mature_380_residues
TLVPFSLTVNLTVASLFVLTFAFVSMQERGHRAPRWFTLAFLCSMAMPLFGFGLPTTENPRIIILGSFAAIMAALTLLVI
GLCETYRQRIEWRLLGFLFIAALACNALVFELPRTSLLHRFLYQLPLCLIELVTIRVIYRSGMPRLVDKLLMALAVLSVV
HFFSKAFLIVWPGMDARPEDQSDTGQAIFSLSMGVFVQVSTGLLLLLRTMLRILGDASEQSEIDALSQIYNRRGFDRHVM
RRLMRKGPDTPYAIIMSDLDYFKRVNDTYGHDCGDRVIEAFGGLLRTHLPKPAVAARMGGEEFVVFMPGADAVAAHDLAQ
TLRTTMTALSFSGDAAEWMPTASFGVAEHRVGEGLYDTIRYAVPMARFTKPRRLDATASM

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787802, Length=131, Percent_Identity=30.5343511450382, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082007, Length=109, Percent_Identity=36.697247706422, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787262, Length=115, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081881, Length=162, Percent_Identity=32.7160493827161, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786584, Length=117, Percent_Identity=36.7521367521368, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788381, Length=126, Percent_Identity=31.7460317460317, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 42521; Mature: 42390

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVPFSLTVNLTVASLFVLTFAFVSMQERGHRAPRWFTLAFLCSMAMPLFGFGLPTTEN
CEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PRIIILGSFAAIMAALTLLVIGLCETYRQRIEWRLLGFLFIAALACNALVFELPRTSLLH
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFLYQLPLCLIELVTIRVIYRSGMPRLVDKLLMALAVLSVVHFFSKAFLIVWPGMDARPE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
DQSDTGQAIFSLSMGVFVQVSTGLLLLLRTMLRILGDASEQSEIDALSQIYNRRGFDRHV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHH
MRRLMRKGPDTPYAIIMSDLDYFKRVNDTYGHDCGDRVIEAFGGLLRTHLPKPAVAARMG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCC
GEEFVVFMPGADAVAAHDLAQTLRTTMTALSFSGDAAEWMPTASFGVAEHRVGEGLYDTI
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHCCHHHHHH
RYAVPMARFTKPRRLDATASM
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TLVPFSLTVNLTVASLFVLTFAFVSMQERGHRAPRWFTLAFLCSMAMPLFGFGLPTTEN
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PRIIILGSFAAIMAALTLLVIGLCETYRQRIEWRLLGFLFIAALACNALVFELPRTSLLH
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFLYQLPLCLIELVTIRVIYRSGMPRLVDKLLMALAVLSVVHFFSKAFLIVWPGMDARPE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
DQSDTGQAIFSLSMGVFVQVSTGLLLLLRTMLRILGDASEQSEIDALSQIYNRRGFDRHV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHH
MRRLMRKGPDTPYAIIMSDLDYFKRVNDTYGHDCGDRVIEAFGGLLRTHLPKPAVAARMG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCC
GEEFVVFMPGADAVAAHDLAQTLRTTMTALSFSGDAAEWMPTASFGVAEHRVGEGLYDTI
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHCCHHHHHH
RYAVPMARFTKPRRLDATASM
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]