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The map label for this gene is der [H]

Identifier: 225851918

GI number: 225851918

Start: 408064

End: 409515

Strand: Direct

Name: der [H]

Synonym: BMEA_A0412

Alternate gene names: 225851918

Gene position: 408064-409515 (Clockwise)

Preceding gene: 225851917

Following gene: 225851919

Centisome position: 19.2

GC content: 61.71

Gene sequence:

>1452_bases
ATGGGTTTCACTCTCGCCATTGTCGGGCGTCCGAATGTCGGCAAGTCCACGCTGTTCAACCGCCTCGTCGGCCGCAAACT
GGCGCTGGTGGATGACCTGCCGGGCGTCACACGCGACAGGCGCATCCACGATGCCAAGCTCTACGACCTGAAGTTTCAGG
TCATTGATACGGCTGGTCTTGAAGAAGCGGCCAATGACAGCCTGGAAGCGCGCATGCGCGCCCAGACCGAGGCTGCAATC
AGCGAGGCTGACGCCGTTCTCTTCGTCATCGACGCCAAGGCGGGCATAACGCCTGCTGACAGCACCTTTGCAGAAGCGGT
GCGCCGTTCCGGCAAGCCAGTGGTGCTGGTCGCCAACAAGGCGGAAGCGCGCGGCTCGGAAGCGGGCATGTACGATGCAT
TCCAGCTTGGCCTTGGCGAACCCTGCCCGATTTCCGCCGAGCATGGCCAGGGGATGCCTGATCTGCGCGACGCGATCGTG
GAACTTCTGGGTGAGGAACGCGTCTTTGCCGAGGAGAGGCAGGAGGAAGCCGCAGACGAGGTTTTCACCCCTGCCGCCGT
TGGTGCGCTGGTGGGCGACGATATTGAAGACCCGGATGCGGAAGAAATTCCGGCCTATGACGCCACCAAGCCGCTGCGCA
TCGCCATTGTCGGGCGCCCCAATGCAGGCAAGTCCACTCTCATCAACACGATGCTGGGTGAAGACCGTCTGTTGACGGGG
CCGGAAGCGGGCATCACGCGCGATTCCATCTCCGCCGATTGGGAATGGCATGGCCGTAAGATCAAGCTGTTCGATACCGC
AGGCATGCGCCGCAAGGCGCGCGTGCAGGAAAAGCTCGAAAAGCTTTCCGTGGCCGATAGCCTGCGCGCCATCCGCTTTG
CGGAAGTGGTCATCATCGTGCTCGATGCGACCATTCCGTTTGAAAAGCAGGATTTGCAGATCGCCGATCTCATCATCCGC
GAAGGCCGTGCGCCGGTCATCGCTTTCAACAAATGGGATCTGATCGAAGACCGCCAGATGGTTCTGGCCGATCTTTATGA
GAAGACCGCGCGGCTTCTGCCGCAGGTGCGCGGGCTTCGCGCCGTGCCGATTTCCGGCGAGCGCGGGCAGGGCATCGACA
AGCTCATGGAAAATGTCGTCAAGACCCACGAAATCTGGAATCGCCGCATTTCGACGGGCCGCCTCAACCGCTGGCTGGAA
GGCGTCATTGCCCACCAGCCGCCGCCTGCCGTTTCGGGTCGCCGCCTGAAGGTGAAATATATGACGCAGGTGAAGACCCG
CCCGCCGGGCTTCGTCGTGTCCTGTTCGCGGCCCGACGCCATGCCGCAATCCTATGTGCGCTATCTCATCAACGGCCTGC
GCGAAACCTTCGACATGCCGGGCGTGCCGATAAGGCTTTCCCTGCGAACCTCGGACAATCCGTTCGCAGGCCGCGCGAAA
AAGAAGAAGTGA

Upstream 100 bases:

>100_bases
CGCACCCGCCAATGCGCGCCAGCGCGCCAATATCATGCTGGACCTCATGCACAGCGCGGGCGTTGCGGCGCAGGGCTAAT
TTCTGGAGTAATTTTCATTC

Downstream 100 bases:

>100_bases
TGCAAAGCCCGGAGTGATCCGGGCTTTTTCACAGGCAGCCGAGATCAAGCCATAGCGGATGCGCGGCAGAGCCCGAAATC
TTCATATGAATGCTTGTGTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MGFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGLEEAANDSLEARMRAQTEAAI
SEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANKAEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIV
ELLGEERVFAEERQEEAADEVFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTG
PEAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIVLDATIPFEKQDLQIADLIIR
EGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLRAVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLE
GVIAHQPPPAVSGRRLKVKYMTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAK
KKK

Sequences:

>Translated_483_residues
MGFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGLEEAANDSLEARMRAQTEAAI
SEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANKAEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIV
ELLGEERVFAEERQEEAADEVFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTG
PEAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIVLDATIPFEKQDLQIADLIIR
EGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLRAVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLE
GVIAHQPPPAVSGRRLKVKYMTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAK
KKK
>Mature_482_residues
GFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGLEEAANDSLEARMRAQTEAAIS
EADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANKAEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIVE
LLGEERVFAEERQEEAADEVFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTGP
EAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIVLDATIPFEKQDLQIADLIIRE
GRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLRAVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLEG
VIAHQPPPAVSGRRLKVKYMTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAKK
KK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=475, Percent_Identity=39.3684210526316, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI2367268, Length=167, Percent_Identity=34.7305389221557, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788919, Length=155, Percent_Identity=33.5483870967742, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=162, Percent_Identity=28.3950617283951, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 53312; Mature: 53181

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEHHCCCCCCCCCEECCCEEEEEEEEEEECCCC
EEAANDSLEARMRAQTEAAISEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANK
HHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECC
AEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIVELLGEERVFAEERQEEAADE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTG
HCCHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECC
PEAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIV
CCCCCCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LDATIPFEKQDLQIADLIIREGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLR
EECCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
AVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLEGVIAHQPPPAVSGRRLKVKY
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
MTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAK
EEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
KKK
CCC
>Mature Secondary Structure 
GFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEHHCCCCCCCCCEECCCEEEEEEEEEEECCCC
EEAANDSLEARMRAQTEAAISEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANK
HHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECC
AEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIVELLGEERVFAEERQEEAADE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTG
HCCHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECC
PEAGITRDSISADWEWHGRKIKLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIV
CCCCCCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LDATIPFEKQDLQIADLIIREGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLR
EECCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
AVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLEGVIAHQPPPAVSGRRLKVKY
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
MTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAK
EEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
KKK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA