Click here to switch to the map view.

The map label for this gene is cidA1 [H]

Identifier: 225851870

GI number: 225851870

Start: 357642

End: 358061

Strand: Direct

Name: cidA1 [H]

Synonym: BMEA_A0363

Alternate gene names: 225851870

Gene position: 357642-358061 (Clockwise)

Preceding gene: 225851864

Following gene: 225851871

Centisome position: 16.82

GC content: 61.43

Gene sequence:

>420_bases
ATGAACGCCCCCCGCAAAGCCCATGACCTGAAGATCCGCTTGCGCTATGCGCTGCACAACAGCCGTTTGATGCAGATTGC
AACGCTGGTCGGCTTCTGGCTGGCGGGTGAGGCGGTCGTGCGGCTTGCCGGTTTGCCGCTGCCGGGCGGCATTGTGGGCA
TGGCGCTGGTTCTGGCCCTGCTTCTTAGCGGTCGCATCAGCCTTTTCAGTATGAAGCGCGGCGCGGAATGGTTTCTGGCC
GAAATGCTGCTCTTCTTTATCCCGGCGGTTCTGGCGATCCTTGAACATCGCGAGCTGATCGGAATGCTGGGACTCAAGAT
CATGGCGGTCATCCTGCTCGGCACGCTCACGGTCATGAGCGTTACCGCGCTGACGGTGGACCTCTGCTACCGCTGGAGCC
TGCGTTATGCTGCCCGGTGA

Upstream 100 bases:

>100_bases
GCCGTAATGAAATCAATTCATTTATAGAATAGAGCGCCGGAGGTTATATTCAGCATGAGCAAAGGCATTATCTGCCTGAA
CCGGCACAGGAAAGACCGCC

Downstream 100 bases:

>100_bases
TCCCCTGGGTAATCCCTTTGTGGCGACGCTGTTCTGGTCGGCGGCCACGATCCTTCTCTATCTTGCGGCAAAGCGGGTCT
ATCGCCGTTTTCCCCTGTGG

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MNAPRKAHDLKIRLRYALHNSRLMQIATLVGFWLAGEAVVRLAGLPLPGGIVGMALVLALLLSGRISLFSMKRGAEWFLA
EMLLFFIPAVLAILEHRELIGMLGLKIMAVILLGTLTVMSVTALTVDLCYRWSLRYAAR

Sequences:

>Translated_139_residues
MNAPRKAHDLKIRLRYALHNSRLMQIATLVGFWLAGEAVVRLAGLPLPGGIVGMALVLALLLSGRISLFSMKRGAEWFLA
EMLLFFIPAVLAILEHRELIGMLGLKIMAVILLGTLTVMSVTALTVDLCYRWSLRYAAR
>Mature_139_residues
MNAPRKAHDLKIRLRYALHNSRLMQIATLVGFWLAGEAVVRLAGLPLPGGIVGMALVLALLLSGRISLFSMKRGAEWFLA
EMLLFFIPAVLAILEHRELIGMLGLKIMAVILLGTLTVMSVTALTVDLCYRWSLRYAAR

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15373; Mature: 15373

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPRKAHDLKIRLRYALHNSRLMQIATLVGFWLAGEAVVRLAGLPLPGGIVGMALVLAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLSGRISLFSMKRGAEWFLAEMLLFFIPAVLAILEHRELIGMLGLKIMAVILLGTLTVMS
HHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALTVDLCYRWSLRYAAR
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAPRKAHDLKIRLRYALHNSRLMQIATLVGFWLAGEAVVRLAGLPLPGGIVGMALVLAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLSGRISLFSMKRGAEWFLAEMLLFFIPAVLAILEHRELIGMLGLKIMAVILLGTLTVMS
HHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALTVDLCYRWSLRYAAR
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]