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The map label for this gene is ccpA [H]

Identifier: 225851736

GI number: 225851736

Start: 217047

End: 218069

Strand: Direct

Name: ccpA [H]

Synonym: BMEA_A0214

Alternate gene names: 225851736

Gene position: 217047-218069 (Clockwise)

Preceding gene: 225851735

Following gene: 225851738

Centisome position: 10.21

GC content: 59.73

Gene sequence:

>1023_bases
ATGGCCGCGACGGGCAAAAGAGCAACGATACATGATGTGGCGCGCCTTGCTGGCGTGTCGATCAAGACTGTTTCGCGCGT
CTATAACGACGAGCCGAACGTGCGCGAAGCCATACGCGAAAAAGTAAAACAGGCCGGTGCGCAACTGCGCTATCGCCCCA
ATGTGGCGGCACGCAATCTGGTCGAGCGCCGCTCGCACCTGATCGGCCTTTTCTTTGAAAACCCGAGCTCCAGTTATGTC
ACCGAATTGCAGATGGGCGCACTCGAACGCCTGCGTGGCACGCGCTACCGGCTCCTGATCTTTCCGGTCGAAAACCGGGC
CGATATTCGCGGTGCGCTGATCGAAACCGCCCATGCTTTCGGTCTTGACGGCATCATCGTCACACCCCCCATGTCGGATG
ACCCGGACATTTTGCAGGAATTGACGGCCTCGGCCATGCCTTTCGCGCGTGTGGCGGGGGATGCGAATGTGCATCCGACC
GACAGCGTCACCATCGACGACGAGGCGGCGGCTGTCGATCTGATGCACTATCTCCTGGAACTCGGTCATCGAAAGATCGC
CATCGTGATTGGCGATCCGACACACCGTTCTGCCGAATTGCGCCTGGAAGGCTATCGCCGCGCGCTGCGTGAGGCGGGGA
TCGAAGGCAATTCCGATTATGAGGTGCAGGGCGGGTTCAGTTTTGCAAGCGGCCTTGTGGCGGGCCGCAAGCTGCTTTCG
CTCCCGAACAGGCCGACCGCCATCTTCGCCTCCAATGACGATATGGCAGCCGCCGTGATGCAGGTCGCCTATGATGCCGG
GATCGCCGTTCCCGATGATCTTACGGTCGTCGGTTTTGACGATAGTGCGATTGCAACTATGGTCTCGCCGCAGATCACCA
CTGTTCGCCAGCCGATTTTCGAGATGACGCGGGATGCCGCCGATATGCTTTTGCGCCAGATGGAGAGCGGGGAAACCTCG
CCTGCACAGCGGATCGACTATAAGCTCATCGTTCGCCAGTCTTCCGCCAGAGTTCCTGCCTAG

Upstream 100 bases:

>100_bases
CGGTTTCTGACGCGCTCGCGCGTTTGTTCGGTTCCCTGATTTCCCTTTTCGTTTCGCGGCGAAGCGGTTAGTTAGAAAAC
AGACAGGGAAGACGATCCGC

Downstream 100 bases:

>100_bases
AACGCGTTTCGAGCGGTTTTGCACTTGCCTTTATCCAGAAACAGGGCCGGAATATTCCCGGCCCTGCCGTCCATATCTGG
ATGCTGGCTTGTTACAGAAC

Product: alanine racemase

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAATGKRATIHDVARLAGVSIKTVSRVYNDEPNVREAIREKVKQAGAQLRYRPNVAARNLVERRSHLIGLFFENPSSSYV
TELQMGALERLRGTRYRLLIFPVENRADIRGALIETAHAFGLDGIIVTPPMSDDPDILQELTASAMPFARVAGDANVHPT
DSVTIDDEAAAVDLMHYLLELGHRKIAIVIGDPTHRSAELRLEGYRRALREAGIEGNSDYEVQGGFSFASGLVAGRKLLS
LPNRPTAIFASNDDMAAAVMQVAYDAGIAVPDDLTVVGFDDSAIATMVSPQITTVRQPIFEMTRDAADMLLRQMESGETS
PAQRIDYKLIVRQSSARVPA

Sequences:

>Translated_340_residues
MAATGKRATIHDVARLAGVSIKTVSRVYNDEPNVREAIREKVKQAGAQLRYRPNVAARNLVERRSHLIGLFFENPSSSYV
TELQMGALERLRGTRYRLLIFPVENRADIRGALIETAHAFGLDGIIVTPPMSDDPDILQELTASAMPFARVAGDANVHPT
DSVTIDDEAAAVDLMHYLLELGHRKIAIVIGDPTHRSAELRLEGYRRALREAGIEGNSDYEVQGGFSFASGLVAGRKLLS
LPNRPTAIFASNDDMAAAVMQVAYDAGIAVPDDLTVVGFDDSAIATMVSPQITTVRQPIFEMTRDAADMLLRQMESGETS
PAQRIDYKLIVRQSSARVPA
>Mature_339_residues
AATGKRATIHDVARLAGVSIKTVSRVYNDEPNVREAIREKVKQAGAQLRYRPNVAARNLVERRSHLIGLFFENPSSSYVT
ELQMGALERLRGTRYRLLIFPVENRADIRGALIETAHAFGLDGIIVTPPMSDDPDILQELTASAMPFARVAGDANVHPTD
SVTIDDEAAAVDLMHYLLELGHRKIAIVIGDPTHRSAELRLEGYRRALREAGIEGNSDYEVQGGFSFASGLVAGRKLLSL
PNRPTAIFASNDDMAAAVMQVAYDAGIAVPDDLTVVGFDDSAIATMVSPQITTVRQPIFEMTRDAADMLLRQMESGETSP
AQRIDYKLIVRQSSARVPA

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=312, Percent_Identity=35.8974358974359, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790369, Length=346, Percent_Identity=30.3468208092486, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789068, Length=328, Percent_Identity=30.4878048780488, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=30.2395209580838, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=32.5503355704698, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=29.0419161676647, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788474, Length=316, Percent_Identity=31.6455696202532, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=27.5541795665635, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=24.6835443037975, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789456, Length=337, Percent_Identity=23.7388724035608, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=22.7564102564103, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787906, Length=332, Percent_Identity=25, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37126; Mature: 36995

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATGKRATIHDVARLAGVSIKTVSRVYNDEPNVREAIREKVKQAGAQLRYRPNVAARNL
CCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHH
VERRSHLIGLFFENPSSSYVTELQMGALERLRGTRYRLLIFPVENRADIRGALIETAHAF
HHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GLDGIIVTPPMSDDPDILQELTASAMPFARVAGDANVHPTDSVTIDDEAAAVDLMHYLLE
CCCCEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHH
LGHRKIAIVIGDPTHRSAELRLEGYRRALREAGIEGNSDYEVQGGFSFASGLVAGRKLLS
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHC
LPNRPTAIFASNDDMAAAVMQVAYDAGIAVPDDLTVVGFDDSAIATMVSPQITTVRQPIF
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHH
EMTRDAADMLLRQMESGETSPAQRIDYKLIVRQSSARVPA
HHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCC
>Mature Secondary Structure 
AATGKRATIHDVARLAGVSIKTVSRVYNDEPNVREAIREKVKQAGAQLRYRPNVAARNL
CCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHH
VERRSHLIGLFFENPSSSYVTELQMGALERLRGTRYRLLIFPVENRADIRGALIETAHAF
HHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GLDGIIVTPPMSDDPDILQELTASAMPFARVAGDANVHPTDSVTIDDEAAAVDLMHYLLE
CCCCEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHH
LGHRKIAIVIGDPTHRSAELRLEGYRRALREAGIEGNSDYEVQGGFSFASGLVAGRKLLS
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHC
LPNRPTAIFASNDDMAAAVMQVAYDAGIAVPDDLTVVGFDDSAIATMVSPQITTVRQPIF
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHH
EMTRDAADMLLRQMESGETSPAQRIDYKLIVRQSSARVPA
HHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]