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The map label for this gene is cysQ [H]

Identifier: 225851726

GI number: 225851726

Start: 206643

End: 207488

Strand: Direct

Name: cysQ [H]

Synonym: BMEA_A0203

Alternate gene names: 225851726

Gene position: 206643-207488 (Clockwise)

Preceding gene: 225851725

Following gene: 225851728

Centisome position: 9.72

GC content: 61.35

Gene sequence:

>846_bases
ATGAAAATTTCCGCCTCTCCAAAAGCAGGCCTTGATGGCACAGCCTTGCGAGCCGTCCTTCGCGACGCTGCGCTTGAGGC
TGGCCGCAGCATCATGAAGCATTATGTCAATGGATGCGCGGTGCAGAGCAAGAAGGATGCCTCGCCCGTAACCGAGGCGG
ATCACGCAGCGGAAGCCATTATTCTTGCGGCCCTGTCGTCGGCCTGCCCCGATGTGCCGGTGGTGGCGGAGGAAGAAGTT
GCAGCAGGGCGCTTGCCGGATCATCTGGGGCGCAAATTCCTTCTGGTCGATCCGCTGGACGGAACCCGGGAATTCCTGCT
GCGCAACGGCGATTTTACGGTCAATATCGGCCTTGTCGAAGAGGGCGCGCCAGTACTGGGTATCGTCTATGCACCGGCCC
GCAATCTGCTGTTTATCGGTAGCGATGCGGGTGCATGGGCAATGGAAACCACACCGGACCATGGCGCAGGCCAGGACCAG
CGGATTTTTGCGCGGGTTTCGCCCGCCGAAAAAGTGGCTGTCTGTAGCCGCTCGCACCTGACGCCTGAAACCGAACGATT
TCTCGCTGAAAACCGCATCGCAAGCAGCGTTTCGGTTGGTTCCTCGCTTAAATTCTGCATTCTTGCCAAGGGTGAGGCGG
ATATTTATCCGCGTTTCGGCCCGACGATGGAATGGGACACGGCGGCGGGCGATGCGGTGCTGCGCGCGGCGGGCGGCATG
ACCGCCACTCTCGACGGCAGGCCGATGATCTATGGCCAGCGCCTCCGTGCAGGGGCGGCGGGTTTCGCCAATCCCGATTT
CGTGGCCTATGGGGCGGGTGAGGCGCCTGTTTTCACCACGGCCTGA

Upstream 100 bases:

>100_bases
CGGGAAGGACCGTTGACGAACTCATCGCCGAGGTGGAAAACTACCTTGCCGAACGTGGTGTGATCGGCAGTTATGGCAGC
GATTCCTGGTCGATCTGAAA

Downstream 100 bases:

>100_bases
CGGCAATGGCGGGCCATTTCCAATGCCTCATTGTCGCATCCATGAGCAGCGGCAAAAAAATACGTGCTATGCTCTTGCGG
CTTGAAATCTTGAGCGTTAT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKISASPKAGLDGTALRAVLRDAALEAGRSIMKHYVNGCAVQSKKDASPVTEADHAAEAIILAALSSACPDVPVVAEEEV
AAGRLPDHLGRKFLLVDPLDGTREFLLRNGDFTVNIGLVEEGAPVLGIVYAPARNLLFIGSDAGAWAMETTPDHGAGQDQ
RIFARVSPAEKVAVCSRSHLTPETERFLAENRIASSVSVGSSLKFCILAKGEADIYPRFGPTMEWDTAAGDAVLRAAGGM
TATLDGRPMIYGQRLRAGAAGFANPDFVAYGAGEAPVFTTA

Sequences:

>Translated_281_residues
MKISASPKAGLDGTALRAVLRDAALEAGRSIMKHYVNGCAVQSKKDASPVTEADHAAEAIILAALSSACPDVPVVAEEEV
AAGRLPDHLGRKFLLVDPLDGTREFLLRNGDFTVNIGLVEEGAPVLGIVYAPARNLLFIGSDAGAWAMETTPDHGAGQDQ
RIFARVSPAEKVAVCSRSHLTPETERFLAENRIASSVSVGSSLKFCILAKGEADIYPRFGPTMEWDTAAGDAVLRAAGGM
TATLDGRPMIYGQRLRAGAAGFANPDFVAYGAGEAPVFTTA
>Mature_281_residues
MKISASPKAGLDGTALRAVLRDAALEAGRSIMKHYVNGCAVQSKKDASPVTEADHAAEAIILAALSSACPDVPVVAEEEV
AAGRLPDHLGRKFLLVDPLDGTREFLLRNGDFTVNIGLVEEGAPVLGIVYAPARNLLFIGSDAGAWAMETTPDHGAGQDQ
RIFARVSPAEKVAVCSRSHLTPETERFLAENRIASSVSVGSSLKFCILAKGEADIYPRFGPTMEWDTAAGDAVLRAAGGM
TATLDGRPMIYGQRLRAGAAGFANPDFVAYGAGEAPVFTTA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=43.4959349593496, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788882, Length=230, Percent_Identity=29.5652173913043, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17537869, Length=259, Percent_Identity=28.1853281853282, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71995897, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29424; Mature: 29424

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISASPKAGLDGTALRAVLRDAALEAGRSIMKHYVNGCAVQSKKDASPVTEADHAAEAI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHH
ILAALSSACPDVPVVAEEEVAAGRLPDHLGRKFLLVDPLDGTREFLLRNGDFTVNIGLVE
HHHHHHHCCCCCCCEECCHHHCCCCCHHHCCEEEEEECCCCCHHHEEECCCEEEEEEEEE
EGAPVLGIVYAPARNLLFIGSDAGAWAMETTPDHGAGQDQRIFARVSPAEKVAVCSRSHL
CCCCEEEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHCCCC
TPETERFLAENRIASSVSVGSSLKFCILAKGEADIYPRFGPTMEWDTAAGDAVLRAAGGM
CCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCE
TATLDGRPMIYGQRLRAGAAGFANPDFVAYGAGEAPVFTTA
EEEECCCCEEECHHHCCCCCCCCCCCEEEECCCCCCEEECC
>Mature Secondary Structure
MKISASPKAGLDGTALRAVLRDAALEAGRSIMKHYVNGCAVQSKKDASPVTEADHAAEAI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHH
ILAALSSACPDVPVVAEEEVAAGRLPDHLGRKFLLVDPLDGTREFLLRNGDFTVNIGLVE
HHHHHHHCCCCCCCEECCHHHCCCCCHHHCCEEEEEECCCCCHHHEEECCCEEEEEEEEE
EGAPVLGIVYAPARNLLFIGSDAGAWAMETTPDHGAGQDQRIFARVSPAEKVAVCSRSHL
CCCCEEEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHCCCC
TPETERFLAENRIASSVSVGSSLKFCILAKGEADIYPRFGPTMEWDTAAGDAVLRAAGGM
CCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCE
TATLDGRPMIYGQRLRAGAAGFANPDFVAYGAGEAPVFTTA
EEEECCCCEEECHHHCCCCCCCCCCCEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]