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The map label for this gene is yggW [C]

Identifier: 225851708

GI number: 225851708

Start: 187422

End: 188636

Strand: Direct

Name: yggW [C]

Synonym: BMEA_A0183

Alternate gene names: 225851708

Gene position: 187422-188636 (Clockwise)

Preceding gene: 225851707

Following gene: 225851709

Centisome position: 8.82

GC content: 60.49

Gene sequence:

>1215_bases
ATGAACAAGCTGTTTCCCCCTTTGCAGGCCAAAAATGCTGCCAGCACCTATCCCGTCATGCATGCTGATGGGGAAACCGC
CTTTGGCATTTATGTGCACTGGCCGTTCTGTCTGGCCAAATGCCCTTATTGCGATTTCAACAGCCATGTCCGCCACAAGC
CGGTGGATCAGGCGCGCTATGGCGCGGCTTTCCGGCGCGAGATGGAAACCTTGCGTGAGCGCACAGGCCCGCGCACCGTC
ACCAGCATTTTCCTGGGCGGCGGCACACCATCGCTGATGCAGCCGGAAACCGTGGGCGCTCTGCTGGATGGCATCGCATC
GTATTGGTCTGTGGCGCCGGACATTGAAATGACGCTGGAAGCCAATCCGACAAGCGTTGAGGCCGACCGTTTTCGCGGCT
ATCGTGCGGCAGGCGTTAACCGGGTGTCGCTTGGTATTCAGGCGTTGAACGATCCCGATCTGCGCCGCCTTGGCCGGATG
CATTCGGTTGCAGAGGCAAAGGCCGCGATCCGGCTGGCACGCGAGATTTTCCCGCGCCTTTCCTTCGACCTTATCTATGC
GCGGCCGGACCAGACAATCGAGGCCTGGCGCGAGGAATTGAAGGAGGCGATCGGCCTTGCTGCCGACCATCTGTCGCTCT
ACCAGCTTACCATCGAGGAAGGCACGCAGTTCTATAATCTCTGGAAGGCGGGCAAGCTCACCACGCCGGAGCCGGACCTT
GCAGCCGCGCTCTATGAGGAAACGCAGCGTGTGACCGCCGAACATGGCCTTCCGGCCTATGAGATTTCCAACCATGCGGT
GCCGGGGCGGGAATCGCAGCACAATCTCGTCTATTGGCGTTATGGCCAATATGCTGGCATCGGGCCCGGCGCACATGGCC
GTTTCGTGGAAAATGACGTGCGCACCGTGACCATGACTGAAAAGCATCCTGAAACATGGCTTGACCATGTGGAGCGGCGC
GGCCACGGAATTATCGAGGAAGAATATCTCGATGGCGGGCAGGAGGGCGATGAATTCCTGATGATGGGCCTGCGCCTGCG
CGAAGGCATCGACCTTGCCCGTTACGCGCGGCTTTCCGGCCATGCGATCGACGACAAACGGCTGGCAAAGCTGATCGCGG
AAGGCATGATCGAGCCGATGGGCGGCAGCCTGATCCGCGCAACGCCGGATGGCGCGCTGGTGCTGGATGCACTGGTTGCC
GATCTGGCGGCATAA

Upstream 100 bases:

>100_bases
ATGGCTGGAAGCCGGGTGACGCCAGCGCGCTGTCGCACCGGGCCCGCGCCTTCAAGCTTTTTGCCGAAAAGGCACTCAAC
GTGGTATCGGCTCCGGCAGA

Downstream 100 bases:

>100_bases
AAGGGCCTGGGATGACTGACGAAACGGGTGAAGAACGGCGCGAATATGTGGTGGGGGGCACGACGATGCGCGCCCGTCCG
CTGGAGCCTGCGCTCTATAT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNKLFPPLQAKNAASTYPVMHADGETAFGIYVHWPFCLAKCPYCDFNSHVRHKPVDQARYGAAFRREMETLRERTGPRTV
TSIFLGGGTPSLMQPETVGALLDGIASYWSVAPDIEMTLEANPTSVEADRFRGYRAAGVNRVSLGIQALNDPDLRRLGRM
HSVAEAKAAIRLAREIFPRLSFDLIYARPDQTIEAWREELKEAIGLAADHLSLYQLTIEEGTQFYNLWKAGKLTTPEPDL
AAALYEETQRVTAEHGLPAYEISNHAVPGRESQHNLVYWRYGQYAGIGPGAHGRFVENDVRTVTMTEKHPETWLDHVERR
GHGIIEEEYLDGGQEGDEFLMMGLRLREGIDLARYARLSGHAIDDKRLAKLIAEGMIEPMGGSLIRATPDGALVLDALVA
DLAA

Sequences:

>Translated_404_residues
MNKLFPPLQAKNAASTYPVMHADGETAFGIYVHWPFCLAKCPYCDFNSHVRHKPVDQARYGAAFRREMETLRERTGPRTV
TSIFLGGGTPSLMQPETVGALLDGIASYWSVAPDIEMTLEANPTSVEADRFRGYRAAGVNRVSLGIQALNDPDLRRLGRM
HSVAEAKAAIRLAREIFPRLSFDLIYARPDQTIEAWREELKEAIGLAADHLSLYQLTIEEGTQFYNLWKAGKLTTPEPDL
AAALYEETQRVTAEHGLPAYEISNHAVPGRESQHNLVYWRYGQYAGIGPGAHGRFVENDVRTVTMTEKHPETWLDHVERR
GHGIIEEEYLDGGQEGDEFLMMGLRLREGIDLARYARLSGHAIDDKRLAKLIAEGMIEPMGGSLIRATPDGALVLDALVA
DLAA
>Mature_404_residues
MNKLFPPLQAKNAASTYPVMHADGETAFGIYVHWPFCLAKCPYCDFNSHVRHKPVDQARYGAAFRREMETLRERTGPRTV
TSIFLGGGTPSLMQPETVGALLDGIASYWSVAPDIEMTLEANPTSVEADRFRGYRAAGVNRVSLGIQALNDPDLRRLGRM
HSVAEAKAAIRLAREIFPRLSFDLIYARPDQTIEAWREELKEAIGLAADHLSLYQLTIEEGTQFYNLWKAGKLTTPEPDL
AAALYEETQRVTAEHGLPAYEISNHAVPGRESQHNLVYWRYGQYAGIGPGAHGRFVENDVRTVTMTEKHPETWLDHVERR
GHGIIEEEYLDGGQEGDEFLMMGLRLREGIDLARYARLSGHAIDDKRLAKLIAEGMIEPMGGSLIRATPDGALVLDALVA
DLAA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=299, Percent_Identity=42.4749163879599, Blast_Score=249, Evalue=3e-66,
Organism=Escherichia coli, GI1789325, Length=376, Percent_Identity=36.7021276595745, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI87082341, Length=261, Percent_Identity=27.9693486590038, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44955; Mature: 44955

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLFPPLQAKNAASTYPVMHADGETAFGIYVHWPFCLAKCPYCDFNSHVRHKPVDQARY
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECHHHHHCCCCCCCCCCCCCCCCHHHHH
GAAFRREMETLRERTGPRTVTSIFLGGGTPSLMQPETVGALLDGIASYWSVAPDIEMTLE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
ANPTSVEADRFRGYRAAGVNRVSLGIQALNDPDLRRLGRMHSVAEAKAAIRLAREIFPRL
CCCCCCCHHHHCCCHHCCCCEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFDLIYARPDQTIEAWREELKEAIGLAADHLSLYQLTIEEGTQFYNLWKAGKLTTPEPDL
CEEEEEECCCHHHHHHHHHHHHHHCCHHHCCEEEEEEHHHCCHHHHHHHCCCCCCCCHHH
AAALYEETQRVTAEHGLPAYEISNHAVPGRESQHNLVYWRYGQYAGIGPGAHGRFVENDV
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCC
RTVTMTEKHPETWLDHVERRGHGIIEEEYLDGGQEGDEFLMMGLRLREGIDLARYARLSG
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
HAIDDKRLAKLIAEGMIEPMGGSLIRATPDGALVLDALVADLAA
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKLFPPLQAKNAASTYPVMHADGETAFGIYVHWPFCLAKCPYCDFNSHVRHKPVDQARY
CCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECHHHHHCCCCCCCCCCCCCCCCHHHHH
GAAFRREMETLRERTGPRTVTSIFLGGGTPSLMQPETVGALLDGIASYWSVAPDIEMTLE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
ANPTSVEADRFRGYRAAGVNRVSLGIQALNDPDLRRLGRMHSVAEAKAAIRLAREIFPRL
CCCCCCCHHHHCCCHHCCCCEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFDLIYARPDQTIEAWREELKEAIGLAADHLSLYQLTIEEGTQFYNLWKAGKLTTPEPDL
CEEEEEECCCHHHHHHHHHHHHHHCCHHHCCEEEEEEHHHCCHHHHHHHCCCCCCCCHHH
AAALYEETQRVTAEHGLPAYEISNHAVPGRESQHNLVYWRYGQYAGIGPGAHGRFVENDV
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCC
RTVTMTEKHPETWLDHVERRGHGIIEEEYLDGGQEGDEFLMMGLRLREGIDLARYARLSG
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
HAIDDKRLAKLIAEGMIEPMGGSLIRATPDGALVLDALVADLAA
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]