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The map label for this gene is regB [H]

Identifier: 225851669

GI number: 225851669

Start: 148776

End: 150068

Strand: Direct

Name: regB [H]

Synonym: BMEA_A0140

Alternate gene names: 225851669

Gene position: 148776-150068 (Clockwise)

Preceding gene: 225851664

Following gene: 225851670

Centisome position: 7.0

GC content: 60.94

Gene sequence:

>1293_bases
ATGCACGCAGAATTCGAGAATCGCGCTTCCAATCTTTCGCGCCGCCCGCGCCTCACAACGCTGGTGCGTGTGCGCTGGCT
GGCTATTGCCGGGCAGACGGCAGCCGTCATGTTCGTGGCGCTTTATCTGCAATTTCCCTTTTCGGTCGGCATCTGTTTCG
CGCTCATTGCCTGTTCGGCCTGGCTCAACCTCTATCTGGCCTTCCGCTTCCCGGCCAACCATCGGCTTAACCCGACAGCG
GCAAGCCTCGTTCTGGCGTTTGACGTGCTGCAACTGGCGGGGCTGCTCTATCTCACCGGCGGGCTGCAAAATCCTTTCAT
CGTCCTGATGATCGTGCCGGTCATCATCTCGGCGACCTCTCTTTCCGCGCGCGACACGATAGTGCTGGCGCTGCTGGTGG
TCGCCTGCACCTCGTTTCTCACCATTCATTACGATCCCTTGCCTTGGTATCCGGGCGAAACGCTGAACCTGCCCCTGCTT
TTCGTGATCGGCATCTGGTGCGCGATCATTTCCGCGCTGGGCTTCACAGGCGTTTACGCCTATCGCATTGCCGAAGAAGC
GCGCCAGCTTGGCGATGCCCTGAGCGCAGCTGAACTGATTCTCCAACGTGAACAGCATCTGTCGGCGCTCGATGGTCTGG
CCGCCGCCGCCGCGCATGAACTGGGCACGCCGCTTGCAACCATTGCGCTGGTGGTCAAGGAAATGCAGCGCGCCCATACG
AAGGATCCCGGCCTTGAGGAAGATATCGCGCTTCTTCATTCGCAAACGCAGCGCTGCCGCGAAATTCTGCAACGGCTGAC
CAGCCTTTCCTCGGAAGGTGAGGAACATATGTCCCGCCTGCCGCTTTCCTCGTTGATCGAGGAAGTGATCGCACCACACC
GCAATTTCGGCATCATGATCGAGGTTCAAAAGGAAGAGGGCCCCAAGCCCGAGCCTGTGACCCGCCGCAATCCGGGCCTG
CTTTACGGCCTTGGCAATCTGGTGGAAAACGCCGTCGATTTCGCGCGCGGCGAGGTTACTGTCACATGGGGCTGGACGGA
CGGCCATGTCAGCGTCACCATTCAGGACGATGGCGAGGGCTTCCGGCCGGAAATCCTCGACCGCATCGGTGAGCCCTATA
TGACGAGCCGCGACAACACCCGCAATGGTGGCGGGCTCGGCCTTGGGCTGTTCATCGCCAAGACCCTTTTGGAGCGTTCC
GGCGCGCAGATCAGCTTCCGCAATCGCAGCAATCCCGGTCAGGGGGCGGAGGTGAAAGTCACCTGGCCGCGTTCGGCCTT
CAGCGCGAGCTAG

Upstream 100 bases:

>100_bases
ACCTGAGATATTCGGTTCTGACGGCCCTGCGACCGGATAACGCAGTTTTGCTTGCATTCCTGTCCGGCCTTGCCTCATAA
GAGGCCTGACGAGGGACCCC

Downstream 100 bases:

>100_bases
GGCTTGTCTGCATTCAAGGATTCCCTTTTGCATGAAATTCTGATTCAAGGTTGTTGAAGGAGAACAGCCTTGAGCAGACG
AAGCCTTACAGATGAGCAAT

Product: sensor histidine kinase regB

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MHAEFENRASNLSRRPRLTTLVRVRWLAIAGQTAAVMFVALYLQFPFSVGICFALIACSAWLNLYLAFRFPANHRLNPTA
ASLVLAFDVLQLAGLLYLTGGLQNPFIVLMIVPVIISATSLSARDTIVLALLVVACTSFLTIHYDPLPWYPGETLNLPLL
FVIGIWCAIISALGFTGVYAYRIAEEARQLGDALSAAELILQREQHLSALDGLAAAAAHELGTPLATIALVVKEMQRAHT
KDPGLEEDIALLHSQTQRCREILQRLTSLSSEGEEHMSRLPLSSLIEEVIAPHRNFGIMIEVQKEEGPKPEPVTRRNPGL
LYGLGNLVENAVDFARGEVTVTWGWTDGHVSVTIQDDGEGFRPEILDRIGEPYMTSRDNTRNGGGLGLGLFIAKTLLERS
GAQISFRNRSNPGQGAEVKVTWPRSAFSAS

Sequences:

>Translated_430_residues
MHAEFENRASNLSRRPRLTTLVRVRWLAIAGQTAAVMFVALYLQFPFSVGICFALIACSAWLNLYLAFRFPANHRLNPTA
ASLVLAFDVLQLAGLLYLTGGLQNPFIVLMIVPVIISATSLSARDTIVLALLVVACTSFLTIHYDPLPWYPGETLNLPLL
FVIGIWCAIISALGFTGVYAYRIAEEARQLGDALSAAELILQREQHLSALDGLAAAAAHELGTPLATIALVVKEMQRAHT
KDPGLEEDIALLHSQTQRCREILQRLTSLSSEGEEHMSRLPLSSLIEEVIAPHRNFGIMIEVQKEEGPKPEPVTRRNPGL
LYGLGNLVENAVDFARGEVTVTWGWTDGHVSVTIQDDGEGFRPEILDRIGEPYMTSRDNTRNGGGLGLGLFIAKTLLERS
GAQISFRNRSNPGQGAEVKVTWPRSAFSAS
>Mature_430_residues
MHAEFENRASNLSRRPRLTTLVRVRWLAIAGQTAAVMFVALYLQFPFSVGICFALIACSAWLNLYLAFRFPANHRLNPTA
ASLVLAFDVLQLAGLLYLTGGLQNPFIVLMIVPVIISATSLSARDTIVLALLVVACTSFLTIHYDPLPWYPGETLNLPLL
FVIGIWCAIISALGFTGVYAYRIAEEARQLGDALSAAELILQREQHLSALDGLAAAAAHELGTPLATIALVVKEMQRAHT
KDPGLEEDIALLHSQTQRCREILQRLTSLSSEGEEHMSRLPLSSLIEEVIAPHRNFGIMIEVQKEEGPKPEPVTRRNPGL
LYGLGNLVENAVDFARGEVTVTWGWTDGHVSVTIQDDGEGFRPEILDRIGEPYMTSRDNTRNGGGLGLGLFIAKTLLERS
GAQISFRNRSNPGQGAEVKVTWPRSAFSAS

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=26.3392857142857, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47077; Mature: 47077

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAEFENRASNLSRRPRLTTLVRVRWLAIAGQTAAVMFVALYLQFPFSVGICFALIACSA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLNLYLAFRFPANHRLNPTAASLVLAFDVLQLAGLLYLTGGLQNPFIVLMIVPVIISATS
HHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
LSARDTIVLALLVVACTSFLTIHYDPLPWYPGETLNLPLLFVIGIWCAIISALGFTGVYA
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YRIAEEARQLGDALSAAELILQREQHLSALDGLAAAAAHELGTPLATIALVVKEMQRAHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
KDPGLEEDIALLHSQTQRCREILQRLTSLSSEGEEHMSRLPLSSLIEEVIAPHRNFGIMI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEE
EVQKEEGPKPEPVTRRNPGLLYGLGNLVENAVDFARGEVTVTWGWTDGHVSVTIQDDGEG
EEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCC
FRPEILDRIGEPYMTSRDNTRNGGGLGLGLFIAKTLLERSGAQISFRNRSNPGQGAEVKV
CCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEE
TWPRSAFSAS
ECCCCCCCCC
>Mature Secondary Structure
MHAEFENRASNLSRRPRLTTLVRVRWLAIAGQTAAVMFVALYLQFPFSVGICFALIACSA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLNLYLAFRFPANHRLNPTAASLVLAFDVLQLAGLLYLTGGLQNPFIVLMIVPVIISATS
HHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
LSARDTIVLALLVVACTSFLTIHYDPLPWYPGETLNLPLLFVIGIWCAIISALGFTGVYA
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YRIAEEARQLGDALSAAELILQREQHLSALDGLAAAAAHELGTPLATIALVVKEMQRAHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
KDPGLEEDIALLHSQTQRCREILQRLTSLSSEGEEHMSRLPLSSLIEEVIAPHRNFGIMI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEE
EVQKEEGPKPEPVTRRNPGLLYGLGNLVENAVDFARGEVTVTWGWTDGHVSVTIQDDGEG
EEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCC
FRPEILDRIGEPYMTSRDNTRNGGGLGLGLFIAKTLLERSGAQISFRNRSNPGQGAEVKV
CCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEE
TWPRSAFSAS
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]